Lactic Acidosis

Common Name(s)

Lactic Acidosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

Last Updated: 28 Jul 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

http://www.umdf.org

Last Updated: 28 Jul 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lactic Acidosis" returned 301 free, full-text research articles on human participants. First 3 results:

[Metformin-associated lactic acidosis. Report of one case].
 

Author(s): Felipe Quintana, María José Pezzani, Rodrigo Orozco, Jorge Dreyse, Leonardo Soto, Tomás Regueira

Journal: Rev Med Chil. 2017 Aug;145(8):1072-1075.

 

Metformin-associated lactic acidosis is a severe and infrequent adverse event. Early diagnosis is essential to start an early treatment, which often has favorable results. We report a 56 years old non-insulin-requiring type 2 diabetic female who developed a severe metabolic acidosis ...

Last Updated: 31 Dec 1969

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Last Updated: 31 Dec 1969

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Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS) due to a m.10158T>C ND3 Mutation with a Normal Muscle Biopsy.
 

Author(s): Josef Finsterer, Sinda Zarrouk-Mahjoub

Journal: Intern. Med.. 2017 10;56(19):2693.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lactic Acidosis" returned 33 free, full-text review articles on human participants. First 3 results:

Lactic acidosis: an update.
 

Author(s): Jansen Seheult, Gerard Fitzpatrick, Gerard Boran

Journal: Clin. Chem. Lab. Med.. 2017 Mar;55(3):322-333.

 

Lactate is one of the most crucial intermediates in carbohydrate and nonessential amino acid metabolism. The complexity of cellular interactions and metabolism means that lactate can be considered a waste product for one cell but a useful substrate for another. The presence of elevated ...

Last Updated: 31 Dec 1969

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Trimethoprim/Sulfamethoxazole-Induced Severe Lactic Acidosis: A Case Report and Review of the Literature.
 

Author(s): Marie Bulathsinghala, Kimberly Keefer, Andry Van de Louw

Journal: Medicine (Baltimore). 2016 Apr;95(17):e3478.

 

Propylene glycol (PG) is used as a solvent in numerous medications, including trimethoprim/sulfamethoxazole (TMP/SMX) and lorazepam, and is metabolized in the liver to lactic acid. Cases of lactic acidosis related to PG toxicity have been described and always involved large doses ...

Last Updated: 31 Dec 1969

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Metformin-associated lactic acidosis: Current perspectives on causes and risk.
 

Author(s): Ralph DeFronzo, G Alexander Fleming, Kim Chen, Thomas A Bicsak

Journal: Metab. Clin. Exp.. 2016 Feb;65(2):20-9.

 

Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the risk of lactic acidosis. Metformin, along with other drugs in the biguanide class, increases plasma lactate levels in a plasma concentration-dependent ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Investigation of the Correlation Between Plasma Concentration of Linezolid Antibiotic and Treatment Response and Adverse Reactions
 

Status: Recruiting

Condition Summary: Myelosuppression; Lactic Acidosis; Peripheral Neuropathy

 

Last Updated: 26 Apr 2017

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Lactate Acidosis in Postoperative Hearts
 

Status: Recruiting

Condition Summary: Post-cardiac Surgery; Hyperlactatemia

 

Last Updated: 19 Jan 2018

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Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest
 

Status: Recruiting

Condition Summary: Cardiac Arrest; Shock; Lactic Acidosis; Thiamin Deficiency

 

Last Updated: 7 Sep 2017

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