Middle East respiratory syndrome

Common Name(s)

Middle East respiratory syndrome, MERS

Middle East respiratory syndrome (MERS) is a respiratory illness caused by the MERS-CoV virus. The respiratory tract includes the nose, sinuses, and lungs, as well as many other important structures the body uses to breathe. The first case of MERS was seen in Saudi Arabia, and there have been many reported cases in the countries within and nearby the Arabian Peninsula.

Symptoms of MERS may include fever, chills, cough, trouble breathing, body aches, diarrhea, vomiting, and an upset stomach. Though uncommon, there have been some cases where individuals who are infected with the virus display only very mild or no symptoms. Severe complications may include a rapid deterioration of respiratory function (acute respiratory distress syndrome) and pneumonia. Higher risk individuals that are more likely to become infected include older individuals, those who tend to get sick frequently, pregnant women, children, and those with other long-term diseases such as cancer or diabetes.

The Center for Disease Control (CDC) believes the virus originated from an animal source, most likely from camels. Additionally, scientists believe the disease is spread person to person through close contact. However, since many qualities of the virus are not known at this time, further research needs to be completed to fully understand the origin and transmission of the virus.

Ways to prevent becoming infected by the MERS virus include thorough and frequent washing of the hands; avoid touching of the eyes, nose, and mouth; and to avoid contact with individuals who may have been infected or are displaying symptoms. If you or a family member has had possible exposure to the virus and are experiencing symptoms, contact a medical professional as soon as possible to talk about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Middle East respiratory syndrome" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Middle East respiratory syndrome" returned 272 free, full-text research articles on human participants. First 3 results:

Occurrence of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) across the Gulf Corporation Council countries: Four years update.
 

Author(s): Mahmoud Aly, Mohamed Elrobh, Maha Alzayer, Sameera Aljuhani, Hanan Balkhy

Journal:

 

The emergence of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections has become a global issue of dire concerns. MERS-CoV infections have been identified in many countries all over the world whereas high level occurrences have been documented in the Middle East ...

Last Updated: 13 Oct 2017

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Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula.
 

Author(s): Oyelola A Adegboye, Ezra Gayawan, Fahad Hanna

Journal:

 

Middle East respiratory syndrome coronavirus is a contagious respiratory pathogen that is contracted via close contact with an infected subject. Transmission of the pathogen has occurred through animal-to-human contact at first followed by human-to-human contact within families and ...

Last Updated: 31 Jul 2017

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Crystal structure of Middle East respiratory syndrome coronavirus helicase.
 

Author(s): Wei Hao, Justyna Aleksandra Wojdyla, Rong Zhao, Ruiyun Han, Rajat Das, Ivan Zlatev, Muthiah Manoharan, Meitian Wang, Sheng Cui

Journal:

 

Middle East respiratory syndrome coronavirus (MERS-CoV) remains a threat to public health worldwide; however, effective vaccine or drug against CoVs remains unavailable. CoV helicase is one of the three evolutionary most conserved proteins in nidoviruses, thus making it an important ...

Last Updated: 26 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Middle East respiratory syndrome" returned 28 free, full-text review articles on human participants. First 3 results:

Middle East respiratory syndrome in children. Dental considerations.
 

Author(s): Fares S Al-Sehaibany

Journal: Saudi Med J. 2017 Apr;38(4):339-343.

 

As of January 2016, 1,633 laboratory-confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and 587 MERS-related deaths have been reported by the World Health Organization globally. Middle East Respiratory Syndrome Coronavirus  may occur sporadically ...

Last Updated: 11 Apr 2017

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Clinical determinants of the severity of Middle East respiratory syndrome (MERS): a systematic review and meta-analysis.
 

Author(s): Ryota Matsuyama, Hiroshi Nishiura, Satoshi Kutsuna, Kayoko Hayakawa, Norio Ohmagari

Journal:

 

While the risk of severe complications of Middle East respiratory syndrome (MERS) and its determinants have been explored in previous studies, a systematic analysis of published articles with different designs and populations has yet to be conducted. The present study aimed to systematically ...

Last Updated: 30 Nov 2016

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Assessment of the risk posed to Singapore by the 2015 Middle East respiratory syndrome outbreak in the Republic of Korea.
 

Author(s): Emma Xuxiao Zhang, Olivia Seen Huey Oh, Wanhan See, Pream Raj, Lyn James, Kamran Khan, Jeannie Su Hui Tey

Journal:

 

To assess the public health risk to Singapore posed by the Middle East respiratory syndrome (MERS) outbreak in the Republic of Korea in 2015.

Last Updated: 10 Aug 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b
 

Status: Recruiting

Condition Summary: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

 

Last Updated: 2 Nov 2017

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