Malaria

Common Name(s)

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malaria" returned 10057 free, full-text research articles on human participants. First 3 results:

Predicting local malaria exposure using a Lasso-based two-level cross validation algorithm.
 

Author(s): Bienvenue Kouwaye, Fabrice Rossi, Noël Fonton, André Garcia, Simplice Dossou-Gbété, Mahouton Norbert Hounkonnou, Gilles Cottrell

Journal:

 

Recent studies have highlighted the importance of local environmental factors to determine the fine-scale heterogeneity of malaria transmission and exposure to the vector. In this work, we compare a classical GLM model with backward selection with different versions of an automatic ...

Last Updated: 31 Oct 2017

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Identification of immune signatures predictive of clinical protection from malaria.
 

Author(s): John Joseph Valletta, Mario Recker

Journal:

 

Antibodies are thought to play an essential role in naturally acquired immunity to malaria. Prospective cohort studies have frequently shown how continuous exposure to the malaria parasite Plasmodium falciparum cause an accumulation of specific responses against various antigens that ...

Last Updated: 24 Oct 2017

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Cost-effectiveness of adding indoor residual spraying to case management in Afghan refugee settlements in Northwest Pakistan during a prolonged malaria epidemic.
 

Author(s): Natasha Howard, Lorna Guinness, Mark Rowland, Naeem Durrani, Kristian S Hansen

Journal:

 

Financing of malaria control for displaced populations is limited in scope and duration, making cost-effectiveness analyses relevant but difficult. This study analyses cost-effectiveness of adding prevention through targeted indoor residual spraying (IRS) to case management in Afghan ...

Last Updated: 23 Oct 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malaria" returned 1000 free, full-text review articles on human participants. First 3 results:

Surveillance in easy to access population subgroups as a tool for evaluating malaria control progress: A systematic review.
 

Author(s): Sanie S S Sesay, Emanuele Giorgi, Peter J Diggle, David Schellenberg, David G Lalloo, Dianne J Terlouw

Journal:

 

The need for surveillance systems generating targeted, data-driven, responsive control efforts to accelerate and sustain malaria transmission reduction has been emphasized by programme managers, policy makers and scientists. Surveillance using easy-to-access population subgroups (EAGs) ...

Last Updated: 16 Aug 2017

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Vaccine candidate discovery for the next generation of malaria vaccines.
 

Author(s): James Tuju, Gathoni Kamuyu, Linda M Murungi, Faith H A Osier

Journal: Immunology. 2017 Oct;152(2):195-206.

 

Although epidemiological observations, IgG passive transfer studies and experimental infections in humans all support the feasibility of developing highly effective malaria vaccines, the precise antigens that induce protective immunity remain uncertain. Here, we review the methodologies ...

Last Updated: 24 Jun 2017

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A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria.
 

Author(s): Gunanidhi Dhangadamajhi, Avishek Kar, Ronnaly Rout, Prabin Dhangadamajhi

Journal: Rev. Soc. Bras. Med. Trop.. ;50(2):153-160.

 

Toll-like receptors (TLRs) are critical mediators of the inflammatory response to malarial infection, and gene polymorphisms affecting TLR function may be partially responsible for inter-individual variation in disease manifestation. However, there are inconsistencies in the associations ...

Last Updated: 31 May 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Rosiglitazone Adjunctive Therapy for Severe Malaria in Children
 

Status: Recruiting

Condition Summary: Malaria

 

Last Updated: 7 Jul 2016

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Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria.
 

Status: Recruiting

Condition Summary: Malaria

 

Last Updated: 2 Nov 2017

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