Tetanus

Common Name(s)

Tetanus, Lockjaw

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 955 free, full-text research articles on human participants. First 3 results:

Paediatric otogenic tetanus: an evidence of poor immunization in Nigeria.
 

Author(s): Segun Ayodeji Ogunkeyede, Adekunle Daniel, Omowonuola Ogundoyin

Journal:

 

Suppurative otitis media is a common childhood infection that predisposes to otogenic tetanus. Tetanus is a vaccine preventable disease that is associated with high cost of care and mortality. This study highlights reasons for otogenic tetanus in Nigerian children and way of reducing ...

Last Updated: 4 Jul 2017

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[Tetanus after cat scratch and bites in a previously immunized patient].
 

Author(s): Alberto Fica, Daniela Gaínza, Pablo Ortigosa

Journal: Rev Chilena Infectol. 2017 Apr;34(2):181-185.

 

Tetanus is declining due to vaccination, professional labor management and appropriate wound care. Tetanus cases have been reported despite immunization. We report the case of a previously healthy 21 years old female patient that presented a mild generalized tetanus requiring admission ...

Last Updated: 20 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 36 free, full-text review articles on human participants. First 3 results:

Prevention of Tetanus Outbreak Following Natural Disaster in Indonesia: Lessons Learned from Previous Disasters.
 

Author(s): Dyshelly Nurkartika Pascapurnama, Aya Murakami, Haorile Chagan-Yasutan, Toshio Hattori, Hiroyuki Sasaki, Shinichi Egawa

Journal: Tohoku J. Exp. Med.. 2016 03;238(3):219-27.

 

In Indonesia, the Aceh earthquake and tsunami in 2004 killed 127,000 people and caused half a million injuries, while the Yogyakarta earthquake in 2006 caused 5,700 deaths and 37,000 injuries. Because disaster-affected areas are vulnerable to epidemic-prone diseases and tetanus is ...

Last Updated: 10 Mar 2016

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Meningococcal quadrivalent tetanus toxoid conjugate vaccine (MenACWY-TT, Nimenrix™): A review of its immunogenicity, safety, co-administration, and antibody persistence.
 

Author(s): Aia Assaf-Casals, Ghassan Dbaibo

Journal: Hum Vaccin Immunother. 2016 07;12(7):1825-37.

 

Meningococcal disease is a major cause of morbidity and mortality worldwide with reported epidemics and outbreaks in different parts of the world. Despite the availability of antimicrobial therapy, challenges remain in early recognition and prevention of disease. Several vaccines ...

Last Updated: 12 Jul 2016

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Eradication of tetanus.
 

Author(s): C L Thwaites, H T Loan

Journal: Br. Med. Bull.. 2015 ;116():69-77.

 

The causative agent of tetanus, Clostridium tetani is widespread in the environment throughout the world and cannot be eradicated. To reduce the number of cases of tetanus efforts are focussed on prevention using vaccination and post-exposure wound care.

Last Updated: 15 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vaccine -diphthEria -tetaNus -Acellular pertUssis-inactivated polioviruS
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 3 Feb 2017

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Evaluation of Immunogenicity, Safety and Reactogenicity of GSK Biologicals' Boostrix Vaccine Administered as a Booster Dose in Healthy Russian Subjects
 

Status: Not yet recruiting

Condition Summary: Diphtheria-Tetanus-acellular Pertussis Vaccines

 

Last Updated: 11 Oct 2017

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