Meningioma, familial

Common Name(s)

Meningioma, familial

Meningiomas are, in general, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord. Meningiomas are believed to be the most common primary tumors of the central nervous system in man. The vast majority of meningiomas are sporadic; familial occurrence of meningioma is rare ({58:Zang, 2001}). Familial or multiple meningiomas may also be seen in tumor predisposition syndromes. Some patients with schwannomatosis ({162091}), caused by mutation in the SMARCB1 gene, may develop meningiomas. One patient with malignant gliomas (GLM2; {613028}) associated with a mutation in the PTEN gene ({601728}) developed a meningioma ({51:Staal et al., 2002}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Meningioma, familial" for support, advocacy or research.

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Scientific Literature

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Research articles describe the outcome of a single study. They are the published results of original research.
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of Afatinib for Brain Cancer
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 19 Oct 2017

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