Klebsiella

Common Name(s)

Klebsiella

Klebsiella infections refer to several different types of healthcare-associated infections that are all caused by the Klebsiella bacteria, including pneumonia; bloodstream infections; wound or surgical site infections; and meningitis. Healthy people usually do not get Klebsiella infections. However, people who are hospitalized and receiving treatment for other conditions may be susceptible to these infections. In healthcare settings, people who require long courses of antibiotics and/or devices such as ventilators (breathing machines) or intravenous (vein) catheters are at the most risk for Klebsiella infections. These infections are often treated with antibiotics, although some Klebsiella bacteria may be resistant to certain types of antibiotics.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Klebsiella" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Klebsiella" returned 1673 free, full-text research articles on human participants. First 3 results:

High-dose tigecycline for the treatment of nosocomial carbapenem-resistant Klebsiella pneumoniae bloodstream infections: A retrospective cohort study.
 

Author(s): Ting-Ting Geng, Xin Xu, Man Huang

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9961.

 

Carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection (BSI) has become increasingly frequent threat recently, especially in the intensive care unit (ICU). High-dose tigecycline (TGC) regimen is proposed due to the limitation of treatment options. We investigated ...

Last Updated: 31 Dec 1969

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Update of incidence and antimicrobial susceptibility trends of Escherichia coli and Klebsiella pneumoniae isolates from Chinese intra-abdominal infection patients.
 

Author(s): Hui Zhang, Qiwen Yang, Kang Liao, Yuxing Ni, Yunsong Yu, Bijie Hu, Ziyong Sun, Wenxiang Huang, Yong Wang, Anhua Wu, Xianju Feng, Yanping Luo, Yunzhuo Chu, Shulan Chen, Bin Cao, Jianrong Su, Qiong Duan, Shufang Zhang, Haifeng Shao, Haishen Kong, Bingdong Gui, Zhidong Hu, Robert Badal, Yingchun Xu

Journal:

 

To evaluate in vitro susceptibilities of aerobic and facultative Gram-negative bacterial (GNB) isolates from intra-abdominal infections (IAIs) to 12 selected antimicrobials in Chinese hospitals from 2012 to 2014.

Last Updated: 31 Dec 1969

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First case of New Delhi metallo-β-lactamase in Klebsiella pneumoniae from Ecuador: An update for South America.
 

Author(s): Daniel Romero-Alvarez, Jorge Reyes, Viviana Quezada, Carolina Satán, Nelson Cevallos, Sofía Barrera, Gabriel Trueba, Luis E Escobar, José E Villacís

Journal: Int. J. Infect. Dis.. 2017 Dec;65():119-121.

 

To describe a clinical case of Klebsiella pneumoniae harboring a New Delhi metallo-β-lactamase (NDM) plasmid in Ecuador and to present a map of reports of NDM isolates in South America.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Klebsiella" returned 32 free, full-text review articles on human participants. First 3 results:

A Klebsiella pneumoniae liver abscess presenting with myasthenia and tea-colored urine: A case report and review of 77 cases of bacterial rhabdomyolysis.
 

Author(s): Lihua Deng, Rong Jia, Wei Li, Qian Xue, Jie Liu, Yide Miao, Jingtong Wang

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9458.

 

Rhabdomyolysis is a well-known syndrome in clinical practice, although rhabdomyolysis caused by a liver abscess is rarely reported and the patient may lack symptoms that are associated with a primary site of infection. Early recognition of this possibility is needed to avoid diagnostic ...

Last Updated: 31 Dec 1969

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Triple combination antibiotic therapy for carbapenemase-producing Klebsiella pneumoniae: a systematic review.
 

Author(s): David M Jacobs, M Courtney Safir, Dennis Huang, Faisal Minhaj, Adam Parker, Gauri G Rao

Journal:

 

The spread of carbapenemase-producing K. pneumoniae (CPKP) has become a significant problem worldwide. Combination therapy for CPKP is encouraging, but polymyxin resistance to many antibiotics is hampering effective treatment. Combination therapy with three or more antibiotics is ...

Last Updated: 31 Dec 1969

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Hypervirulence and hypermucoviscosity: Two different but complementary Klebsiella spp. phenotypes?
 

Author(s): Juan Carlos Catalán-Nájera, Ulises Garza-Ramos, Humberto Barrios-Camacho

Journal: Virulence. 2017 10;8(7):1111-1123.

 

Since the hypermucoviscous variants of Klebsiella pneumoniae were first reported, many cases of primary liver abscesses and other invasive infections caused by this pathogen have been described worldwide. Hypermucoviscosity is a phenotypic feature characterized by the formation of ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Epidemiological Characteristics and Treatment Protocol for Carbapenem-Resistant Klebsiella Pneumoniae in China
 

Status: Not yet recruiting

Condition Summary: Klebsiella Pneumoniae Infection

 

Last Updated: 9 Aug 2017

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Antibiotics for Klebsiella Liver Abscess Study
 

Status: Recruiting

Condition Summary: Liver Abscess, Pyogenic

 

Last Updated: 13 Apr 2017

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Polymyxin B Monotherapy vs Combination Therapy in Critically Ill Patients With Multi-drug Resistant Pathogens
 

Status: Recruiting

Condition Summary: Trauma; Resistant Infection; Critical Illness

 

Last Updated: 14 May 2018

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