Malignant pheochromocytoma

Common Name(s)

Malignant pheochromocytoma

Malignant pheochromocytoma as opposed to benign, is a form of pheochromocytoma that is cancerous. Pheochromocytoma is a rare, usually noncancerous (benign) tumor that develops in cells in the center of an adrenal gland. There are two adrenal glands in the human body, one on the top of each kidney. They are shaped like triangles, and each is about a ½ inch high and 3 inches long.

Headache, sweating, and a fast heartbeat are typical symptoms of pheochromocytoma, usually in association with markedly high blood pressure.

However, less than 10 percent of pheochromocytoma's surgically removed are found to be malignant. Treatment options for malignancy include surgery, radiation, and chemotherapy. Research in this field is rapidly progressing.

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Condition Specific Organizations

Following organizations serve the condition "Malignant pheochromocytoma" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malignant pheochromocytoma" returned 63 free, full-text research articles on human participants. First 3 results:

Successful treatment of malignant pheochromocytoma with sacrum metastases: A case report.
 

Author(s): Shuzhong Liu, Xi Zhou, An Song, William A Li, Radhika Rastogi, Yipeng Wang, Yong Liu

Journal: Medicine (Baltimore). 2018 Aug;97(35):e12184.

 

Malignant pheochromocytoma in the spine is a rare disease without standard curative managements so far. The objective of this article is to report a very rare case of malignant pheochromocytoma with sacrum metastases causing severe lumbosacral pain, which was presented with acute ...

Last Updated: 31 Dec 1969

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Giant malignant pheochromocytoma in an elderly patient: A case report.
 

Author(s): Chengquan Ma, Erlin Sun, Bingxin Lu

Journal: Medicine (Baltimore). 2018 May;97(19):e0614.

 

Malignant pheochromocytoma is a rare disease and surgical resection is the only curative treatment.

Last Updated: 31 Dec 1969

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Malignant Pheochromocytoma and Paraganglioma: 272 Patients Over 55 Years.
 

Author(s): Oksana Hamidi, William F Young, Nicole M Iñiguez-Ariza, Nana Esi Kittah, Lucinda Gruber, Cristian Bancos, Shrikant Tamhane, Irina Bancos

Journal: J. Clin. Endocrinol. Metab.. 2017 09;102(9):3296-3305.

 

Malignant pheochromocytoma (PHEO) and paraganglioma (PGL) are rare and knowledge of the natural history is limited.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malignant pheochromocytoma" returned 9 free, full-text review articles on human participants. First 3 results:

What determines mortality in malignant pheochromocytoma? - Report of a case with eighteen-year survival and review of the literature.
 

Author(s): Matheus de Oliveira Andrade, Vinícius Santos da Cunha, Dayana Carla de Oliveira, Olívia Laquis de Moraes, Adriana Lofrano-Porto

Journal: Arch Endocrinol Metab. ;62(2):264-269.

 

Pheochromocytoma (PCC) is a tumor derived from adrenomedullary chromaffin cells. Prognosis of malignant PCC is generally poor due to local recurrence or metastasis. We aim to report a case of malignant PCC with 18-year survival and discuss which factors may be related to mortality ...

Last Updated: 31 Dec 1969

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Malignant pheochromocytoma with multiple vertebral metastases causing acute incomplete paralysis during pregnancy: Literature review with one case report.
 

Author(s): Shuzhong Liu, An Song, Xi Zhou, Xiangyi Kong, William A Li, Yipeng Wang, Yong Liu

Journal: Medicine (Baltimore). 2017 Nov;96(44):e8535.

 

We present a rare case of malignant pheochromocytoma with thoracic metastases during pregnancy that presented with symptoms of myelopathy and was treated with circumferential decompression, stabilization, and radiation. The management of this unique case is not well documented. The ...

Last Updated: 31 Dec 1969

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Composite pheochromocytoma with a malignant peripheral nerve sheath tumor: Case report and review of the literature.
 

Author(s): Takeshi Namekawa, Takanobu Utsumi, Takashi Imamoto, Koji Kawamura, Takashi Oide, Tomoaki Tanaka, Naoki Nihei, Hiroyoshi Suzuki, Yukio Nakatani, Tomohiko Ichikawa

Journal: Asian J Surg. 2016 Jul;39(3):187-90.

 

Adrenal tumors with more than one cellular component are uncommon. Furthermore, an adrenal tumor composed of a pheochromocytoma and a malignant peripheral nerve sheath tumor is extremely rare. A composite pheochromocytoma with malignant peripheral nerve sheath tumor in a 42-year-old ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Compassionate Use of 131I-MIBG for Patients With Malignant Pheochromocytoma
 

Status: Available

Condition Summary: Pheochromocytoma; Paraganglioma

 

Last Updated: 11 Dec 2017

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Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Malignant Adrenal Gland Pheochromocytoma; Malignant Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma

 

Last Updated: 13 Mar 2018

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