Macular degeneration

Common Name(s)

Macular degeneration

Age-Related Macular Degeneration (AMD) is a common eye condition which causes vision loss that gets worse over time (progressive). The disorder causes damage to the macula, which is the center of the back of the eye (retina). This area helps a person see fine details and perform tasks, such as reading and driving (sharp central vision). AMD is the leading cause of vision loss in adults.

Vision loss caused by AMD usually only affects the center of the eye, allowing affected people to recognize objects on the edges of their vision (peripheral vision). Some cases of AMD cause total blindness. The progression of the disease is painless, making it difficult for affected people to notice that their vision is getting worse until the vision loss is severe. There are 2 major types of AMD: wet AMD and dry AMD. 90% of all cases of AMD are "dry," resulting in slow and gradual vision loss, while the wet form can cause severe and rapid vision loss. Additional information about each form is available in separate description entries.

The cause of AMD is still unclear. Age and genetics are the two most significant risk factors. AMD is usually found in adults over 55 and the risk increases with age. Females are more likely to develop the condition. Smoking also significantly increases the chances of developing the disorder. AMD is usually diagnosed by an eye doctor (ophthalmologist) who uses both a routine eye exam and special eye tests, such as optical coherence tomography (OCT), to look at images of the retina. There is no cure for AMD, but good nutrition and protection from UV rays can help slow or prevent symptoms. If you or a loved one has been diagnosed with AMD, talk with a doctor about current treatment options. Support groups can provide additional information and connect you with other families affected by AMD.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular degeneration" for support, advocacy or research.

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Association for Macular Diseases, Inc.

The Association for Macular Diseases, Inc. acts as a nationwide support group for individuals and their families endeavoring to adjust to the restrictions and changes brought about by macular disease.

Last Updated: 2 Jun 2010

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Macular Degeneration Support

The mission of MD Support is to provide information, support and advocacy for people affected by macular degeneration and similar diseases of the retina leading to central vision loss.

Last Updated: 3 Jan 2013

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Vision Research ROPARD Foundation

The Mission of the Vision Research ROPARD Foundation is to support research, programs and services designed to prevent, treat and/or provide adaptive resources to patients of all ages and their family members affected by vision threatening retinal disease. We carry out this mission through clinically relevant research, educational programs for patients, family members and general public, physician educational programs, and community support programs; such as, the Children’s Low Vision Resource Center.

Last Updated: 15 May 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular degeneration" for support, advocacy or research.

Logo
Association for Macular Diseases, Inc.

The Association for Macular Diseases, Inc. acts as a nationwide support group for individuals and their families endeavoring to adjust to the restrictions and changes brought about by macular disease.

Last Updated: 2 Jun 2010

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Macular Degeneration Support

The mission of MD Support is to provide information, support and advocacy for people affected by macular degeneration and similar diseases of the retina leading to central vision loss.

http://www.mdsupport.org

Last Updated: 3 Jan 2013

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Vision Research ROPARD Foundation

The Mission of the Vision Research ROPARD Foundation is to support research, programs and services designed to prevent, treat and/or provide adaptive resources to patients of all ages and their family members affected by vision threatening retinal disease. We carry out this mission through clinically relevant research, educational programs for patients, family members and general public, physician educational programs, and community support programs; such as, the Children’s Low Vision Resource Center.

http://www.ropard.org

Last Updated: 15 May 2015

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General Support Organizations

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General Resources

Resource links directories

Links to organizations, agencies, hospitals, and commercial distributors of low vision products and services.

Updated 3 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Macular degeneration" returned 1779 free, full-text research articles on human participants. First 3 results:

Influence of vitreomacular interface on anti-vascular endothelial growth factor treatment outcomes in neovascular age-related macular degeneration: A MOOSE-compliant meta-analysis.
 

Author(s): Meng Gao, LiMei Liu, XiDa Liang, YanPing Yu, XinXin Liu, Wu Liu

Journal: Medicine (Baltimore). 2017 Dec;96(50):e9345.

 

The aim of the study was to evaluate the influence of vitreomacular interface configuration on treatment outcomes after intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy for neovascular age-related macular degeneration (AMD).The Pubmed, Embase, and Cochrane ...

Last Updated: 31 Dec 1969

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Influence of new societal factors on neovascular age-related macular degeneration outcomes.
 

Author(s): Audrey Giocanti-Aurégan, Elige Chbat, Adil Darugar, Christophe Morel, Bruno Morin, John Conrath, François Devin

Journal:

 

To assess the impact of unstudied societal factors for neovascular age-related macular degeneration (nAMD) on functional outcomes after anti-VEGFs.

Last Updated: 31 Dec 1969

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Risk of macular degeneration affected by polymorphisms in Matrix metalloproteinase-2: A case-control study in Chinese Han population.
 

Author(s): Jie Cheng, Xiaolin Hao, Zhongchen Zhang

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8190.

 

The purpose of this study was to investigate the correlation of single nucleotide polymorphisms (SNPs) in Matrix metalloproteinase -2 (MMP-2) gene and the risk of age-related macular degeneration (AMD) in Chinese Han population.A total of 126 AMD patients and 141 healthy controls ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Macular degeneration" returned 311 free, full-text review articles on human participants. First 3 results:

Prevention of Age-Related Macular Degeneration.
 

Author(s): Niharika Singh, Sangeetha Srinivasan, Vinata Muralidharan, Rupak Roy, Jayprakash V, Rajiv Raman

Journal: Asia Pac J Ophthalmol (Phila). ;6(6):520-526.

 

Age-related macular degeneration (AMD) compromises quality of life. However, the available therapeutic options are limited. This has led to the identification of modifiable risk factors to prevent the development or alter the natural course and prognosis of AMD. The identification ...

Last Updated: 31 Dec 1969

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Effects of Aflibercept for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Observational Comparative Studies.
 

Author(s): Yan Zhang, Catherine Chioreso, Marin L Schweizer, Michael D Abràmoff

Journal: Invest. Ophthalmol. Vis. Sci.. 2017 Nov;58(13):5616-5627.

 

To compare the effects of aflibercept and other anti-vascular endothelial growth factor (anti-VEGF) medications on both functional and anatomical outcomes for treatment-naïve neovascular age-related macular degeneration (nAMD) in the real world.

Last Updated: 31 Dec 1969

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New Treatment Modalities for Neovascular Age-Related Macular Degeneration.
 

Author(s): Patricio G Schlottmann, Arturo A Alezzandrini, Marcelo Zas, Francisco J Rodriguez, José D Luna, Lihteh Wu

Journal: Asia Pac J Ophthalmol (Phila). ;6(6):514-519.

 

Age-related macular degeneration (AMD) is considered one of the main causes of severe vision loss in older adults. The neovascular form (nAMD) is an advanced stage, which is responsible for the most severe vision loss. Vascular endothelial growth factor (VEGF) is at present the main ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a Simulator
 

Status: Not yet recruiting

Condition Summary: Age-related Macular Degeneration

 

Last Updated: 5 Feb 2018

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Last Updated: 24 Jan 2018

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