Kleeblattschaedel

Common Name(s)

Kleeblattschaedel, Cloverleaf skull

Kleeblattschaedel or "cloverleaf skull" is a term used to describe the shape of a malformed skull which consists of three lobes. This malformation occurs when the bones of the skull fuse (close) prematurely, or too early in development. This causes other facial and head abnormalities such as downward displacement of the ears so that they face the shoulders, flattened nose, widely spaced eyes, bulging of the eyes, and difficulties closing the eyelids completely. Hydrocephalus (also known as "water on the brain"), an abnormal build up fluid from the spinal cord and brain occurs in the spaces around the brain, is often associated with Kleeblattschaedel as well. Kleeblattschaedel may occur alone (isolated finding) or along with other abnormalities that make up various genetic syndromes. When isolated, this condition is more common in females than males and occurs sporadically (randomly, not inherited). It may be diagnosed during pregnancy by ultrasound or will be evident at birth. Early death has occured in most documented cases.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kleeblattschaedel" for support, advocacy or research.

Children's Craniofacial Association

Empowering and giving hope to individuals and families affected by facial differences.

Last Updated: 13 Jul 2015

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Craniofacial Foundation of America

The Craniofacial Foundation of America (CFA) is a nonprofit organization that supports the work of the Tennessee Craniofacial Center at Children's Hospital and Erlanger Health System in Chattanooga, Tennessee. The CFA is dedicated to providing support for individuals with facial disfigurement from birth defects, tumors and trauma.

Last Updated: 13 Jul 2015

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FACES, The National Craniofacial Association

The National Craniofacial Association is a nonprofit organization serving children and adults throughout the United States with severe craniofacial deformities resulting from birth defects, injuries or disease.

Last Updated: 13 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kleeblattschaedel" for support, advocacy or research.

Children's Craniofacial Association

Empowering and giving hope to individuals and families affected by facial differences.

http://www.ccakids.org

Last Updated: 13 Jul 2015

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Craniofacial Foundation of America

The Craniofacial Foundation of America (CFA) is a nonprofit organization that supports the work of the Tennessee Craniofacial Center at Children's Hospital and Erlanger Health System in Chattanooga, Tennessee. The CFA is dedicated to providing support for individuals with facial disfigurement from birth defects, tumors and trauma.

http://www.craniofacialfoundation.org

Last Updated: 13 Jul 2015

View Details
FACES, The National Craniofacial Association

The National Craniofacial Association is a nonprofit organization serving children and adults throughout the United States with severe craniofacial deformities resulting from birth defects, injuries or disease.

http://www.faces-cranio.org

Last Updated: 13 Jul 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kleeblattschaedel" returned 0 free, full-text research articles on human participants.

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kleeblattschaedel" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.