Macular Dystrophy

Common Name(s)

Macular Dystrophy

Macular dystrophy is a genetic eye disorder that causes vision loss. It causes damage to the area of the eye called the macula, which is responsible for central vision. When the macula is damaged, people have trouble seeing straight ahead. Vision becomes blurry and distorted. However, side (peripheral) vision is not affected. Vision slowly worsens over time. Unfortunately, there is no treatment available for macular dystrophy at this time. However, promising new research is currently being conducted.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular Dystrophy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Macular Dystrophy" returned 158 free, full-text research articles on human participants. First 3 results:

Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy.
 

Author(s): Karlos Ítalo Viana, André Messias, Rubens Camargo Siqueira, Murilo W Rodrigues, Rodrigo Jorge

Journal: Arq Bras Oftalmol. ;80(2):118-121.

 

We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive ...

Last Updated: 31 Dec 1969

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Cone dystrophy or macular dystrophy associated with novel autosomal dominantmutations.
 

Author(s): Gaël Manes, Sonia Mamouni, Emilie Hérald, Anne-Claire Richard, Audrey Sénéchal, Karim Aouad, Béatrice Bocquet, Isabelle Meunier, Christian P Hamel

Journal:

 

Sixteen different mutations in the guanylate cyclase activator 1A gene (), have been previously identified to cause autosomal dominant cone dystrophy (adCOD), cone-rod dystrophy (adCORD), macular dystrophy (adMD), and in an isolated patient, retinitis pigmentosa (RP). The purpose ...

Last Updated: 31 Dec 1969

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Hypotrichosis with juvenile macular dystrophy: a case report with molecular study.
 

Author(s): Lucas Perez Vicente, Simone Finzi, Remo Susanna, Terri L Young

Journal: Arq Bras Oftalmol. ;80(1):49-51.

 

Hypotrichosis with juvenile macular dystrophy is a rare autosomal recessive disorder characterized by sparse scalp hair caused by hair follicle abnormalities as well as progressive retinal degeneration leading to blindness in the second or third decade of life. It is associated with ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Macular Dystrophy" returned 3 free, full-text review articles on human participants. First 3 results:

Macular pattern dystrophy and homonymous hemianopia in MELAS syndrome.
 

Author(s): Radua Kamal-Salah, Isabel Baquero-Aranda, María Del Mar Grana-Pérez, Jose Manuel García-Campos

Journal:

 

We report an unusual association of a pattern dystrophy of the retinal pigment epithelium and homonymous hemianopia in a woman diagnosed with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome.

Last Updated: 31 Dec 1969

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Macular dystrophy associated with the mitochondrial DNA A3243G mutation: pericentral pigment deposits or atrophy? Report of two cases and review of the literature.
 

Author(s): Alejandra Daruich, Alexandre Matet, François-Xavier Borruat

Journal:

 

The A3243G point mutation in mitochondrial DNA (mtDNA) is associated with MELAS (mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes) and MIDD syndromes (maternally inherited diabetes and deafness). Both MELAS and MIDD patients can present with visual symptoms ...

Last Updated: 31 Dec 1969

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Macular corneal dystrophy. Studies of sulfated glycosaminoglycans in corneal explant and confluent stromal cell cultures.
 

Author(s): G K Klintworth, C F Smith

Journal: Am. J. Pathol.. 1977 Oct;89(1):167-82.

 

The inherited disorder macular corneal dystrophy (MCD), a localized corneal mucopolysaccharidosis, is currently thought to result from an inability to catabolize corneal keratan sulfate (keratan sulfate 1). As studies on isolated cells have provided insight into metabolic abnormalities ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a Simulator
 

Status: Not yet recruiting

Condition Summary: Age-related Macular Degeneration

 

Last Updated: 5 Feb 2018

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Evaluation the Pharmacokinetics, Safety, Tolerability of TK001 in Patients With Neovascular Age-related Macular Degeneration
 

Status: Recruiting

Condition Summary: Neovascular Age-related Macular Degeneration

 

Last Updated: 15 Aug 2017

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