Measles

Common Name(s)

Measles

Measles is a serious, highly contagious disease caused by a virus in the paramyxovirus family. Despite there being a measles vaccination, measles continues to remain one of the leading causes of death among young children globally. More than 95% of the cases of measles occur in developing or low-income countries that have poor health infrastructures, particularly in parts of Africa and Asia. The virus normally grows in the cells that line the back of the throat and lungs. Measles is transmitted through coughing and sneezing, close personal contact, or direct contact with infected persons. Symptoms include a high fever beginning about 10 to 12 days after initial exposure, runny nose, cough, watery eyes, and small white spots inside the cheeks. A rash breaks out several days later, typically on the face and upper neck, then spreads to the hands and feet. Serious complications of measles include blindness, inflammation of the brain, severe diarrhea, dehydration, ear infections, severe respiratory infections, and death.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Measles" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Measles" returned 2627 free, full-text research articles on human participants. First 3 results:

Progress Toward Measles Elimination - Western Pacific Region, 2013-2017.
 

Author(s): José E Hagan, Jennifer L Kriss, Yoshihiro Takashima, Kayla Mae L Mariano, Roberta Pastore, Varja Grabovac, Alya J Dabbagh, James L Goodson

Journal:

 

In 2005, the Regional Committee for the World Health Organization (WHO) Western Pacific Region (WPR)* established a goal for measles elimination by 2012 (1). To achieve this goal, the 37 WPR countries and areas implemented the recommended strategies in the WPR Plan of Action for Measles ...

Last Updated: 31 Dec 1969

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Occurrence of measles in a country with elimination status: Amplifying measles infection in hospitalized children due to imported virus.
 

Author(s): HyeEun Eom, YoungJoon Park, JooWhee Kim, Jeong-Sun Yang, HaeJi Kang, Kisoon Kim, Byung Chul Chun, Ok Park, Jeong Ik Hong

Journal:

 

The Republic of Korea declared measles elimination in 2006. However, a measles outbreak occurred in 2013. This study aimed to identify the epidemiological characteristics of the sources of infection and the pattern of measles transmission in 2013 in South Korea. We utilized surveillance ...

Last Updated: 31 Dec 1969

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Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells.
 

Author(s): Brigitta M Laksono, Christina Grosserichter-Wagener, Rory D de Vries, Simone A G Langeveld, Maarten D Brem, Jacques J M van Dongen, Peter D Katsikis, Marion P G Koopmans, Menno C van Zelm, Rik L de Swart

Journal:

 

Measles is characterized by a transient immune suppression, leading to an increased risk of opportunistic infections. Measles virus (MV) infection of immune cells is mediated by the cellular receptor CD150, expressed by subsets of lymphocytes, dendritic cells, macrophages, and thymocytes. ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Measles" returned 117 free, full-text review articles on human participants. First 3 results:

A New Combined Vaccine Against Measles, Mumps, Rubella and Varicella in India.
 

Author(s): Nitin Shah, Raunak Parikh, Giacomo Casabona, Shafi Kolhapure

Journal: Indian Pediatr. 2017 12;54(12):1041-1046.

 

A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children ...

Last Updated: 31 Dec 1969

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A review of measles control in Kenya, with focus on recent innovations.
 

Author(s): Kasidet Manakongtreecheep, Robert Davis

Journal:

 

Despite the existence of a highly effective measles vaccine and the decrease in worldwide deaths from measles by more than 79% from the 2000 baseline levels, measles today remains one of the leading causes of vaccine-preventable deaths in the world. The African region is a key player ...

Last Updated: 31 Dec 1969

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Available studies fail to provide strong evidence of increased risk of diarrhea mortality due to measles in the period 4-26 weeks after measles rash onset.
 

Author(s): Bianca D Jackson, Robert E Black

Journal:

 

Measles vaccination effectiveness studies showed dramatic decreases in all-cause mortality in excess of what would be expected from the prevention of measles disease alone. This invited speculation that measles infection may increase the risk of diarrhea morbidity and mortality subsequent ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Induction of Immunity Against Measles in Pediatric Liver Transplant Recipients
 

Status: Recruiting

Condition Summary: Measles

 

Last Updated: 29 Dec 2016

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Last Updated: 9 May 2017

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Measles-Rubella Vaccine Immunogenicity at 6 and 9 Months of Age
 

Status: Not yet recruiting

Condition Summary: Measles; Rubella; Rubella Syndrome, Congenital

 

Last Updated: 1 Mar 2017

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