Malaria

Common Name(s)

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malaria" returned 9932 free, full-text research articles on human participants. First 3 results:

The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria.
 

Author(s): Christopher P Karch, Tais A P F Doll, Sara M Paulillo, Issa Nebie, David E Lanar, Giampietro Corradin, Peter Burkhard

Journal:

 

The parasitic disease malaria remains a major global public health concern and no truly effective vaccine exists. One approach to the development of a malaria vaccine is to target the asexual blood stage that results in clinical symptoms. Most attempts have failed. New antigens such ...

Last Updated: 7 Sep 2017

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Unsupervised primaquine for the treatment of Plasmodium vivax malaria relapses in southern Papua: A hospital-based cohort study.
 

Author(s): Nicholas M Douglas, Jeanne Rini Poespoprodjo, Dewi Patriani, Michael J Malloy, Enny Kenangalem, Paulus Sugiarto, Julie A Simpson, Yati Soenarto, Nicholas M Anstey, Ric N Price

Journal:

 

Primaquine is the only licensed drug for eradicating Plasmodium vivax hypnozoites and, therefore, preventing relapses of vivax malaria. It is a vital component of global malaria elimination efforts. Primaquine is efficacious when supervised in clinical trials, but its effectiveness ...

Last Updated: 29 Aug 2017

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Malaria, malnutrition, and birthweight: A meta-analysis using individual participant data.
 

Author(s): Jordan E Cates, Holger W Unger, Valerie Briand, Nadine Fievet, Innocent Valea, Halidou Tinto, Umberto D'Alessandro, Sarah H Landis, Seth Adu-Afarwuah, Kathryn G Dewey, Feiko O Ter Kuile, Meghna Desai, Stephanie Dellicour, Peter Ouma, Julie Gutman, Martina Oneko, Laurence Slutsker, Dianne J Terlouw, Simon Kariuki, John Ayisi, Mwayiwawo Madanitsa, Victor Mwapasa, Per Ashorn, Kenneth Maleta, Ivo Mueller, Danielle Stanisic, Christentze Schmiegelow, John P A Lusingu, Anna Maria van Eijk, Melissa Bauserman, Linda Adair, Stephen R Cole, Daniel Westreich, Steven Meshnick, Stephen Rogerson

Journal:

 

Four studies previously indicated that the effect of malaria infection during pregnancy on the risk of low birthweight (LBW; <2,500 g) may depend upon maternal nutritional status. We investigated this dependence further using a large, diverse study population.

Last Updated: 9 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malaria" returned 986 free, full-text review articles on human participants. First 3 results:

A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria.
 

Author(s): Gunanidhi Dhangadamajhi, Avishek Kar, Ronnaly Rout, Prabin Dhangadamajhi

Journal: Rev. Soc. Bras. Med. Trop.. ;50(2):153-160.

 

Toll-like receptors (TLRs) are critical mediators of the inflammatory response to malarial infection, and gene polymorphisms affecting TLR function may be partially responsible for inter-individual variation in disease manifestation. However, there are inconsistencies in the associations ...

Last Updated: 31 May 2017

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Malaria elimination in Lao PDR: the challenges associated with population mobility.
 

Author(s): Sengchanh Kounnavong, Deyer Gopinath, Bouasy Hongvanthong, Chanthalone Khamkong, Odai Sichanthongthip

Journal:

 

Although the Lao People's Democratic Republic (Lao PDR) is comparatively small landlocked country with patterns of both in- and out-migration, its human migration situation has been poorly studied. This is despite all of the country's 18 provinces sharing both official and unofficial ...

Last Updated: 25 Apr 2017

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Defining micro-epidemiology for malaria elimination: systematic review and meta-analysis.
 

Author(s): Melanie Bannister-Tyrrell, Kristien Verdonck, Susanna Hausmann-Muela, Charlotte Gryseels, Joan Muela Ribera, Koen Peeters Grietens

Journal:

 

Malaria risk can vary markedly between households in the same village, or between villages, but the determinants of this "micro-epidemiological" variation in malaria risk remain poorly understood. This study aimed to identify factors that explain fine-scale variation in malaria risk ...

Last Updated: 21 Apr 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Rosiglitazone Adjunctive Therapy for Severe Malaria in Children
 

Status: Recruiting

Condition Summary: Malaria

 

Last Updated: 7 Jul 2016

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Last Updated: 2 Feb 2017

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