Myd88 deficiency

Common Name(s)

Myd88 deficiency

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myd88 deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myd88 deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myd88 deficiency" returned 4 free, full-text research articles on human participants. First 3 results:

The effects of MyD88 deficiency on exploratory activity, anxiety, motor coordination, and spatial learning in C57BL/6 and APPswe/PS1dE9 mice.
 

Author(s): Jeong-Eun Lim, Min Song, Jingji Jin, Jinghong Kou, Abhinandan Pattanayak, Robert Lalonde, Ken-Ichiro Fukuchi

Journal: Behav. Brain Res.. 2012 Feb;227(1):36-42.

 

Toll-like receptors (TLRs) are a family of pattern-recognition receptors in innate immunity and provide a first line defense against pathogens and tissue injuries. In addition to important roles in infection, inflammation, and immune diseases, recent studies show that TLR signaling ...

Last Updated: 19 Dec 2011

Go To URL
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.
 

Author(s): Capucine Picard, Horst von Bernuth, Pegah Ghandil, Maya Chrabieh, Ofer Levy, Peter D Arkwright, Douglas McDonald, Raif S Geha, Hidetoshi Takada, Jens C Krause, C Buddy Creech, Cheng-Lung Ku, Stephan Ehl, László Maródi, Saleh Al-Muhsen, Sami Al-Hajjar, Abdulaziz Al-Ghonaium, Noorbibi K Day-Good, Steven M Holland, John I Gallin, Helen Chapel, David P Speert, Carlos Rodriguez-Gallego, Elena Colino, Ben-Zion Garty, Chaim Roifman, Toshiro Hara, Hideto Yoshikawa, Shigeaki Nonoyama, Joseph Domachowske, Andrew C Issekutz, Mimi Tang, Joanne Smart, Simona Eva Zitnik, Cyrille Hoarau, Dinakantha S Kumararatne, Adrian J Thrasher, E Graham Davies, Claire Bethune, Nicolas Sirvent, Dominique de Ricaud, Yildiz Camcioglu, Júlia Vasconcelos, Margarida Guedes, Artur Bonito Vitor, Carlos Rodrigo, Francisco Almazán, Maria Méndez, Juan Ignacio Aróstegui, Laia Alsina, Claudia Fortuny, Janine Reichenbach, James W Verbsky, Xavier Bossuyt, Rainer Doffinger, Laurent Abel, Anne Puel, Jean-Laurent Casanova

Journal: Medicine (Baltimore). 2010 Nov;89(6):403-25.

 

Autosomal recessive interleukin-1 receptor-associated kinase (IRAK)-4 and myeloid differentiation factor (MyD)88 deficiencies impair Toll-like receptor (TLR)- and interleukin-1 receptor-mediated immunity. We documented the clinical features and outcome of 48 patients with IRAK-4 deficiency ...

Last Updated: 8 Nov 2010

Go To URL
Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice.
 

Author(s): Toru Hosoi, Shota Yokoyama, Suguru Matsuo, Shizuo Akira, Koichiro Ozawa

Journal:

 

Multiple lines of evidence suggest innate immune response pathways to be involved in the development of obesity-associated diabetes although the molecular mechanism underling the disease is unknown. Recent observations suggest that saturated fatty acids can act as a ligand for toll-like ...

Last Updated: 8 Sep 2010

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myd88 deficiency" returned 1 free, full-text review articles on human participants. First 3 results:

Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency.
 

Author(s): Capucine Picard, Jean-Laurent Casanova, Anne Puel

Journal: Clin. Microbiol. Rev.. 2011 Jul;24(3):490-7.

 

Autosomal recessive IRAK-4 and MyD88 deficiencies predispose affected patients to recurrent invasive pyogenic bacterial infection. Both defects result in the selective impairment of cellular responses to Toll-like receptors (TLRs) other than TLR3 and of cellular responses to most ...

Last Updated: 7 Jul 2011

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.