Long QT syndrome 2

Common Name(s)

Long QT syndrome 2

Congenital long QT syndrome is electrocardiographically characterized by a prolonged QT interval and polymorphic ventricular arrhythmias (torsade de pointes). These cardiac arrhythmias may result in recurrent syncope, seizure, or sudden death ({7:Jongbloed et al., 1999}). For a discussion of genetic heterogeneity of long QT syndrome, see LQT1 ({192500}).
 

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Condition Specific Organizations

Following organizations serve the condition "Long QT syndrome 2" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Long QT syndrome 2" returned 40 free, full-text research articles on human participants. First 3 results:

Effect of Age and Sex on the QTc Interval in Children and Adolescents With Type 1 and 2 Long-QT Syndrome.
 

Author(s): Arja S Vink, Sally-Ann B Clur, Ronald B Geskus, Andreas C Blank, Charlotte C A De Kezel, Masao Yoshinaga, Nynke Hofman, Arthur A M Wilde, Nico A Blom

Journal: Circ Arrhythm Electrophysiol. 2017 Apr;10(4):.

 

In congenital long-QT syndrome, age, sex, and genotype have been associated with cardiac events, but their effect on the trend in QTc interval has never been established. We, therefore, aimed to assess the effect of age and sex on the QTc interval in children and adolescents with ...

Last Updated: 31 Dec 1969

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hERG long QT syndrome type 2 mutants need more than a chaperone to dance.
 

Author(s): David Fedida, Logan Macdonald

Journal: J. Physiol. (Lond.). 2016 08;594(15):4095-6.

 

Last Updated: 31 Dec 1969

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Generation of human induced pluripotent stem cell line from a patient with a long QT syndrome type 2.
 

Author(s): Azra Fatima, Dina Ivanyuk, Stefan Herms, Stefanie Heilmann-Heimbach, Orla O'Shea, Charlotte Chapman, Zsuszanna Izsvák, Martin Farr, Jürgen Hescheler, Tomo Šarić

Journal: Stem Cell Res. 2016 Mar;16(2):304-7.

 

We report here the generation of human iPS cell line UKKi009-A from dermal fibroblasts of a patient carrying heterozygous mutation c.3035-3045delTCCCTCGATGC, p.Leu1012Pro (fs*55) in KCNH2 gene leading to long QT syndrome type 2 (LQT2). We used the Sleeping Beauty transposon-based ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Long QT syndrome 2" returned 1 free, full-text review articles on human participants. First 3 results:

A Tale of 2 Diseases: The History of Long-QT Syndrome and Brugada Syndrome.
 

Author(s): Ofer Havakuk, Sami Viskin

Journal: J. Am. Coll. Cardiol.. 2016 Jan;67(1):100-8.

 

The Brugada syndrome (BrS) and long-QT syndrome (LQTS) present as congenital or acquired disorders with diagnostic electrocardiograms (ST-segment elevation and prolonged QT interval, respectively) and increased risk for malignant arrhythmias. Our understanding of the 2 disease forms ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients
 

Status: Recruiting

Condition Summary: Long QT Syndrome Type 1 or 2

 

Last Updated: 4 Oct 2016

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