Lyme disease

Common Name(s)

Lyme disease

Lyme disease is an infection caused by three types of Borrellia bacteria. One type is most common in the United States, while the other two types are more common in Europe and Asia. These bacteria are carried by certain ticks; in the United States most commonly the deer tick, in Europe the sheep tick, and in China the taiga tick. An infected tick can pass the bacteria to humans (and other animals) through its bites. However, the transfer of bacteria is believed to only begin after 36-48 hours of the tick being attached.

A characteristic circular rash often develops around the tick bite within 3-30 days and is diagnostic, meaning treatment should begin immediately. Sometimes the rash appears like a bull’s-eye, other times it is a solid red patch, and sometimes the rash does not occur exactly at the site of the tick bite. Other early symptoms include flu like symptoms such as fever, chills, and body aches. Laboratory blood tests are not considered reliable until at least one month after becoming infected through a tick bite. Therefore, it is important if you have flu like symptoms with or without a rash to let your doctor know you have been bitten by a tick within a month’s time.

As symptoms progress, an individual may have a stiff neck, severe fatigue, tingling sensation in the hands or feet, or facial paralysis. Left untreated, later symptoms may involve the joints, heart, and central nervous system. In most cases, the infection and its symptoms are eliminated by antibiotics, especially if the illness is treated early. Delayed or inadequate treatment can lead to more serious symptoms, which can be disabling and difficult to treat. If you or a family member has been diagnosed with Lyme disease, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme disease" for support, advocacy or research.

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American Lyme Disease Foundation

The American Lyme Disease Foundation, Inc. is dedicated to the prevention, diagnosis and treatment of Lyme disease. The Foundation plays a key role in providing reliable and scientifically accurate information to the public, medical community and government agencies about Lyme disease and its effects on human health and quality of life.

Last Updated: 7 Jan 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme disease" for support, advocacy or research.

Logo
American Lyme Disease Foundation

The American Lyme Disease Foundation, Inc. is dedicated to the prevention, diagnosis and treatment of Lyme disease. The Foundation plays a key role in providing reliable and scientifically accurate information to the public, medical community and government agencies about Lyme disease and its effects on human health and quality of life.

http://www.aldf.com

Last Updated: 7 Jan 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lyme disease" returned 696 free, full-text research articles on human participants. First 3 results:

Infection history of the blood-meal host dictates pathogenic potential of the Lyme disease spirochete within the feeding tick vector.
 

Author(s): Bharti Bhatia, Chad Hillman, Valentina Carracoi, Britney N Cheff, Kit Tilly, Patricia A Rosa

Journal:

 

Lyme disease in humans is caused by several genospecies of the Borrelia burgdorferi sensu lato (s.l.) complex of spirochetal bacteria, including B. burgdorferi, B. afzelii and B. garinii. These bacteria exist in nature as obligate parasites in an enzootic cycle between small vertebrate ...

Last Updated: 31 Dec 1969

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Cost-effectiveness of longer-term versus shorter-term provision of antibiotics in patients with persistent symptoms attributed to Lyme disease.
 

Author(s): Anneleen Berende, Lisette Nieuwenhuis, Hadewych J M Ter Hofstede, Fidel J Vos, Michiel L Vogelaar, Mirjam Tromp, Henriët van Middendorp, A Rogier T Donders, Andrea W M Evers, Bart Jan Kullberg, Eddy M M Adang

Journal:

 

The treatment of persistent symptoms attributed to Lyme disease remains controversial. Recently, the PLEASE study did not demonstrate any additional clinical benefit of longer-term versus shorter-term antibiotic treatment. However, the economic impact of the antibiotic strategies ...

Last Updated: 31 Dec 1969

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[Lyme disease or not ?]
 

Author(s): A Salmon, A de Noordhout Maertens, F Moerman

Journal: Rev Med Liege. 2018 Mar;73(3):129-134.

 

Lyme disease is a complex pathology due to an infection by a spirochaete from the genus Borrelia. This infection results from a tick bite lasting more than 24 hours. Signs and symptoms are numerous and are usually classified in three stages: early localized disease, early disseminated ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lyme disease" returned 76 free, full-text review articles on human participants. First 3 results:

When a patient suspected with juvenile idiopathic arthritis turns out to be diagnosed with an infectious disease - a review of Lyme arthritis in children.
 

Author(s): Krzysztof Orczyk, Joanna Świdrowska-Jaros, Elżbieta Smolewska

Journal:

 

The Lyme arthritis is a common manifestation of infection with Borrelia burgdorferi spirochete. Despite its infectious background, the inflammation clinically and histopatologically resembles juvenile idiopathic arthritis. As it affects a considerable number of Lyme disease patients, ...

Last Updated: 31 Dec 1969

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Lyme disease ecology in a changing world: consensus, uncertainty and critical gaps for improving control.
 

Author(s): A Marm Kilpatrick, Andrew D M Dobson, Taal Levi, Daniel J Salkeld, Andrea Swei, Howard S Ginsberg, Anne Kjemtrup, Kerry A Padgett, Per M Jensen, Durland Fish, Nick H Ogden, Maria A Diuk-Wasser

Journal: Philos. Trans. R. Soc. Lond., B, Biol. Sci.. 2017 Jun;372(1722):.

 

Lyme disease is the most common tick-borne disease in temperate regions of North America, Europe and Asia, and the number of reported cases has increased in many regions as landscapes have been altered. Although there has been extensive work on the ecology and epidemiology of this ...

Last Updated: 31 Dec 1969

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Interferon-γ-induced protein 10 in Lyme disease.
 

Author(s): P Fallahi, G Elia, A Bonatti

Journal: Clin Ter. ;168(2):e146-e150.

 

Lyme disease is an infectious disease caused by bacteria of the Borrelia type, that affects about 300,000 people a year in the USA and 65,000 people a year in Europe. Borrelia infection, and Lyme disease, following occupational exposure has been frequently reported in USA, Europe ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Xenodiagnosis After Antibiotic Treatment for Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 14 Aug 2018

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Detection of Borrelia Bacteria in Early Stage Lyme Borreliosis Using the T2Lyme Panel
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 15 Aug 2018

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Evaluation, Treatment, and Follow-up of Patients With Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 8 Aug 2018

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