Leprosy

Common Name(s)

Leprosy

Leprosy is a disease caused by the bacterium Mycobacterium leprae. Due to its long incubation period, it is difficult to know where or when someone has caught the disease, though children are more likely than adults to contract it. Leprosy is common in many countries, especially in temperate, tropical, and subtropical climates. Symptoms of leprosy include skin lesions, muscle weakness, and numbness. It is not highly infectious, but is transmitted through droplets from close contact with infected persons. Although leprosy is curable and treatment is available, if left untreated, leprosy can cause progressive and permanent damage to the skin, nerves, limbs, and eyes.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leprosy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leprosy" returned 1608 free, full-text research articles on human participants. First 3 results:

Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy.
 

Author(s): Han-Siong Toh, Jeni Maharjan, Ruby Thapa, Kapil Dev Neupane, Mahesh Shah, Suwash Baral, Deanna A Hagge, Indra Bahadur Napit, Diana N J Lockwood

Journal:

 

Neuropathic pain (NP) can occur as a chronic complication of leprosy neuropathy. NP epidemiology and its impact on patients have not been well documented. This study investigates NP prevalence and impact in the years after patients are declared "released from treatment" (RFT) following ...

Last Updated: 31 Dec 1969

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Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.
 

Author(s): Moises B da Silva, Juliana M Portela, Wei Li, Mary Jackson, Mercedes Gonzalez-Juarrero, Andrea Sánchez Hidalgo, John T Belisle, Raquel C Bouth, Angélica R Gobbo, Josafá G Barreto, Antonio H H Minervino, Stewart T Cole, Charlotte Avanzi, Philippe Busso, Marco A C Frade, Annemieke Geluk, Claudio G Salgado, John S Spencer

Journal:

 

Mycobacterium leprae (M. leprae) is a human pathogen and the causative agent for leprosy, a chronic disease characterized by lesions of the skin and peripheral nerve damage. Zoonotic transmission of M. leprae to humans by nine-banded armadillos (Dasypus novemcinctus) has been shown ...

Last Updated: 31 Dec 1969

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Epidemiological profile of leprosy reactions in a referral center in Campinas (SP), Brazil, 2010-2015.
 

Author(s): Letícia Ambrosano, Marcel Alex Soares Dos Santos, Elaine Cristina Faria Abrahão Machado, Elisangela Samartin Pegas

Journal: An Bras Dermatol. 2018 Jun;93(3):460-461.

 

Leprosy patients can present reactions during the course of the disease. There are no official data on these reactions in Brazil. We aimed to describe the epidemiological characteristics of patients with such reactions, analyzing information from patient records at a referral center ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leprosy" returned 112 free, full-text review articles on human participants. First 3 results:

Socioeconomic risk markers of leprosy in high-burden countries: A systematic review and meta-analysis.
 

Author(s): Julia Moreira Pescarini, Agostino Strina, Joilda Silva Nery, Lacita Menezes Skalinski, Kaio Vinicius Freitas de Andrade, Maria Lucia F Penna, Elizabeth B Brickley, Laura C Rodrigues, Mauricio Lima Barreto, Gerson Oliveira Penna

Journal:

 

Over 200,000 new cases of leprosy are detected each year, of which approximately 7% are associated with grade-2 disabilities (G2Ds). For achieving leprosy elimination, one of the main challenges will be targeting higher risk groups within endemic communities. Nevertheless, the socioeconomic ...

Last Updated: 31 Dec 1969

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Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients.
 

Author(s): Rossilene Conceição da Silva Cruz, Samira Bührer-Sékula, Maria Lúcia F Penna, Gerson Oliveira Penna, Sinésio Talhari

Journal: An Bras Dermatol. ;92(6):761-773.

 

In this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adverse effects, evolution of the therapeutic ...

Last Updated: 31 Dec 1969

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Spatial distribution of leprosy in Brazil: a literature review.
 

Author(s): Cláuffer Luiz Machado Silva, Sandra Costa Fonseca, Helia Kawa, Dayanna de Oliveira Quintanilha Palmer

Journal: Rev. Soc. Bras. Med. Trop.. ;50(4):439-449.

 

Leprosy remains a public health problem in developing countries. Among communicable diseases, it is one of the leading causes of permanent disability. Brazil had not reached the goal of reducing cases to less than 1 per 10,000 population. This study aimed to analyze the spatial distribution ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.
 

Status: Recruiting

Condition Summary: Leprosy Neuropathy

 

Last Updated: 1 Mar 2017

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Last Updated: 15 May 2018

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A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary Leprosy
 

Status: Not yet recruiting

Condition Summary: Leprosy, Multibacillary

 

Last Updated: 17 Jul 2018

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