Myositis

Common Name(s)

Myositis

Myositis is an inflammation of muscles. Affected individuals will have difficulty contracting their muscles because of the damage to the muscle fibers from the inflammation. The inflammation may be caused by the body attacking its own tissues (autoimmune), infection, drug side effects, or injury. After traumatic injury, myositis can occur in bruised areas. The inflammation may also be idiopathic, or without a known cause.

Common symptoms include muscle soreness, weakness, difficulty swallowing, and trouble climbing stairs. Individuals affected by myositis may have a decrease in their muscle mass (atrophy) for long periods of time. Individuals affected by the flu or other viral infections often experience myositis during their recovery. This is frequently seen in young children and manifests as severe leg pain and inability to walk properly for a few days.

Doctors can use lab tests, a physical exam, medical imaging, and blood or muscle samples to diagnose myositis. Treatment will depend on the cause of the inflammation. Myositis without a known cause may persist for long periods of time, while inflammation caused by infection or drugs will go away after the infection is cleared or the drug has been stopped. Common treatments for myositis include medication, physical therapy, and dietary supplements. If you are suffering from myositis, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myositis" returned 475 free, full-text research articles on human participants. First 3 results:

Recovery from severe dysphagia in systemic sclerosis - myositis overlap: a case report.
 

Author(s): Keith J Chinniah, Girish M Mody

Journal: Afr Health Sci. 2017 Jun;17(2):593-596.

 

Dysphagia is common in inflammatory myopathies and usually responds to corticosteroids. Severe dysphagia requiring feeding by percutaneous endoscopic gastrostomy is associated with significant morbidity and high mortality.

Last Updated: 31 Dec 1969

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Concomitant occurrence of FXTAS and clinically defined sporadic inclusion body myositis: report of two cases.
 

Author(s): Mirna Lechpammer, Verónica Martínez Cerdeńo, Michael Ryan Hunsaker, Mina Hah, Hilary Gonzales, Steve Tisch, Ronald Joffe, Roger Pamphlett, Flora Tassone, Paul J Hagerman, Samuel J Bolitho, Randi J Hagerman

Journal: Croat. Med. J.. 2017 Aug;58(4):310-315.

 

This report describes unique presentations of inclusion body myositis (IBM) in two unrelated patients, one male and one female, with genetically and histologically confirmed fragile X-associated tremor/ataxia syndrome (FXTAS). We summarize overlapping symptoms between two disorders, ...

Last Updated: 31 Dec 1969

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The EuroMyositis registry: an international collaborative tool to facilitate myositis research.
 

Author(s): James B Lilleker, Jiri Vencovsky, Guochun Wang, Lucy R Wedderburn, Louise Pyndt Diederichsen, Jens Schmidt, Paula Oakley, Olivier Benveniste, Maria Giovanna Danieli, Katalin Danko, Nguyen Thi Phuong Thuy, Monica Vazquez-Del Mercado, Helena Andersson, Boel De Paepe, Jan L deBleecker, Britta Maurer, Liza J McCann, Nicolo Pipitone, Neil McHugh, Zoe E Betteridge, Paul New, Robert G Cooper, William E Ollier, Janine A Lamb, Niels Steen Krogh, Ingrid E Lundberg, Hector Chinoy,

Journal: Ann. Rheum. Dis.. 2018 Jan;77(1):30-39.

 

The EuroMyositis Registry facilitates collaboration across the idiopathic inflammatory myopathy (IIM) research community. This inaugural report examines pooled Registry data.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myositis" returned 66 free, full-text review articles on human participants. First 3 results:

Coexisting myasthenia gravis, myositis, and polyneuropathy induced by ipilimumab and nivolumab in a patient with non-small-cell lung cancer: A case report and literature review.
 

Author(s): Jia-Hung Chen, Kang-Yun Lee, Chaur-Jong Hu, Chen-Chih Chung

Journal: Medicine (Baltimore). 2017 Dec;96(50):e9262.

 

Immune checkpoint inhibitors have led to the development of new approaches for cancer treatment with positive outcomes. However, checkpoint blockade is associated with a unique spectrum of immune-related adverse events (irAEs), which may cause irreversible neurological deficits and even death.

Last Updated: 31 Dec 1969

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Haycocknema perplexum: an emerging cause of parasitic myositis in Australia.
 

Author(s): Luke J Vos, Thomas Robertson, Enzo Binotto

Journal:

 

Haycocknema perplexum is a rare cause of parasitic myositis, with all cases of human infection reported from Australia. This case involved an 80-year-old Queensland wildlife carer, who presented with muscle weakness, mild eosinophilia and creatine kinase elevation. This case supports ...

Last Updated: 31 Dec 1969

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[Myositis ossificans circumscripta, an unusual location: about a case and review of the literature].
 

Author(s): Ikram Taam, Khouloud Boussouni, Bouchaib Redouane, Touriya Amil, Rachida Saouab

Journal:

 

Myositis ossificans circumscripta (MOC) is a rare condition characterized by nontumoral heterotopic ossification of the soft tissues. This condition affects young subjects, occurring mainly after trauma. It is ubiquitous, predominantly located in girdles and limbs. We report the case ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Belimumab in Myositis
 

Status: Recruiting

Condition Summary: Myositis

 

Last Updated: 18 Aug 2017

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Molecular Profile of the Evolution of Inclusion Body Myositis
 

Status: Recruiting

Condition Summary: Inclusion Body Myositis

 

Last Updated: 12 Jan 2018

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Study of Arimoclomol in Inclusion Body Myositis (IBM)
 

Status: Recruiting

Condition Summary: Inclusion Body Myositis

 

Last Updated: 12 Feb 2018

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