Malaria

Common Name(s)

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
 

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Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malaria" returned 9956 free, full-text research articles on human participants. First 3 results:

Therapeutic efficacy and effects of artemisinin-based combination treatments on uncomplicated Plasmodium falciparum malaria -associated anaemia in Nigerian children during seven years of adoption as first-line treatments.
 

Author(s): Akintunde Sowunmi, Kazeem Akano, Godwin Ntadom, Adejumoke I Ayede, Folasade O Ibironke, Temitope Aderoyeje, Elsie O Adewoye, Bayo Fatunmbi, Stephen Oguche, Henrietta U Okafor, Ismaila Watila, Martin Meremikwu, Philip Agomo, William Ogala, Chimere Agomo, Onikepe A Folarin, Grace O Gbotosho, Christian T Happi

Journal:

 

Artemisinin-based combination treatments (ACTs) are the first-line treatments of uncomplicated Plasmodium falciparum malaria in many endemic areas but there are few evaluation of their efficacy in anaemic malarious children.

Last Updated: 8 Feb 2017

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Hidden reservoir of resistant parasites: the missing link in the elimination of falciparum malaria.
 

Author(s): Rashad Abdul-Ghani, Mohammed A K Mahdy, John C Beier, Leonardo K Basco

Journal:

 

To successfully eliminate malaria, an integrated system that includes a number of approaches and interventions-aimed at overcoming the threat of antimalarial drug resistance-is required. Significant progress has been made in reducing malaria incidence through large-scale use of artemisinin-based ...

Last Updated: 7 Feb 2017

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A Two-Dimensional Numerical Investigation of Transport of Malaria-Infected Red Blood Cells in Stenotic Microchannels.
 

Author(s): Tong Wang, Yong Tao, Uwitije Rongin, Zhongwen Xing

Journal: Biomed Res Int. 2016 ;2016():1801403.

 

The malaria-infected red blood cells experience a significant decrease in cell deformability and increase in cell membrane adhesion. Blood hemodynamics in microvessels is significantly affected by the alteration of the mechanical property as well as the aggregation of parasitized ...

Last Updated: 20 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malaria" returned 988 free, full-text review articles on human participants. First 3 results:

Lessons learnt from 20 years surveillance of malaria drug resistance prior to the policy change in Burkina Faso.
 

Author(s): Halidou Tinto, Innocent Valea, Jean-Bosco Ouédraogo, Tinga Robert Guiguemdé

Journal: Ann Parasitol. 2016 ;62(1):17-24.

 

The history of drug resistance to the previous antimalarial drugs, and the potential for resistance to evolve to Artemisinin-based combination therapies, demonstrates the necessity to set-up a good surveillance system in order to provide early warning of the development of resistance. ...

Last Updated: 6 Jun 2016

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Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data.
 

Author(s):

Journal:

 

Gametocytes are responsible for transmission of malaria from human to mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte carriage, dependent upon host, parasite and pharmacodynamic factors. The gametocytocidal properties of antimalarial drugs are important ...

Last Updated: 25 May 2016

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The development of malaria parasites in the mosquito midgut.
 

Author(s): Sandra Bennink, Meike J Kiesow, Gabriele Pradel

Journal: Cell. Microbiol.. 2016 07;18(7):905-18.

 

The mosquito midgut stages of malaria parasites are crucial for establishing an infection in the insect vector and to thus ensure further spread of the pathogen. Parasite development in the midgut starts with the activation of the intraerythrocytic gametocytes immediately after take-up ...

Last Updated: 10 Jun 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Rosiglitazone Adjunctive Therapy for Severe Malaria in Children
 

Status: Recruiting

Condition Summary: Malaria

 

Last Updated: 7 Jul 2016

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Last Updated: 2 Feb 2017

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Providers' Compliance to Malaria Treatment
 

Status: Recruiting

Condition Summary: Malaria

 

Last Updated: 31 Jul 2015

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