Metaplastic carcinoma of the breast

Common Name(s)

Metaplastic carcinoma of the breast

Metaplastic carcinoma of the breast is a rare type of cancer that usually develops in one type of cell and changes to another type of cell with a different function. This cancer forms when a change (mutation) in DNA causes certain cells to grow out of control, forming a lump or a tumor. The most common location where metaplastic carcinoma of the breast develops is in the outer layer of cells forming the breast glands. Some of these cancerous cells can break off and spread (metastasize) to other parts of the body and grow there. The cancer commonly spreads to the lymph nodes, most frequently in the neck and head region. Some types of metaplastic carcinoma of the breast may also spread to the lungs.

Common symptoms include skin irritation or tenderness in the breast area, change in breast size, and formation of a persistent sore. There may also be swelling or finding of a lump in the breast or under the arm, which may or may not be painful. Depending on the size of the cancer, one may experience pain and rash formation in the breast as well. Diagnoses are made usually with a combination of a physical exam, imaging studies, and other laboratory studies.

This condition most commonly occurs in females between the ages of 50 and 60, though it can appear in all age groups. Risk factors that increase one’s risk for developing the condition include a family history of breast cancer or inheriting a change (mutation) in a BRCA1 or BRCA2 gene.

Treatment options depend on many factors such as how large the cancer is and if it has spread to other areas of the body. If you or a family member has been diagnosed with metaplastic carcinoma of the breast, talk to your doctor about the most current treatment options. Support groups are also available for more resources and information. Meeting with a genetic counselor may also be helpful to better understand cancer risks and to discuss genetic testing options.

Source: Advocacy organizations associated with the condition.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Metaplastic carcinoma of the breast" for support, advocacy or research.

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Scientific Literature

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Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Metaplastic carcinoma of the breast" returned 0 free, full-text research articles on human participants.

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The terms "Metaplastic carcinoma of the breast" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
 

Status: Recruiting

Condition Summary: Acinar Cell Carcinoma; Adenoid Cystic Carcinoma; Adrenal Cortex Carcinoma; Adrenal Gland Pheochromocytoma; Anal Canal Neuroendocrine Carcinoma; Anal Canal Undifferentiated Carcinoma; Appendix Mucinous Adenocarcinoma; Bartholin Gland Transitional Cell Carcinoma; Bladder Adenocarcinoma; Cervical Adenocarcinoma; Cholangiocarcinoma; Chordoma; Colorectal Squamous Cell Carcinoma; Desmoid-Type Fibromatosis; Endometrial Transitional Cell Carcinoma; Endometrioid Adenocarcinoma; Esophageal Neuroendocrine Carcinoma; Esophageal Undifferentiated Carcinoma; Extrahepatic Bile Duct Carcinoma; Fallopian Tube Adenocarcinoma; Fallopian Tube Transitional Cell Carcinoma; Fibromyxoid Tumor; Gastric Neuroendocrine Carcinoma; Gastric Squamous Cell Carcinoma; Gastrointestinal Stromal Tumor; Giant Cell Carcinoma; Intestinal Neuroendocrine Carcinoma; Intrahepatic Cholangiocarcinoma; Lung Carcinoid Tumor; Lung Sarcomatoid Carcinoma; Major Salivary Gland Carcinoma; Malignant Odontogenic Neoplasm; Malignant Peripheral Nerve Sheath Tumor; Malignant Testicular Sex Cord-Stromal Tumor; Metaplastic Breast Carcinoma; Metastatic Malignant Neoplasm of Unknown Primary Origin; Minimally Invasive Lung Adenocarcinoma; Mixed Mesodermal (Mullerian) Tumor; Mucinous Adenocarcinoma; Mucinous Cystadenocarcinoma; Nasal Cavity Adenocarcinoma; Nasal Cavity Carcinoma; Nasopharyngeal Carcinoma; Nasopharyngeal Papillary Adenocarcinoma; Nasopharyngeal Undifferentiated Carcinoma; Oral Cavity Carcinoma; Oropharyngeal Undifferentiated Carcinoma; Ovarian Adenocarcinoma; Ovarian Germ Cell Tumor; Ovarian Mucinous Adenocarcinoma; Ovarian Squamous Cell Carcinoma; Ovarian Transitional Cell Carcinoma; Pancreatic Acinar Cell Carcinoma; Pancreatic Neuroendocrine Carcinoma; Paraganglioma; Paranasal Sinus Adenocarcinoma; Paranasal Sinus Carcinoma; Parathyroid Gland Carcinoma; Pituitary Gland Carcinoma; Placental Choriocarcinoma; Placental-Site Gestational Trophoblastic Tumor; Primary Peritoneal High Grade Serous Adenocarcinoma; Pseudomyxoma Peritonei; Rare Disorder; Scrotal Squamous Cell Carcinoma; Seminal Vesicle Adenocarcinoma; Seminoma; Serous Cystadenocarcinoma; Small Intestinal Adenocarcinoma; Small Intestinal Squamous Cell Carcinoma; Spindle Cell Neoplasm; Squamous Cell Carcinoma of the Penis; Teratoma With Malignant Transformation; Testicular Non-Seminomatous Germ Cell Tumor; Thyroid Gland Carcinoma; Tracheal Carcinoma; Transitional Cell Carcinoma; Undifferentiated Gastric Carcinoma; Ureter Adenocarcinoma; Ureter Squamous Cell Carcinoma; Urethral Adenocarcinoma; Urethral Squamous Cell Carcinoma; Vaginal Adenocarcinoma; Vaginal Squamous Cell Carcinoma, Not Otherwise Specified; Vulvar Carcinoma

 

Last Updated: 14 Jun 2018

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