Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 536 free, full-text research articles on human participants. First 3 results:

[Bladder leiomyosarcoma: about 3 cases].
 

Author(s): Kadouri Youssef, Ousmane Nago Dembele, Ziani Idriss, Hachem Elsayegh, Ali Iken, Lounis Benslimane, Yassine Nouini

Journal:

 

Bladder leiomyosarcoma is a rare highly malignant tumor. It can occur in children and adults with a maximum incidence in patients over 60 years of age. It mainly affects men, with a sex ratio of 3/1. Its clinical features are non-specific and dominated by the haematuria. Endoscopic ...

Last Updated: 31 Dec 1969

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Anterior mediastinal leiomyosarcoma mimicking thymoma: A case report.
 

Author(s): Xing Xue, Wenjie Liang, Wenjuan Zhang

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11132.

 

Mediastinal leiomyosarcoma is very rare. In this paper, we report one case of anterior mediastinal leiomyosarcoma and retrospectively review the imaging findings of previously reported cases.

Last Updated: 31 Dec 1969

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Cutaneous leiomyosarcoma on the face.
 

Author(s): Nathalia Dias Negrão Murback, Luiz C Takita, Bruna Corrêa de Castro, Gunter Hans Filho

Journal: An Bras Dermatol. 2018 Mar;93(2):262-264.

 

Leiomyosarcoma is a rare skin tumor, most common in white men in the fifth to eighth decades of life. Primary tumors are classified in dermal or subcutaneous, that differ by clinical and prognostic features. They may appear on any site of the body, but are rare on the face. A 54-year-old ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 88 free, full-text review articles on human participants. First 3 results:

Primary leiomyosarcoma of the fallopian tube: A case report and literature review.
 

Author(s): Di You, Qilin Wang, Wei Jiang, Lin Lin, Tianjin Yi, Lingjun Zhao, Maomao Li, Ping Wang

Journal: Medicine (Baltimore). 2018 Apr;97(17):e0536.

 

Primary leiomyosarcoma (LMS) of the fallopian tube is extremely uncommon. To the best of our knowledge, so far only 21 cases of primary fallopian tube LMS have been reported in English-language literature. No new case has been reported in the past 7 years.

Last Updated: 31 Dec 1969

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Molecular biomarkers for uterine leiomyosarcoma and endometrial stromal sarcoma.
 

Author(s): Hideaki Tsuyoshi, Yoshio Yoshida

Journal: Cancer Sci.. 2018 Jun;109(6):1743-1752.

 

Uterine leiomyosarcoma (u-LMS) and endometrial stromal sarcoma (ESS) are among the most frequent soft tissue sarcomas, which, in adults, lead to fatal lung metastases and patients have an extremely poor prognosis. Due to their rarity and heterogeneity, there are no suitable biomarkers ...

Last Updated: 31 Dec 1969

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Gingival Leiomyosarcoma in a Young Woman: Case report and literature review.
 

Author(s): Massimo Viviano, Clelia Miracco, Guido Lorenzini, Gennaro Baldino, Serena Cocca

Journal: Sultan Qaboos Univ Med J. 2017 Nov;17(4):e472-e476.

 

Leiomyosarcoma (LMS) is a rare mesenchymal malignancy, of which 3-10% of cases occur in the head and neck region. We report a 22-year-old woman who was referred to the University Hospital of Siena, Italy, in 2016 with an ostensibly benign asymptomatic lump on the mandibular . The ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trabectedin, Doxorubicin and Olaratumab in Patients With Metastatic or Recurrent Leiomyosarcoma
 

Status: Not yet recruiting

Condition Summary: Leiomyosarcoma

 

Last Updated: 11 Aug 2018

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Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment
 

Status: Not yet recruiting

Condition Summary: Leiomyosarcoma Metastatic

 

Last Updated: 23 May 2018

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Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma
 

Status: Not yet recruiting

Condition Summary: Uterine or Soft Tissue Leiomyosarcoma

 

Last Updated: 6 Jan 2017

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