Middle East respiratory syndrome

Common Name(s)

Middle East respiratory syndrome, MERS

Middle East respiratory syndrome (MERS) is a respiratory illness caused by the MERS-CoV virus. The respiratory tract includes the nose, sinuses, and lungs, as well as many other important structures the body uses to breathe. The first case of MERS was seen in Saudi Arabia, and there have been many reported cases in the countries within and nearby the Arabian Peninsula.

Symptoms of MERS may include fever, chills, cough, trouble breathing, body aches, diarrhea, vomiting, and an upset stomach. Though uncommon, there have been some cases where individuals who are infected with the virus display only very mild or no symptoms. Severe complications may include a rapid deterioration of respiratory function (acute respiratory distress syndrome) and pneumonia. Higher risk individuals that are more likely to become infected include older individuals, those who tend to get sick frequently, pregnant women, children, and those with other long-term diseases such as cancer or diabetes.

The Center for Disease Control (CDC) believes the virus originated from an animal source, most likely from camels. Additionally, scientists believe the disease is spread person to person through close contact. However, since many qualities of the virus are not known at this time, further research needs to be completed to fully understand the origin and transmission of the virus.

Ways to prevent becoming infected by the MERS virus include thorough and frequent washing of the hands; avoid touching of the eyes, nose, and mouth; and to avoid contact with individuals who may have been infected or are displaying symptoms. If you or a family member has had possible exposure to the virus and are experiencing symptoms, contact a medical professional as soon as possible to talk about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Middle East respiratory syndrome" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Middle East respiratory syndrome" returned 323 free, full-text research articles on human participants. First 3 results:

A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV.
 

Author(s): Guangyu Zhao, Lei He, Shihui Sun, Hongjie Qiu, Wanbo Tai, Jiawei Chen, Jiangfan Li, Yuehong Chen, Yan Guo, Yufei Wang, Jian Shang, Kaiyuan Ji, Ruiwen Fan, Enqi Du, Shibo Jiang, Fang Li, Lanying Du, Yusen Zhou

Journal:

 

The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) continues to infect humans and camels, calling for efficient, cost-effective, and broad-spectrum strategies to control its spread. Nanobodies (Nbs) are single-domain antibodies derived from camelids and sharks ...

Last Updated: 31 Dec 1969

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Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus.
 

Author(s): Wei-Chen Hsin, Chan-Hua Chang, Chi-You Chang, Wei-Hao Peng, Chung-Liang Chien, Ming-Fu Chang, Shin C Chang

Journal:

 

Middle East respiratory syndrome coronavirus (MERS-CoV) consists of a positive-sense, single-stranded RNA genome and four structural proteins: the spike, envelope, membrane, and nucleocapsid protein. The assembly of the viral genome into virus particles involves viral structural proteins ...

Last Updated: 31 Dec 1969

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Asymptomatic Middle East Respiratory Syndrome coronavirus infection using a serologic survey in Korea.
 

Author(s): Yeong-Jun Song, Jeong-Sun Yang, Hee Jung Yoon, Hae-Sung Nam, Soon Young Lee, Hae-Kwan Cheong, Woo-Jung Park, Sung Han Park, Bo Youl Choi, Sung Soon Kim, Moran Ki

Journal:

 

The rates of asymptomatic infection with Middle East Respiratory Syndrome (MERS) coronavirus vary. A serologic study was conducted to determine the asymptomatic MERS infection rate in healthcare workers and non-healthcare workers by exposure status.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Middle East respiratory syndrome" returned 34 free, full-text review articles on human participants. First 3 results:

An Opportunistic Pathogen Afforded Ample Opportunities: Middle East Respiratory Syndrome Coronavirus.
 

Author(s): Ian M Mackay, Katherine E Arden

Journal:

 

The human coronaviruses (CoV) include HCoV-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1, some of which have been known for decades. The severe acute respiratory syndrome (SARS) CoV briefly emerged into the human population but was controlled. In 2012, another novel severely human pathogenic ...

Last Updated: 31 Dec 1969

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Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): A review.
 

Author(s): Sabeena Mustafa, Hanan Balkhy, Musa N Gabere

Journal: J Infect Public Health. ;11(1):9-17.

 

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a highly pathogenic respiratory virus with mechanisms that may be driven by innate immune responses. Despite the effort of scientific studies related to this virus, Middle East Respiratory Syndrome (MERS) is still a public ...

Last Updated: 31 Dec 1969

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Elucidating Transmission Patterns From Internet Reports: Ebola and Middle East Respiratory Syndrome as Case Studies.
 

Author(s): Gerardo Chowell, Julie M Cleaton, Cecile Viboud

Journal: J. Infect. Dis.. 2016 12;214(suppl_4):S421-S426.

 

The paucity of traditional epidemiological data during epidemic emergencies calls for alternative data streams to characterize the key features of an outbreak, including the nature of risky exposures, the reproduction number, and transmission heterogeneities. We illustrate the potential ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Immunogenicity of a Candidate MERS-CoV Vaccine (MERS001)
 

Status: Recruiting

Condition Summary: MERS (Middle East Respiratory Syndrome)

 

Last Updated: 5 Jun 2018

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MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b
 

Status: Recruiting

Condition Summary: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

 

Last Updated: 2 Nov 2017

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