Leprosy

Common Name(s)

Leprosy

Leprosy is a disease caused by the bacterium Mycobacterium leprae. Due to its long incubation period, it is difficult to know where or when someone has caught the disease, though children are more likely than adults to contract it. Leprosy is common in many countries, especially in temperate, tropical, and subtropical climates. Symptoms of leprosy include skin lesions, muscle weakness, and numbness. It is not highly infectious, but is transmitted through droplets from close contact with infected persons. Although leprosy is curable and treatment is available, if left untreated, leprosy can cause progressive and permanent damage to the skin, nerves, limbs, and eyes.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leprosy" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leprosy" returned 1571 free, full-text research articles on human participants. First 3 results:

Polyhexanide 0.2% in treatment of trophic foot ulcers in leprosy - preliminary study.
 

Author(s): Túlio Neutzling Zanchin, Cássio Battisti Serafini, Francine Silva Brandão, José Augusto da Costa Nery

Journal: An Bras Dermatol. ;93(1):145-147.

 

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which affects peripheral nerves, skin and mucous membranes. The impairment of neural function as well as sensory or sensory-motor disabilities in leprosy continue to be a problem that requires careful attention ...

Last Updated: 31 Dec 1969

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Leprosy and American cutaneous leishmaniasis coinfection.
 

Author(s): Larissa Mondadori Mercadante, Marcel Alex Soares Dos Santos, Elisangela Samartin Pegas, Bogdana Victória Kadunc

Journal: An Bras Dermatol. ;93(1):123-125.

 

Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same ...

Last Updated: 31 Dec 1969

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Anti-phospholipid syndrome in seven leprosy patients with thrombotic events on corticosteroid and/or thalidomide regimen: insights on genetic and laboratory profiles.
 

Author(s): Sebastian Vernal, Maria Jose Franco Brochado, Roberto Bueno-Filho, Paulo Louzada-Junior, Ana Maria Roselino

Journal: Rev. Soc. Bras. Med. Trop.. ;51(1):99-104.

 

Corticosteroids and/or thalidomides have been associated with thromboembolism events (TBE) in multibacillary (MB) leprosy. This report aimed to determine genetic and laboratory profiles associated with leprosy and TBE.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leprosy" returned 110 free, full-text review articles on human participants. First 3 results:

Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients.
 

Author(s): Rossilene Conceição da Silva Cruz, Samira Bührer-Sékula, Maria Lúcia F Penna, Gerson Oliveira Penna, Sinésio Talhari

Journal: An Bras Dermatol. ;92(6):761-773.

 

In this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adverse effects, evolution of the therapeutic ...

Last Updated: 31 Dec 1969

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Spatial distribution of leprosy in Brazil: a literature review.
 

Author(s): Cláuffer Luiz Machado Silva, Sandra Costa Fonseca, Helia Kawa, Dayanna de Oliveira Quintanilha Palmer

Journal: Rev. Soc. Bras. Med. Trop.. ;50(4):439-449.

 

Leprosy remains a public health problem in developing countries. Among communicable diseases, it is one of the leading causes of permanent disability. Brazil had not reached the goal of reducing cases to less than 1 per 10,000 population. This study aimed to analyze the spatial distribution ...

Last Updated: 31 Dec 1969

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Challenges beyond elimination in leprosy.
 

Author(s): Farah Naaz, Partha Sarathi Mohanty, Avi Kumar Bansal, Dilip Kumar, Umesh Datta Gupta

Journal: Int J Mycobacteriol. ;6(3):222-228.

 

Every year >200,000 new leprosy cases are registered globally. This number has been fairly stable over the past 8 years. The World Health Organization has set a target to interrupt the transmission of leprosy globally by 2020. It is important, in terms of global action and research ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.
 

Status: Recruiting

Condition Summary: Leprosy Neuropathy

 

Last Updated: 1 Mar 2017

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Last Updated: 15 May 2018

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A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary Leprosy
 

Status: Not yet recruiting

Condition Summary: Leprosy, Multibacillary

 

Last Updated: 22 May 2018

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