Marburg hemorrhagic fever

Common Name(s)

Marburg hemorrhagic fever

Marburg hemorrhagic fever, also called Marbug virus disease (MVD), is a severe, possibly fatal disease caused by the Marburg virus. Outbreaks of MVD are more prevalent in African countries. MVD initially causes severe headache and a general feeilng of discomfort. Many people with Marburg hemorrhagic fever also develop severe bleeding, which sometimes leads to death. The virus is transmitted through direct contact with infected bodily fluids and tissues, as well as through handling of ill or dead infected wild animals. There is no cure currently available. Doctors usually treat individual symptoms to keep patients comfortable while their own immune system fights the invasive virus.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Marburg hemorrhagic fever" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Marburg hemorrhagic fever" returned 14 free, full-text research articles on human participants. First 3 results:

Interferon-β therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever.
 

Author(s): Lauren M Smith, Lisa E Hensley, Thomas W Geisbert, Joshua Johnson, Andrea Stossel, Anna Honko, Judy Y Yen, Joan Geisbert, Jason Paragas, Elizabeth Fritz, Gene Olinger, Howard A Young, Kathleen H Rubins, Christopher L Karp

Journal: J. Infect. Dis.. 2013 Jul;208(2):310-8.

 

There is a clear need for novel, effective therapeutic approaches to hemorrhagic fever due to filoviruses. Ebola virus hemorrhagic fever is associated with robust interferon (IFN)-α production, with plasma concentrations of IFN-α that greatly (60- to 100-fold) exceed those seen ...

Last Updated: 19 Jun 2013

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Transmission potential and design of adequate control measures for Marburg hemorrhagic fever.
 

Author(s): Marco Ajelli, Stefano Merler

Journal: PLoS ONE. 2012 ;7(12):e50948.

 

Marburg hemorrhagic fever is rare yet among the most severe diseases affecting humans, with case fatality ratio even higher than 80%. By analyzing the largest documented Marburg hemorrhagic fever epidemic, which occurred in Angola in 2005 and caused 329 deaths, and data on viral load ...

Last Updated: 19 Dec 2012

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Retrospective evaluation of control measures for contacts of patient with Marburg hemorrhagic fever.
 

Author(s): Aura Timen, Leslie D Isken, Patricia Willemse, Franchette van den Berkmortel, Marion P G Koopmans, Danielle E C van Oudheusden, Chantal P Bleeker-Rovers, Annemarie E Brouwer, Richard P T M Grol, Marlies E J L Hulscher, Jaap T van Dissel

Journal: Emerging Infect. Dis.. 2012 Jul;18(7):1107-14.

 

After an imported case of Marburg hemorrhagic fever was reported in 2008 in the Netherlands, control measures to prevent transmission were implemented. To evaluate consequences of these measures, we administered a structured questionnaire to 130 contacts classified as either having ...

Last Updated: 19 Jun 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Marburg hemorrhagic fever" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MVA-BN®-Filo and Ad26.ZEBOV Vaccines in Healthy Volunteers
 

Status: Not yet recruiting

Condition Summary: Ebola Disease; Marburg Disease

 

Last Updated: 26 Jan 2017

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