Nasal polyps

Common Name(s)

Nasal polyps

Nasal polyps are sac-like growths in the nasal passages, which is the area of the nose that extends from the nostrils up into the nose. These growths are not cancerous or harmful, but they may lead to problems such as if they become enlarged or if they obstruct the nasal passage. Small polyps may cause no symptoms at all, while large polyps may block drainage and lead to infection. Anyone can have nasal polyps, but they are more common in men and in people over age 40. Children who have nasal polyps should be screened for cystic fibrosis, as nasal polyps are a common finding in this disease. Risk factors for nasal polyps are asthma, sinus infections, presence of a foreign object in the nose, and allergic rhinitis (runny nose caused by allergies).

Symptoms of nasal polyps include nasal congestion, a runny nose, snoring, pain in the upper teeth or face, sneezing, loss of smell (anosmia), reduced sense of smell (hyposmia), itching around the eyes, headache, or infections. Nasal polyps can be diagnosed with a nasal endoscope, which is a lighted tube that is used to look up the nose. Treatment can include medications, such as nasal sprays and allergy medications, or surgery. If you have nasal polyps, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasal polyps" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasal polyps" returned 154 free, full-text research articles on human participants. First 3 results:

A family-based genome-wide association study of chronic rhinosinusitis with nasal polyps implicates several genes in the disease pathogenesis.
 

Author(s): Anton Bohman, Julius Juodakis, Martin Oscarsson, Jonas Bacelis, Mats Bende, Åsa Torinsson Naluai

Journal:

 

The pathogenesis of chronic rhinosinusitis with nasal polyps is largely unknown. Previous studies have given valuable information about genetic variants associated with this disease but much is still unexplained. Our goal was to identify genetic markers and genes associated with susceptibility ...

Last Updated: 31 Dec 1969

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Interleukin-33 promotes the inflammatory reaction in chronic rhinosinusitis with nasal polyps by NF-κB signaling pathway.
 

Author(s): L Zhang, L-L Jiang, Z-W Cao

Journal: Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4501-4508.

 

Interleukin (IL)-33 promotes T helper (Th2) immune response and may be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). Using murine and human specimens, we evaluated the role of IL-33 in CRSwNP.

Last Updated: 31 Dec 1969

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Role of epigenetics in the pathogenesis of chronic rhinosinusitis with nasal polyps.
 

Author(s): Jong-Yeup Kim, Dong-Kyu Kim, Myeong Sang Yu, Min-Ji Cha, Seong-Lan Yu, Jaeku Kang

Journal: Mol Med Rep. 2018 Jan;17(1):1219-1227.

 

Chronic rhinosinusitis (CRS) is a highly prevalent disease characterized by mucosal inflammation of the nose and paranasal sinuses. CRS can be divided into two main categories, CRS with nasal polyps (NPs; CRSwNP) and CRS without NPs (CRSsNP). Although the pathophysiology of CRS remains ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasal polyps" returned 12 free, full-text review articles on human participants. First 3 results:

Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review.
 

Author(s): Vanessa Ramos Pires Dinarte, Anemari Ramos Dinarte Dos Santos, Luiza Ferreira de Araújo, Mariah Guieiro Alves Dos Reis, Edwin Tamashiro, Fabiana Cardoso Pereira Valera, Wilson Araújo da Silva Júnior, Wilma Terezinha Anselmo-Lima

Journal: Braz J Otorhinolaryngol. ;83(6):705-711.

 

Chronic rhinosinusitis with nasal polyps is a multifactorial disease with a complex pathophysiology involving multiple genetic and environmental factors.

Last Updated: 31 Dec 1969

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Chronic Rhinosinusitis without Nasal Polyps.
 

Author(s): Seong Ho Cho, Dae Woo Kim, Philippe Gevaert

Journal: J Allergy Clin Immunol Pract. ;4(4):575-82.

 

Chronic rhinosinusitis without nasal polyps (CRSsNP) is more prevalent than chronic rhinosinusitis with nasal polyps (CRSwNP). Certain diseases predispose to whereas others are associated with CRSsNP. Predisposing diseases include allergic and nonallergic upper and lower airway diseases, ...

Last Updated: 31 Dec 1969

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Chronic Rhinosinusitis with Nasal Polyps.
 

Author(s): Whitney W Stevens, Robert P Schleimer, Robert C Kern

Journal: J Allergy Clin Immunol Pract. ;4(4):565-72.

 

Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed by the presence of both subjective and objective evidence of chronic sinonasal inflammation. Symptoms include anterior or posterior rhinorrhea, nasal congestion, hyposmia, and/or facial pressure ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Activation of Hippo Pathway in Nasal Polyps
 

Status: Recruiting

Condition Summary: Nasal Polyps

 

Last Updated: 15 May 2017

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Effect of Benralizumab in Patients With Severe Nasal Polyps
 

Status: Recruiting

Condition Summary: Nasal Polyps

 

Last Updated: 10 Aug 2018

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Efficacy & Safety of OPN-375 Adults With Bilateral Nasal Polyps Using Nasoendoscopic Video
 

Status: Recruiting

Condition Summary: Bilateral Nasal Polyposis

 

Last Updated: 17 Jul 2018

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