Myositis

Common Name(s)

Myositis

Myositis is an inflammation of muscles. Affected individuals will have difficulty contracting their muscles because of the damage to the muscle fibers from the inflammation. The inflammation may be caused by the body attacking its own tissues (autoimmune), infection, drug side effects, or injury. After traumatic injury, myositis can occur in bruised areas. The inflammation may also be idiopathic, or without a known cause.

Common symptoms include muscle soreness, weakness, difficulty swallowing, and trouble climbing stairs. Individuals affected by myositis may have a decrease in their muscle mass (atrophy) for long periods of time. Individuals affected by the flu or other viral infections often experience myositis during their recovery. This is frequently seen in young children and manifests as severe leg pain and inability to walk properly for a few days.

Doctors can use lab tests, a physical exam, medical imaging, and blood or muscle samples to diagnose myositis. Treatment will depend on the cause of the inflammation. Myositis without a known cause may persist for long periods of time, while inflammation caused by infection or drugs will go away after the infection is cleared or the drug has been stopped. Common treatments for myositis include medication, physical therapy, and dietary supplements. If you are suffering from myositis, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

View Details

 

General Support Organizations

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General Resources

Myositis Basics (Inflammatory Myopathy)

The Idiopathic Inflammatory Myopathies (IIM) (we refer to as simply myositis) are rare, autoimmune diseases that affect muscle, skin, lungs and other organs.

Updated 3 Mar 2018

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myositis" returned 474 free, full-text research articles on human participants. First 3 results:

Alternating and Relapsing Migratory Orbital Myositis.
 

Author(s): Hee Jung Yang, Hee Jong Shin, Ji Sun Paik, Suk Woo Yang

Journal: Korean J Ophthalmol. 2017 12;31(6):568-569.

 

Last Updated: 31 Dec 1969

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Recovery from severe dysphagia in systemic sclerosis - myositis overlap: a case report.
 

Author(s): Keith J Chinniah, Girish M Mody

Journal: Afr Health Sci. 2017 Jun;17(2):593-596.

 

Dysphagia is common in inflammatory myopathies and usually responds to corticosteroids. Severe dysphagia requiring feeding by percutaneous endoscopic gastrostomy is associated with significant morbidity and high mortality.

Last Updated: 31 Dec 1969

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Concomitant occurrence of FXTAS and clinically defined sporadic inclusion body myositis: report of two cases.
 

Author(s): Mirna Lechpammer, Verónica Martínez Cerdeńo, Michael Ryan Hunsaker, Mina Hah, Hilary Gonzales, Steve Tisch, Ronald Joffe, Roger Pamphlett, Flora Tassone, Paul J Hagerman, Samuel J Bolitho, Randi J Hagerman

Journal: Croat. Med. J.. 2017 Aug;58(4):310-315.

 

This report describes unique presentations of inclusion body myositis (IBM) in two unrelated patients, one male and one female, with genetically and histologically confirmed fragile X-associated tremor/ataxia syndrome (FXTAS). We summarize overlapping symptoms between two disorders, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myositis" returned 76 free, full-text review articles on human participants. First 3 results:

Case report: A rare case of focal myositis presenting as Sartorius muscle contracture: A case report and review of literature.
 

Author(s): Jin Wang, Juyang Jiao, Guanglei Zhao, Jingsheng Shi, Jun Xia

Journal: Medicine (Baltimore). 2018 May;97(20):e10766.

 

Focal myositis (FM) is a very rare myopathy of unknown etiology characterized by focal enlargement within one single skeletal muscle. In particular, it occurs only involving the Sartorius muscle has never been reported.

Last Updated: 31 Dec 1969

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Coexisting myasthenia gravis, myositis, and polyneuropathy induced by ipilimumab and nivolumab in a patient with non-small-cell lung cancer: A case report and literature review.
 

Author(s): Jia-Hung Chen, Kang-Yun Lee, Chaur-Jong Hu, Chen-Chih Chung

Journal: Medicine (Baltimore). 2017 Dec;96(50):e9262.

 

Immune checkpoint inhibitors have led to the development of new approaches for cancer treatment with positive outcomes. However, checkpoint blockade is associated with a unique spectrum of immune-related adverse events (irAEs), which may cause irreversible neurological deficits and even death.

Last Updated: 31 Dec 1969

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Effective induction therapy for anti-SRP associated myositis in childhood: A small case series and review of the literature.
 

Author(s): E L Binns, E Moraitis, S Maillard, S Tansley, N McHugh, T S Jacques, L R Wedderburn, C Pilkington, S A Yasin, K Nistala,

Journal:

 

Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to respond to conventional first line therapies. We present three cases where ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Belimumab in Myositis
 

Status: Recruiting

Condition Summary: Myositis

 

Last Updated: 18 Aug 2017

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Molecular Profile of the Evolution of Inclusion Body Myositis
 

Status: Recruiting

Condition Summary: Inclusion Body Myositis

 

Last Updated: 12 Jan 2018

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Study of Arimoclomol in Inclusion Body Myositis (IBM)
 

Status: Recruiting

Condition Summary: Inclusion Body Myositis

 

Last Updated: 12 Feb 2018

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