Neurofibroma

Common Name(s)

Neurofibroma

A neurofibroma is a non-cancerous (benign) tumor that develops from the cells and tissues that cover nerves. Some people who develop neurofibromas have a genetic condition known as neurofibromatosis (NF). There are different types of NF, but type 1 is the most common.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neurofibroma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neurofibroma" returned 177 free, full-text research articles on human participants. First 3 results:

Gene signature associated with benign neurofibroma transformation to malignant peripheral nerve sheath tumors.
 

Author(s): Marta Martínez, Carlos O S Sorzano, Alberto Pascual-Montano, Jose M Carazo

Journal:

 

Benign neurofibromas, the main phenotypic manifestations of the rare neurological disorder neurofibromatosis type 1, degenerate to malignant tumors associated to poor prognosis in about 10% of patients. Despite efforts in the field of (epi)genomics, the lack of prognostic biomarkers ...

Last Updated: 25 May 2017

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Immortalization of human normal and NF1 neurofibroma Schwann cells.
 

Author(s): Hua Li, Lung-Ji Chang, Debbie R Neubauer, David F Muir, Margaret R Wallace

Journal: Lab. Invest.. 2016 Oct;96(10):1105-15.

 

Neurofibromas, which are benign Schwann cell tumors, are the hallmark feature in the autosomal dominant condition neurofibromatosis 1 (NF1) and are associated with biallelic loss of NF1 gene function. There is a need for effective therapies for neurofibromas, particularly the larger, ...

Last Updated: 23 Sep 2016

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Initial Exploration on Temporal Branch of Facial Nerve Function Preservation in Plexiform Neurofibroma Resection.
 

Author(s): Xiaojie Hu, Melia Bogari, Andy Tan, Xiaoyan Gao, Yang Gao, Hui Chen, Wei Li, Yunbo Jin, Gang Ma, Xiaoxi Lin

Journal: J Craniofac Surg. 2016 Sep;27(6):1589-92.

 

Large temporal plexiform neurofibroma (PNF) is an irritating problem that causes facial disfigurement. Surgical resection of PNF is the only effective way to remove the tumor as well as to improve the patient's facial appearance. However, temporal branch of the facial nerve (TBFN) ...

Last Updated: 8 Sep 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neurofibroma" returned 20 free, full-text review articles on human participants. First 3 results:

Giant vulval neurofibroma: A rare entity with review of literature.
 

Author(s): Lalita Negi, Shailja Puri Wahal, Anchana Gulati, Vijay Kaushal

Journal: J Cancer Res Ther. ;11(4):1045.

 

Last Updated: 17 Feb 2016

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A rare case study of a retropharyngeal neurofibroma and a brief literature review.
 

Author(s): I Atallah, J Gervasoni, E Gay, C A Righini

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2016 Feb;133(1):47-50.

 

Space occupying lesions in the retropharyngeal space are rare.

Last Updated: 15 Feb 2016

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Pediatric laryngeal neurofibroma: case report and review of the literature.
 

Author(s): Steven B Chinn, Ryan M Collar, John B McHugh, Norman D Hogikyan, Marc C Thorne

Journal: Int. J. Pediatr. Otorhinolaryngol.. 2014 Jan;78(1):142-7.

 

Presentation of a case of pediatric laryngeal neurofibroma (LNF) and review of the world literature. Comprehensive review of the world literature using Pubmed and Google scholar. Pediatric LNF was identified in 62 cases reported in the world literature. The most common presenting ...

Last Updated: 16 Dec 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas
 

Status: Recruiting

Condition Summary: Plexiform Neurofibromas

 

Last Updated: 5 May 2017

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Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas
 

Status: Not yet recruiting

Condition Summary: Neurofibromatosis Type 1; Plexiform Neurofibroma

 

Last Updated: 17 Oct 2017

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Photodynamic Therapy for Benign Dermal Neurofibromas
 

Status: Recruiting

Condition Summary: NEUROFIBROMATOSIS 1

 

Last Updated: 10 Aug 2017

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