Macular degeneration

Common Name(s)

Macular degeneration

Age-Related Macular Degeneration (AMD) is a common eye condition which causes vision loss that gets worse over time (progressive). The disorder causes damage to the macula, which is the center of the back of the eye (retina). This area helps a person see fine details and perform tasks, such as reading and driving (sharp central vision). AMD is the leading cause of vision loss in adults.

Vision loss caused by AMD usually only affects the center of the eye, allowing affected people to recognize objects on the edges of their vision (peripheral vision). Some cases of AMD cause total blindness. The progression of the disease is painless, making it difficult for affected people to notice that their vision is getting worse until the vision loss is severe. There are 2 major types of AMD: wet AMD and dry AMD. 90% of all cases of AMD are "dry," resulting in slow and gradual vision loss, while the wet form can cause severe and rapid vision loss. Additional information about each form is available in separate description entries.

The cause of AMD is still unclear. Age and genetics are the two most significant risk factors. AMD is usually found in adults over 55 and the risk increases with age. Females are more likely to develop the condition. Smoking also significantly increases the chances of developing the disorder. AMD is usually diagnosed by an eye doctor (ophthalmologist) who uses both a routine eye exam and special eye tests, such as optical coherence tomography (OCT), to look at images of the retina. There is no cure for AMD, but good nutrition and protection from UV rays can help slow or prevent symptoms. If you or a loved one has been diagnosed with AMD, talk with a doctor about current treatment options. Support groups can provide additional information and connect you with other families affected by AMD.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular degeneration" for support, advocacy or research.

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Association for Macular Diseases, Inc.

The Association for Macular Diseases, Inc. acts as a nationwide support group for individuals and their families endeavoring to adjust to the restrictions and changes brought about by macular disease.

Last Updated: 2 Jun 2010

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Macular Degeneration Support

The mission of MD Support is to provide information, support and advocacy for people affected by macular degeneration and similar diseases of the retina leading to central vision loss.

Last Updated: 3 Jan 2013

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Vision Research ROPARD Foundation

The Mission of the Vision Research ROPARD Foundation is to support research, programs and services designed to prevent, treat and/or provide adaptive resources to patients of all ages and their family members affected by vision threatening retinal disease. We carry out this mission through clinically relevant research, educational programs for patients, family members and general public, physician educational programs, and community support programs; such as, the Children’s Low Vision Resource Center.

Last Updated: 15 May 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular degeneration" for support, advocacy or research.

Logo
Association for Macular Diseases, Inc.

The Association for Macular Diseases, Inc. acts as a nationwide support group for individuals and their families endeavoring to adjust to the restrictions and changes brought about by macular disease.

Last Updated: 2 Jun 2010

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Macular Degeneration Support

The mission of MD Support is to provide information, support and advocacy for people affected by macular degeneration and similar diseases of the retina leading to central vision loss.

http://www.mdsupport.org

Last Updated: 3 Jan 2013

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Vision Research ROPARD Foundation

The Mission of the Vision Research ROPARD Foundation is to support research, programs and services designed to prevent, treat and/or provide adaptive resources to patients of all ages and their family members affected by vision threatening retinal disease. We carry out this mission through clinically relevant research, educational programs for patients, family members and general public, physician educational programs, and community support programs; such as, the Children’s Low Vision Resource Center.

http://www.ropard.org

Last Updated: 15 May 2015

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General Support Organizations

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General Resources

Resource links directories

Links to organizations, agencies, hospitals, and commercial distributors of low vision products and services.

Updated 3 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Macular degeneration" returned 1613 free, full-text research articles on human participants. First 3 results:

Fully Automated Robust System to Detect Retinal Edema, Central Serous Chorioretinopathy, and Age Related Macular Degeneration from Optical Coherence Tomography Images.
 

Author(s): Samina Khalid, M Usman Akram, Taimur Hassan, Ammara Nasim, Amina Jameel

Journal: Biomed Res Int. 2017 ;2017():7148245.

 

Maculopathy is the excessive damage to macula that leads to blindness. It mostly occurs due to retinal edema (RE), central serous chorioretinopathy (CSCR), or age related macular degeneration (ARMD). Optical coherence tomography (OCT) imaging is the latest eye testing technique that ...

Last Updated: 20 Apr 2017

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The association between periodontal disease and age-related macular degeneration in the Korea National health and nutrition examination survey: A cross-sectional observational study.
 

Author(s): Yong Un Shin, Han Woong Lim, Eun Hee Hong, Min Ho Kang, Mincheol Seong, Eunwoo Nam, Heeyoon Cho

Journal: Medicine (Baltimore). 2017 Apr;96(14):e6418.

 

Periodontal disease (PD) is associated with various systemic diseases. We investigated the association between PD and age-related macular degeneration (AMD).For this population-based, cross-sectional study, we enrolled 13,072 adults at least 40 years of age with gradable retinal fundus ...

Last Updated: 6 Apr 2017

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Effect of topical isopropyl unoprostone on macular atrophy progression in eyes with exudative age-related macular degeneration.
 

Author(s): Chieko Shiragami, Masahiro Miyake, Atsushi Fujiwara, Yuki Morizane, Akitaka Tsujikawa, Ayana Yamashita, Fumio Shiraga

Journal: Medicine (Baltimore). 2017 Mar;96(12):e6422.

 

To evaluate the efficacy and safety of topical isopropyl unoprostone (IU) in treating macular atrophy in age-related macular degeneration (AMD) patients.

Last Updated: 22 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Macular degeneration" returned 271 free, full-text review articles on human participants. First 3 results:

miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD).
 

Author(s): John Paul SanGiovanni, Peter M SanGiovanni, Przemysław Sapieha, Vincent De Guire

Journal: Clin. Chem. Lab. Med.. 2017 May;55(5):763-775.

 

Advanced age-related macular degeneration (AAMD) is a complex sight-threating disease of public health significance. Micro RNAs (miRNAs) have been proposed as biomarkers for AAMD. The presence of certain single nucleotide polymorphisms (SNPs) may influence the explanatory value of ...

Last Updated: 26 Mar 2017

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The Use of Microperimetry to Detect Functional Progression in Non-Neovascular Age-Related Macular Degeneration: A Systematic Review.
 

Author(s): Evan N Wong, Avenell L Chew, William H Morgan, Praveen J Patel, Fred K Chen

Journal: Asia Pac J Ophthalmol (Phila). ;6(1):70-79.

 

We reviewed the current literature on the ability of microperimetry to detect non-neovascular age-related macular degeneration (AMD) disease progression. The index test was retinal sensitivity measurement assessed by microperimetry and comparators were other functional measures (best-corrected ...

Last Updated: 5 Feb 2017

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Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review.
 

Author(s): Ângela Carneiro, José Paulo Andrade

Journal: Oxid Med Cell Longev. 2017 ;2017():6469138.

 

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. In this narrative review, we will summarize the nutritional interventions evaluated in numerous observational studies and a few randomized clinical trials. The AREDS and AREDS2 studies ...

Last Updated: 3 Feb 2017

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal
 

Status: Recruiting

Condition Summary: Age-Related Macular Degeneration

 

Last Updated: 19 Sep 2016

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Last Updated: 4 Oct 2016

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