Myoclonic seizures

Common Name(s)

Myoclonic seizures

Myoclonic seizures are a specific type of seizure that cause sudden short jerk-like twitches in the muscles of the arms and legs. “Myo” means muscle and “clonus” means quickly switching to and from tensing and relaxing; so the word myoclonus means the quick tensing and relaxing of muscles. This type of seizure is very short, typically lasting only a second or two. In fact, many people who do not have seizures can have myoclonus that causes their body to suddenly jerk themselves awake after falling asleep. Myoclonic seizures often occur as a part of other epilepsy conditions, such as juvenile myoclonic epilepsy, Lennox-Gastaut syndrome, and progressive myoclonic epilepsy. When myoclonic seizures occur as part of an epilepsy condition, they tend to cause abnormal movements on both sides of the body at the same time. After a myoclonic seizure, a person is usually awake and can continue on with their normal activity. Epilepsy conditions that include myoclonic seizures usually begin in childhood but the seizures can occur at any age.

There are many causes of epilepsy conditions that include myoclonic seizures. These include genetic causes, head trauma, brain abnormalities, infectious diseases and injuries that occur before a baby is born (prenatal injury). Risk factors for epilepsy conditions include age (epilepsy conditions usually present in childhood or after the age of 60 years), previous head trauma and a family history of epilepsy conditions. To diagnose myoclonic seizures, doctors will typically take a detailed medical history and perform a test called electroencephalogram (EEG). EEGs test the brain for abnormal electrical activity associated with a seizure. Many people with myoclonic seizures can be treated with anti-epilepsy medications. Talk with your doctor to decide which treatment option is best for you or your child. Support groups are a good resource for support and additional information.

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Condition Specific Organizations

Following organizations serve the condition "Myoclonic seizures" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myoclonic seizures" returned 35 free, full-text research articles on human participants. First 3 results:

Myoclonic jerks are commonly associated with absence seizures in early-onset absence epilepsy.
 

Author(s): Hala Nasser, Elisa Lopez-Hernandez, Adina Ilea, Neli Le Morvan, Vanina Bellavoine, Catherine Delanoë, Stéphane Auvin

Journal: Epileptic Disord. 2017 Jun;19(2):137-146.

 

Typical absence seizures are observed in various epilepsy syndromes, however, few series have focused on early-onset absence epilepsy (EOAE). We aimed to evaluate the occurrence of this seizure type in children under 4 years of age in order to evaluate their electroclinical characteristics ...

Last Updated: 31 Dec 1969

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Epilepsy with myoclonic atonic seizures and chronic cerebellar symptoms associated with antibodies against glutamate receptors N2B and D2 in serum and cerebrospinal fluid.
 

Author(s): Ryuki Matsuura, Shin-Ichiro Hamano, Satoru Ikemoto, Yuko Hirata, Kotoko Suzuki, Kenjiro Kikuchi, Yukitoshi Takahashi

Journal: Epileptic Disord. 2017 Mar;19(1):94-98.

 

A 3-year-old boy with normal development presented with acute cerebellitis at one year and 10 months of age. His truncal ataxia resolved without treatment. He experienced a relapse of truncal ataxia and atonic seizures at 2 years and one month of age. Five months later, he experienced ...

Last Updated: 31 Dec 1969

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SLC6A1 Mutation and Ketogenic Diet in Epilepsy With Myoclonic-Atonic Seizures.
 

Author(s): Samantha Palmer, Meghan C Towne, Phillip L Pearl, Renee C Pelletier, Casie A Genetti, Jiahai Shi, Alan H Beggs, Pankaj B Agrawal, Catherine A Brownstein

Journal: Pediatr. Neurol.. 2016 Nov;64():77-79.

 

Epilepsy with myoclonic-atonic seizures, also known as myoclonic-astatic epilepsy or Doose syndrome, has been recently linked to variants in the SLC6A1 gene. Epilepsy with myoclonic-atonic seizures is often refractory to antiepileptic drugs, and the ketogenic diet is known for treating ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myoclonic seizures" returned 1 free, full-text review articles on human participants. First 3 results:

Treatment strategies for myoclonic seizures and epilepsy syndromes with myoclonic seizures.
 

Author(s): James W Wheless, Raman Sankar

Journal: Epilepsia. 2003 ;44 Suppl 11():27-37.

 

Despite the availability of numerous treatment options, the diagnosis and treatment of myoclonic seizures continue to be challenging. Based on clinical experience, valproate and benzodiazepines have historically been used to treat myoclonic seizures. However, many more treatment options ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Biology of Juvenile Myoclonic Epilepsy
 

Status: Recruiting

Condition Summary: Juvenile Myoclonic Epilepsy

 

Last Updated: 12 Jan 2018

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Genetic Characterization of Movement Disorders and Dementias
 

Status: Recruiting

Condition Summary: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis

 

Last Updated: 10 May 2018

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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
 

Status: Recruiting

Condition Summary: Mitochondrial Disorders; Mitochondrial Genetic Disorders; Mitochondrial Diseases; Disorder of Mitochondrial Respiratory Chain Complexes; Deletion and Duplication of Mitochondrial DNA

 

Last Updated: 21 Aug 2017

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