Moyamoya disease 2

Common Name(s)

Moyamoya disease 2

Moyamoya disease is a progressive cerebral angiopathy characterized by bilateral internal carotid artery stenosis and abnormal collateral vessels. The abnormal vessels resemble a 'puff of smoke' (moyamoya) on cerebral angiogram. Affected individuals can develop transient ischemic attacks and/or cerebral infarction, and rupture of the collateral vessels can cause intracranial hemorrhage (summary by {1:Kamada et al., 2011}). For a general phenotypic description and a discussion of genetic heterogeneity of moyamoya disease, see MYMY1 ({252350}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Moyamoya disease 2" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Moyamoya disease 2" returned 5 free, full-text research articles on human participants. First 3 results:

Deregulation of Retinaldehyde Dehydrogenase 2 Leads to Defective Angiogenic Function of Endothelial Colony-Forming Cells in Pediatric Moyamoya Disease.
 

Author(s): Ji Yeoun Lee, Youn Joo Moon, Hae-Ock Lee, Ae-Kyung Park, Seung-Ah Choi, Kyu-Chang Wang, Jung Woo Han, Je-Gun Joung, Hyun Seung Kang, Jeong Eun Kim, Ji Hoon Phi, Woong-Yang Park, Seung-Ki Kim

Journal: Arterioscler. Thromb. Vasc. Biol.. 2015 Jul;35(7):1670-7.

 

Moyamoya disease (MMD) is a common cause of childhood stroke, in which the abnormal function of the endothelial colony-forming cell (ECFC) plays a key role in the pathogenesis of the disease. This study was designed to identify genes involved in MMD pathogenesis using gene expression ...

Last Updated: 25 Jun 2015

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The GC + CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease.
 

Author(s): Young Seok Park, Young Joo Jeon, Hyun Seok Kim, In Bo Han, Seung-Hun Oh, Dong-Seok Kim, Nam Keun Kim

Journal:

 

To investigate the association of single-nucleotide polymorphisms (SNPs) in matrix metalloproteinases (MMPs)-2, -3, and -9 and tissue inhibitor of metalloproteinase (TIMP)-2 with moyamoya disease (MMD). We conducted a case-control study of MMD patients by assessing the prevalence ...

Last Updated: 15 Oct 2014

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Quantitative cerebral perfusion imaging in children and young adults with Moyamoya disease: comparison of arterial spin-labeling-MRI and H(2)[(15)O]-PET.
 

Author(s): R Goetti, G Warnock, F P Kuhn, R Guggenberger, R O'Gorman, A Buck, N Khan, I Scheer

Journal: AJNR Am J Neuroradiol. 2014 May;35(5):1022-8.

 

Cerebral perfusion assessment is important in the preoperative evaluation and postoperative follow-up of patients with Moyamoya disease. The objective of this study was to evaluate the correlation of quantitative CBF measurements performed with arterial spin-labeling-MR imaging and ...

Last Updated: 16 May 2014

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Reviews from the PubMed Database

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The terms "Moyamoya disease 2" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease
 

Status: Recruiting

Condition Summary: Moyamoya Disease

 

Last Updated: 2 Dec 2016

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Neurocognitive and Radiological Assessments in Adult Moyamoya Undergoing Surgery
 

Status: Recruiting

Condition Summary: Moyamoya Disease

 

Last Updated: 21 Aug 2017

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Moyamoya Disease Biomarkers in Patients With Intracranial Atherosclerotic Stroke
 

Status: Recruiting

Condition Summary: Moyamoya Disease; Intracranial Atherosclerotic Stroke; Intracranial Steno-occlusive Disease

 

Last Updated: 24 Apr 2017

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