Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

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Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 656 free, full-text research articles on human participants. First 3 results:

Changes in leptospirosis etiology in animals and humans.
 

Author(s): Natalia Vasylieva, Mykhaylo Andreychyn, Yulia Kravchuk, –ělena Chervinska, Iaryna Iosyk

Journal: Ann Agric Environ Med. 2017 Dec;24(4):671-675.

 

Leptospirosis is endemic in Ternopil region. In Ukraine, the disease is registered in almost all regions, including the Ternopil region. The aim of the research is to study the regularities of epidemic and epizootic processes of leptospirosis, and the circulation of its pathogens ...

Last Updated: 31 Dec 1969

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Bovine leptospirosis in urban and peri-urban dairy farming in low-income countries: a "One Health" issue?
 

Author(s): Elisabeth Lindahl Rajala, Nosirjon Sattorov, Sofia Boqvist, Ulf Magnusson

Journal:

 

Global trends in urbanization are increasing the spread of neglected zoonotic infections such as leptospirosis, and reducing the number of human cases of leptospirosis is best accomplished by controlling the infection in the animal reservoir. The aim of this study was to determine ...

Last Updated: 31 Dec 1969

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Environmental risk of leptospirosis infections in the Netherlands: Spatial modelling of environmental risk factors of leptospirosis in the Netherlands.
 

Author(s): Ente J J Rood, Marga G A Goris, Roan Pijnacker, Mirjam I Bakker, Rudy A Hartskeerl

Journal:

 

Leptospirosis is a globally emerging zoonotic disease, associated with various climatic, biotic and abiotic factors. Mapping and quantifying geographical variations in the occurrence of leptospirosis and the surrounding environment offer innovative methods to study disease transmission ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 63 free, full-text review articles on human participants. First 3 results:

The Use of Chemoprophylaxis after Floods to Reduce the Occurrence and Impact of Leptospirosis Outbreaks.
 

Author(s): Maria Cristina Schneider, Jorge Velasco-Hernandez, Kyung-Duk Min, Deise Galan Leonel, David Baca-Carrasco, Matthew E Gompper, Rudy Hartskeerl, Claudia Munoz-Zanzi

Journal:

 

Record-breaking and devastating rainfall events have occurred in the past decade. Rain and floods are considered the main risk factors for leptospirosis and several outbreaks have been reported following extreme weather events. In such situations, one possible intervention to prevent ...

Last Updated: 31 Dec 1969

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Molecular diagnostics for human leptospirosis.
 

Author(s): Jesse J Waggoner, Benjamin A Pinsky

Journal: Curr. Opin. Infect. Dis.. 2016 Oct;29(5):440-5.

 

The definitive diagnosis of leptospirosis, which results from infection with spirochetes of the genus Leptospira, currently relies on the use of culture, serological testing (microscopic agglutination testing), and molecular detection. The purpose of this review is to describe new ...

Last Updated: 31 Dec 1969

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Micronutrients and Leptospirosis: A Review of the Current Evidence.
 

Author(s): Heather S Herman, Saurabh Mehta, Washington B C√°rdenas, Anna M Stewart-Ibarra, Julia L Finkelstein

Journal:

 

Leptospirosis is one of the most widespread zoonoses and represents a major threat to human health. Due to the high burden of disease, limitations in diagnostics, and limited coverage and availability of effective human and veterinary vaccines, leptospirosis remains an important neglected ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immune Response After Leptospirosis Infection
 

Status: Not yet recruiting

Condition Summary: Leptospirosis

 

Last Updated: 8 Sep 2016

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