Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1401 free, full-text research articles on human participants. First 3 results:

Adrenal relapse of primary central nervous system diffuse large B-cell lymphoma: A case report.
 

Author(s): Shuang Ma, Siddhartha Sen Sen, Rachel Jug, Xuefeng Zhang, Wan-Lin Zhang, Shuai Shen, Cheng-Qian Yu, Hong-Tao Xu, Lian-He Yang, Endi Wang

Journal: Medicine (Baltimore). 2018 Sep;97(38):e12482.

 

Primary central nervous system lymphoma (PCNSL) is a rare form of non-Hodgkin lymphoma with a dismal outcome. Most patients relapse in intracranial sites and <5% of patients relapse in extracranial sites. Here, we present the first case of PCNSL with an adrenal relapse.

Last Updated: 31 Dec 1969

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Genetics of Diffuse Large B-Cell Lymphoma.
 

Author(s): George W Wright, Wyndham H Wilson, Louis M Staudt

Journal: N. Engl. J. Med.. 2018 08;379(5):493-494.

 

Last Updated: 31 Dec 1969

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Monoclonal gammopathies regardless of subtypes are associated with poor prognosis of diffuse large B-cell lymphoma: A STROBE-compliant article.
 

Author(s): Yian Zhang, Zheng Wei, Jing Li, Rupan Gao, Peng Liu

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11719.

 

Monoclonal gammopathy (MG), a positive result of serum immunofixation electrophoresis (SIFE), has been reported in cases of diffuse large B-cell lymphoma (DLBCL). We performed this study to further investigate the prognostic value of MG in DLBCL.We retrospectively reviewed patients ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 112 free, full-text review articles on human participants. First 3 results:

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
 

Author(s): Khadega A Abuelgasim, Hinna Rehan, Maha Alsubaie, Nasser Al Atwi, Mohammed Al Balwi, Saeed Alshieban, Areej Almughairi

Journal:

 

Chronic lymphocytic leukemia and chronic myeloid leukemia are the most common types of adult leukemia. However, it is rare for the same patient to suffer from both. Richter's transformation to diffuse large B-cell lymphoma is frequently observed in chronic lymphocytic leukemia. Purine ...

Last Updated: 31 Dec 1969

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Isolated skeletal muscle recurrence of an originally nodal diffuse large B cell lymphoma: A case report and review of the literature.
 

Author(s): Nikolaos Spetsieris, Nefeli Giannakopoulou, Eleni Variami, Konstantinos Zervakis, Niki Rougala, Georgios Garefalakis, Vasiliki Skarlatou, Nora-Athina Viniou, Panagiotis Diamantopoulos

Journal: Medicine (Baltimore). 2018 Jan;97(3):e9608.

 

Diffuse large B cell lymphoma (DLBCL) is a malignancy of the B cells with extranodal primary involvement being estimated at 30% to 40% of cases. Primary skeletal muscle presentation of DLBCL is extremely rare, with an estimated incidence of about 0.5% of extranodal lymphomas, presenting ...

Last Updated: 31 Dec 1969

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CT and PET/CT findings of primary pulmonary diffuse large B-cell lymphoma: One case report and literature review.
 

Author(s): Yanjun Bai, Wenjie Liang

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8876.

 

Primary pulmonary diffuse large B-cell lymphoma (PPL-DLBCL) is rare and its clinical manifestations lack specificity. In this report, we present one case of PPL-DLBCL with complete clinical and imaging data, including uncontrast-enhanced CT, contrast-enhanced CT, and positron emission ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma
 

Status: Not yet recruiting

Condition Summary: Large B-Cell Diffuse Lymphoma

 

Last Updated: 13 Jul 2018

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Idelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies
 

Status: Recruiting

Condition Summary: B Cells-Tumors; B Cell Chronic Lymphocytic Leukemia; Follicular Lymphoma; Mantle Cell Lymphoma; Large B-Cell Diffuse Lymphoma of Bone (Diagnosis)

 

Last Updated: 5 Sep 2018

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