Neuromyelitis optica spectrum disorder

Common Name(s)

Neuromyelitis optica spectrum disorder

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuromyelitis optica spectrum disorder" for support, advocacy or research.

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The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

Last Updated: 19 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuromyelitis optica spectrum disorder" for support, advocacy or research.

Logo
The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

http://www.guthyjacksonfoundation.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neuromyelitis optica spectrum disorder" returned 45 free, full-text research articles on human participants. First 3 results:

A prospective case-control study comparing optical coherence tomography characteristics in neuromyelitis optica spectrum disorder- optic neuritis and idiopathic optic neuritis.
 

Author(s): Xiujuan Zhao, Wei Qiu, Yuxin Zhang, Yan Luo, Xiulan Zhang, Lin Lu, Hui Yang

Journal:

 

Neuromyelitis optica spectrum disorder-optic neuritis (NMOSD-ON) can now be distinguished from other types of ON as a specific disease by the Aquaporin-4 antibody (AQP4-Ab) test. NMOSD-ON can cause severe retinal nerve fiber layer (RNFL) damage. The optical coherence tomography (OCT) ...

Last Updated: 31 Dec 1969

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A case report of neuromyelitis optica spectrum disorder with peripheral neuropathy as the first episode.
 

Author(s): Lu-Mei Chi, Yu Gao, Guang-Xian Nan

Journal: Medicine (Baltimore). 2018 Mar;97(10):e0059.

 

Neuromyelitis optica spectrum disorders (NMOSDs) represent recurrent autoimmune diseases, generally beginning with optic nerve neuritis or acute transverse myelitis.

Last Updated: 31 Dec 1969

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Environmental risk factors in neuromyelitis optica spectrum disorder: a case-control study.
 

Author(s): Sharareh Eskandarieh, Saharnaz Nedjat, Ibrahim Abdollahpour, Amir Reza Azimi, Abdorreza Naser Moghadasi, Nasrin Asgari, Mohammad Ali Sahraian

Journal: Acta Neurol Belg. 2018 Jun;118(2):277-287.

 

Neuromyelitis optica spectrum disorder (NMOSD) has unknown risk factors. The aim of this study was to identify the environmental risk factors for NMOSD. A case-control study was conducted in Tehran from 2015 to 2016 among 100 patients with NMOSD. Sex-matched healthy controls (n = 400) ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neuromyelitis optica spectrum disorder" returned 4 free, full-text review articles on human participants. First 3 results:

Optical Coherence Tomography and Magnetic Resonance Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder.
 

Author(s): Praveena Manogaran, James V M Hanson, Elisabeth D Olbert, Christine Egger, Carla Wicki, Christina Gerth-Kahlert, Klara Landau, Sven Schippling

Journal:

 

Irreversible disability in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) is largely attributed to neuronal and axonal degeneration, which, along with inflammation, is one of the major pathological hallmarks of these diseases. Optical coherence tomography ...

Last Updated: 31 Dec 1969

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Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.
 

Author(s): Stephane Kremer, Felix Renard, Sophie Achard, Marco A Lana-Peixoto, Jacqueline Palace, Nasrin Asgari, Eric C Klawiter, Silvia N Tenembaum, Brenda Banwell, Benjamin M Greenberg, Jeffrey L Bennett, Michael Levy, Pablo Villoslada, Albert Saiz, Kazuo Fujihara, Koon Ho Chan, Sven Schippling, Friedemann Paul, Ho Jin Kim, Jerome de Seze, Jens T Wuerfel, , Philippe Cabre, Romain Marignier, Thomas Tedder, Danielle van Pelt, Simon Broadley, Tanuja Chitnis, Dean Wingerchuk, Lekha Pandit, Maria Isabel Leite, Metha Apiwattanakul, Ingo Kleiter, Naraporn Prayoonwiwat, May Han, Kerstin Hellwig, Katja van Herle, Gareth John, D Craig Hooper, Ichiro Nakashima, Douglas Sato, Michael R Yeaman, Emmanuelle Waubant, Scott Zamvil, Olaf Stüve, Orhan Aktas, Terry J Smith, Anu Jacob, Kevin O'Connor

Journal: JAMA Neurol. 2015 Jul;72(7):815-22.

 

Brain parenchymal lesions are frequently observed on conventional magnetic resonance imaging (MRI) scans of patients with neuromyelitis optica (NMO) spectrum disorder, but the specific morphological and temporal patterns distinguishing them unequivocally from lesions caused by other ...

Last Updated: 31 Dec 1969

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MRI characteristics of neuromyelitis optica spectrum disorder: an international update.
 

Author(s): Ho Jin Kim, Friedemann Paul, Marco A Lana-Peixoto, Silvia Tenembaum, Nasrin Asgari, Jacqueline Palace, Eric C Klawiter, Douglas K Sato, Jérôme de Seze, Jens Wuerfel, Brenda L Banwell, Pablo Villoslada, Albert Saiz, Kazuo Fujihara, Su-Hyun Kim,

Journal: Neurology. 2015 Mar;84(11):1165-73.

 

Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to involve only the optic nerves and spinal cord. However, the discovery of highly specific anti-aquaporin-4 antibody diagnostic biomarker for NMO enabled recognition of more diverse clinical ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase III Study of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Neuromyelitis Optica Spectrum Disorders
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica Spectrum Disorders

 

Last Updated: 6 Nov 2017

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Treatment of Relapsed and/or Refractory AQP4-IgG Seropositive NMOSD by Tandem CAR T Cells Targeting CD19 and CD20
 

Status: Not yet recruiting

Condition Summary: Neuromyelitis Optica Spectrum Disorder

 

Last Updated: 21 Jul 2018

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Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
 

Status: Recruiting

Condition Summary: Multiple Sclerosis; Neuromyelitis Optica Spectrum Disorders

 

Last Updated: 7 Aug 2016

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