Leprosy

Common Name(s)

Leprosy

Leprosy is a disease caused by the bacterium Mycobacterium leprae. Due to its long incubation period, it is difficult to know where or when someone has caught the disease, though children are more likely than adults to contract it. Leprosy is common in many countries, especially in temperate, tropical, and subtropical climates. Symptoms of leprosy include skin lesions, muscle weakness, and numbness. It is not highly infectious, but is transmitted through droplets from close contact with infected persons. Although leprosy is curable and treatment is available, if left untreated, leprosy can cause progressive and permanent damage to the skin, nerves, limbs, and eyes.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leprosy" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leprosy" returned 1566 free, full-text research articles on human participants. First 3 results:

Genotyping of Mycobacterium leprae for better understanding of leprosy transmission in Fortaleza, Northeastern Brazil.
 

Author(s): Amanda N B Fontes, Luana N G C Lima, Rosa M S Mota, Rosa L F Almeida, Maria A Pontes, Heitor de S Gonçalves, Cristiane C Frota, Varalakshmi D Vissa, Patrick J Brennan, Ricardo J P S Guimaraes, Carl Kendall, Ligia R F S Kerr, Philip N Suffys

Journal:

 

Leprosy is endemic in large part of Brazil with 28,761 new patients in 2015, the second largest number worldwide and reaches 9/10.000 in highly endemic regions and 2.7/10.000 in the city of Fortaleza, Ceará, Northeast Brazil. For better understanding of risk factors for leprosy transmission, ...

Last Updated: 31 Dec 1969

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Longitudinal assessment of anti-PGL-I serology in contacts of leprosy patients in Bangladesh.
 

Author(s): Renate A Richardus, Konrad van der Zwet, Anouk van Hooij, Louis Wilson, Linda Oskam, Roel Faber, Susan J F van den Eeden, David Pahan, Khorshed Alam, Jan Hendrik Richardus, Annemieke Geluk

Journal:

 

Despite elimination efforts, the number of Mycobacterium leprae (M. leprae) infected individuals who develop leprosy, is still substantial. Solid evidence exists that individuals living in close proximity to patients are at increased risk to develop leprosy. Early diagnosis of leprosy ...

Last Updated: 31 Dec 1969

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ELISA-based assay of immunoglobulin G antibodies against mammalian cell entry 1A (Mce1A) protein: a novel diagnostic approach for leprosy.
 

Author(s): Filipe R Lima, Iukary Takenami, Maurílio Al Cavalcanti, Lee W Riley, Sérgio Arruda

Journal: Mem. Inst. Oswaldo Cruz. 2017 Dec;112(12):844-849.

 

Leprosy is a chronic infectious disease caused by the obligate intracellular bacillus Mycobacterium leprae. Because leprosy diagnosis is complex and requires professional expertise, new tools and methodologies are needed to detect cases in early stages and prevent transmission. The ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leprosy" returned 110 free, full-text review articles on human participants. First 3 results:

Spatial distribution of leprosy in Brazil: a literature review.
 

Author(s): Cláuffer Luiz Machado Silva, Sandra Costa Fonseca, Helia Kawa, Dayanna de Oliveira Quintanilha Palmer

Journal: Rev. Soc. Bras. Med. Trop.. ;50(4):439-449.

 

Leprosy remains a public health problem in developing countries. Among communicable diseases, it is one of the leading causes of permanent disability. Brazil had not reached the goal of reducing cases to less than 1 per 10,000 population. This study aimed to analyze the spatial distribution ...

Last Updated: 31 Dec 1969

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Leprosy - one of the many forgotten tropical diseases.
 

Author(s): Zofia Zwolska, Ewa Augustynowicz-Kopeć

Journal:

 

Leprosy or Hansen disease is caused by an infection of Mycobacterium leprae. The large number of undetected cases (2000-2012 years 4 mln people) remains a threat to the elimination of leprosy. Leprosy is an unheard in Poland and generally is considered a condition so "exotic" that ...

Last Updated: 31 Dec 1969

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Historical Overview of Leprosy Control in Cuba.
 

Author(s): Enrique Beldarraín-Chaple

Journal: MEDICC Rev. 2017 Jan;19(1):23-30.

 

INTRODUCTION Leprosy, an infectious disease caused by Mycobacterium leprae, affects the nervous system, skin, internal organs, extremities and mucous membranes. Biological, social and environmental factors influence its occurrence and transmission. The first effective treatments appeared ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.
 

Status: Recruiting

Condition Summary: Leprosy Neuropathy

 

Last Updated: 1 Mar 2017

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A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary Leprosy
 

Status: Not yet recruiting

Condition Summary: Leprosy, Multibacillary

 

Last Updated: 2 Jan 2018

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Treatment of Neuropathic Pain in Leprosy
 

Status: Recruiting

Condition Summary: Pain, Neuropathic; Leprosy; Leprosy Neuropathy; Amitriptyline

 

Last Updated: 4 Nov 2017

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