Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 2419 free, full-text research articles on human participants. First 3 results:

Combination therapy with liposomal amphotericin b (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate in a refractory visceral leishmaniasis case.
 

Author(s): Maria Antonia Ferreira Gomes, Lana Lira Cantidio de Medeiros, Fernanda Paula Dantas Lobo, Nathália Rayane Silva Wanderley, Ana Paula Rodrigues Matos, Tácito do Nascimento Jácome, Maria Goretti Lins Monteiro, Kleber Giovanni Luz

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):393-396.

 

Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral ...

Last Updated: 31 Dec 1969

Go To URL
Molecular diagnosis of cutaneous leishmaniasis in an endemic area of Acre State in the Amazonian Region of Brazil.
 

Author(s): Thais de Araujo-Pereira, Daniela de Pita-Pereira, Regina Barbosa Moreira, Tainah Silva-Galdino, Márcia P de Oliveira Duarte, Reginaldo Peçanha Brazil, Constança Britto

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):376-381.

 

This study proposes to identify the Leishmania species found in the skin lesions of cutaneous leishmaniasis (CL) patients from Brasiléia municipality (Acre).

Last Updated: 31 Dec 1969

Go To URL
Mucosal leishmaniasis: the experience of a Brazilian referral center.
 

Author(s): Mariana Junqueira Pedras, Janaína de Pina Carvalho, Rosiana Estéfane da Silva, Dario Brock Ramalho, Maria Camilo Ribeiro de Senna, Hugo Silva Assis Moreira, Lorena Zaine Matos Martinho, Ana Rabello, Gláucia Cota

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):318-323.

 

Pentavalent antimonials (Sbv) are the most commonly used drugs for the treatment of mucosal leishmaniasis (ML), despite their high toxicity and only moderate efficacy. The aim of this study was to report therapeutic responses with different available options for ML.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 259 free, full-text review articles on human participants. First 3 results:

New insights into leishmaniasis in the immunosuppressed.
 

Author(s): Hannah Akuffo, Carlos Costa, Johan van Griensven, Sakib Burza, Javier Moreno, Mercè Herrero

Journal:

 

Immunosuppression contributes significantly to the caseload of visceral leishmaniasis (VL). HIV coinfection, solid organ transplantation, malnutrition, and helminth infections are the most important immunosuppression-related factors. This review briefly describes the challenges of ...

Last Updated: 31 Dec 1969

Go To URL
Human leishmaniasis in Brazil: A general review.
 

Author(s): Laís Anversa, Monique Gomes Salles Tiburcio, Virgínia Bodelão Richini-Pereira, Luis Eduardo Ramirez

Journal: Rev Assoc Med Bras (1992). 2018 Mar;64(3):281-289.

 

Leishmaniasis is a disease with ample clinical spectrum and epidemiological diversity and is considered a major public health problem. This article presents an overview of the transmission cycles, host-parasite interactions, clinical, histological and immunological aspects, diagnosis ...

Last Updated: 31 Dec 1969

Go To URL
Tegumentary leishmaniasis and coinfections other than HIV.
 

Author(s): Dalila Y Martínez, Kristien Verdonck, Paul M Kaye, Vanessa Adaui, Katja Polman, Alejandro Llanos-Cuentas, Jean-Claude Dujardin, Marleen Boelaert

Journal:

 

Tegumentary leishmaniasis (TL) is a disease of skin and/or mucosal tissues caused by Leishmania parasites. TL patients may concurrently carry other pathogens, which may influence the clinical outcome of TL.

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Predicting Visceral Leishmaniasis in HIV Infected Patients
 

Status: Recruiting

Condition Summary: Leishmaniasis, Visceral

 

Last Updated: 25 Apr 2018

Go to URL

Last Updated: 11 Nov 2017

Go to URL
Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucocutaneous Leishmaniasis

 

Last Updated: 6 Mar 2018

Go to URL