Neutropenia

Common Name(s)

Neutropenia

Neutropenia is a disorder in which individuals have an abnormally low count of neutrophils, a type of white blood cell that helps fight off infections. The low count can be caused by cancer, viral infections, autoimmune disorders or drugs that damage the function of bone marrow or neutrophil cells. The lower the neutrophil count, the more vulnerable an individual is to infection or sickness. Common symptoms of neutropenia include fevers and frequent infections, which can result in mouth ulcers, diarrhea, a burning sensation when urinating, unusual redness, pain, or a sore throat.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neutropenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neutropenia" returned 1005 free, full-text research articles on human participants. First 3 results:

Chemoradiotherapy completion and neutropenia risk in HIV patients with cervical cancer.
 

Author(s): Ines Vendrell, Arlindo R Ferreira, André N Abrunhosa-Branquinho, Patrícia Miguel Semedo, Catarina F Pulido, Marília Jorge, Maria Filomena de Pina, Conceição Pinto, Luís Costa

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11592.

 

Cervical cancer (CC) is one of the acquired immunodeficiency syndrome (AIDS) defining diseases and the human immunodeficiency virus (HIV) infection is thought to relate with increased acute toxicity of chemoradiotherapy (CRT).We investigated the effect of HIV status in the incidence ...

Last Updated: 31 Dec 1969

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[Microorganisms isolated from blood cultures in children with cancer and high-risk febrile neutropenia from five hospitals in Santiago, Chile, 2012-2015].
 

Author(s): M Eliana Maldonado, Mirta Acuña, Ana M Álvarez, Carmen L Avilés, Verónica de la Maza, Carmen Salgado, Juan Tordecilla, Mónica Varas, Marcela Venegas, Milena Villarroel, Marcela Zubieta, M Elena Santolaya

Journal: Rev Chilena Infectol. 2018 04;35(2):140-146.

 

Microorganisms isolated from blood cultures (BC) in patients with febrile neutropenia (NF) vary over time, requiring systematic monitoring to guide appropriate empirical therapy.

Last Updated: 31 Dec 1969

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Integrative omics to detect bacteremia in patients with febrile neutropenia.
 

Author(s): Rachel S Kelly, Jessica Lasky-Su, Sai-Ching J Yeung, Richard M Stone, Jeffrey M Caterino, Sean C Hagan, Gary H Lyman, Lindsey R Baden, Brett E Glotzbecker, Christopher J Coyne, Christopher W Baugh, Daniel J Pallin

Journal:

 

Cancer chemotherapy-associated febrile neutropenia (FN) is a common condition that is deadly when bacteremia is present. Detection of bacteremia depends on culture, which takes days, and no accurate predictive tools applicable to the initial evaluation are available. We utilized metabolomics ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neutropenia" returned 99 free, full-text review articles on human participants. First 3 results:

[Febrile neutropenia in cancer patients: management in the emergency room].
 

Author(s): Daniel Rivera-Salgado, Kathia Valverde-Muñoz, María L Ávila-Agüero

Journal: Rev Chilena Infectol. ;35(1):62-71.

 

Febrile neutropenia is a life-threatening condition that requires immediate attention, especially in patients with chemotherapy-related neutropenia. Patients with febrile neutropenia have a much greater risk of developing bacterial disease, and fever may be the only indicator of severe ...

Last Updated: 31 Dec 1969

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Incidence of neutropenia and use of granulocyte colony-stimulating factors in multiple myeloma: is current clinical practice adequate?
 

Author(s): Xavier Leleu, Francesca Gay, Anne Flament, Kim Allcott, Michel Delforge

Journal: Ann. Hematol.. 2018 Mar;97(3):387-400.

 

Although immunomodulatory drugs, alkylating agents, corticosteroids, protease inhibitors, and therapeutic monoclonal antibodies improve multiple myeloma outcomes, treatment burden is still an issue. Neutropenia is a known complication of cytotoxic cancer therapy and is often associated ...

Last Updated: 31 Dec 1969

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New monogenic disorders identify more pathways to neutropenia: from the clinic to next-generation sequencing.
 

Author(s): Seth J Corey, Usua Oyarbide

Journal: Hematology Am Soc Hematol Educ Program. 2017 12;2017(1):172-180.

 

Neutrophils are the most common type of leukocyte in human circulating blood and constitute one of the chief mediators for innate immunity. Defined as a reduction from a normal distribution of values, neutropenia results from a number of congenital and acquired conditions. Neutropenia ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer
 

Status: Recruiting

Condition Summary: Febrile Neutropenia

 

Last Updated: 31 Jul 2018

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Last Updated: 26 Dec 2017

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