Malignant tumor of testis

Common Name(s)

Malignant tumor of testis

Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by {43:Rapley et al., 2000}). Genetic Heterogeneity of Testicular Germ Cell Tumors A locus for testicular germ cell tumors (TGCT1; {300228}) has been identified on chromosome Xq27.
 

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Condition Specific Organizations

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Scientific Literature

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Research articles describe the outcome of a single study. They are the published results of original research.
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The terms "Malignant tumor of testis" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS
 

Status: Recruiting

Condition Summary: Testicular Neoplasms

 

Last Updated: 18 Jul 2017

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Last Updated: 9 Nov 2017

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Cause of Familial Testicular Cancer
 

Status: Recruiting

Condition Summary: Testicular Cancer

 

Last Updated: 18 Oct 2017

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