Lateral meningocele syndrome

Common Name(s)

Lateral meningocele syndrome

Lateral meningocele syndrome (LMS) is a rare hereditary connective tissue disorder. This condition results from a mutation or error in a person's DNA or genes. A meningocele occurs when the outer part of the spine has not completely closed, leaving an opening. The spinal cord itself may not be affected, but its coverings (the meninges) are damaged and pushed through the opening. With a meningocele, the spinal cord stays inside the back where it belongs. This means that most children with a meningocele will have normal movement and normal feeling in their legs and feet. Other symptoms may include craniofacial anomalies. Although there is currently no cure for lateral meningocele syndrome, there are various resources to help manage the condition and treat birth defects. Doctors seek help from various therapists and community services to provide support and care for families affected by this disorder. Lateral meningocele syndrome has been described in eleven patients.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lateral meningocele syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lateral meningocele syndrome" returned 1 free, full-text research articles on human participants. First 3 results:

Truncating mutations in the last exon of NOTCH3 cause lateral meningocele syndrome.
 

Author(s): Karen W Gripp, Katherine M Robbins, Nara L Sobreira, P Dane Witmer, Lynne M Bird, Kristiina Avela, Outi Makitie, Daniela Alves, Jacob S Hogue, Elaine H Zackai, Kimberly F Doheny, Deborah L Stabley, Katia Sol-Church

Journal: Am. J. Med. Genet. A. 2015 Feb;167A(2):271-81.

 

Lateral meningocele syndrome (LMS, OMIM%130720), also known as Lehman syndrome, is a very rare skeletal disorder with facial anomalies, hypotonia and meningocele-related neurologic dysfunction. The characteristic lateral meningoceles represent the severe end of the dural ectasia spectrum ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

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The terms "Lateral meningocele syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.