Neutropenia

Common Name(s)

Neutropenia

Neutropenia is a disorder in which individuals have an abnormally low count of neutrophils, a type of white blood cell that helps fight off infections. The low count can be caused by cancer, viral infections, autoimmune disorders or drugs that damage the function of bone marrow or neutrophil cells. The lower the neutrophil count, the more vulnerable an individual is to infection or sickness. Common symptoms of neutropenia include fevers and frequent infections, which can result in mouth ulcers, diarrhea, a burning sensation when urinating, unusual redness, pain, or a sore throat.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neutropenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neutropenia" returned 963 free, full-text research articles on human participants. First 3 results:

Intensity and duration of neutropenia relates to the development of oral mucositis but not odontogenic infection during chemotherapy for hematological malignancy.
 

Author(s): Megumi Kishimoto, Masaya Akashi, Kazuyuki Tsuji, Junya Kusumoto, Shungo Furudoi, Yasuyuki Shibuya, Yumiko Inui, Kimikazu Yakushijin, Shinichiro Kawamoto, Atsuo Okamura, Hiroshi Matsuoka, Takahide Komori

Journal:

 

D-index which combines the intensity and duration of neutropenia is reported as a tool for evaluating the dynamics of neutropenia. This study aimed to analyze the relationship between D-index and oral complications (i.e., oral mucositis [OM] and odontogenic infection [OI]) during ...

Last Updated: 27 Jul 2017

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Efficacy and safety of micafungin versus extensive azoles in the prevention and treatment of invasive fungal infections for neutropenia patients with hematological malignancies: A meta-analysis of randomized controlled trials.
 

Author(s): Cho-Hao Lee, Jung-Chung Lin, Ching-Liang Ho, Min Sun, Wel-Ting Yen, Chin Lin

Journal:

 

Current studies that compare the efficacy and safety of micafungin (MCFG) with that of triazoles for the prophylaxis and treatment of invasive fungal infections (IFIs) demonstrate a lack of sufficient evidence and yield conflicting results. To compare the efficacy and safety of MCFG ...

Last Updated: 12 Jul 2017

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A Rare Case of Adult Autoimmune Neutropenia Successfully Treated with Prednisolone.
 

Author(s): Mari Fujita, Hiroshi Kawabata, Tomomi Oka, Masakatsu Hishizawa, Toshiyuki Kitano, Tadakazu Kondo, Kohei Yamashita, Kimiko Yurugi, Hideyo Hirai, Taira Maekawa, Akifumi Takaori-Kondo

Journal: Intern. Med.. 2017 ;56(11):1415-1419.

 

Autoimmune neutropenia (AIN) is a rare disorder that may cause life-threatening infections. In adults, most cases are secondary to other pathological conditions, and primary AIN is extremely rare. We herein report a case involving a 57-year-old woman diagnosed with AIN. A granulocyte ...

Last Updated: 1 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neutropenia" returned 81 free, full-text review articles on human participants. First 3 results:

[Advances in research on childhood neutropenia].
 

Author(s): Jian-Hua Feng, Yan Qian

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):484-489.

 

Neutrophils, an important type of human immune cells, are involved in host defense against infections. Neutropenia refers to a group of diseases manifesting as a reduction in the absolute value of mature neutrophils and is often accompanied by an increased risk of bacterial infection. ...

Last Updated: 14 Apr 2017

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Neutropenia as an Adverse Event following Vaccination: Results from Randomized Clinical Trials in Healthy Adults and Systematic Review.
 

Author(s): Vincent Muturi-Kioi, David Lewis, Odile Launay, Geert Leroux-Roels, Alessandra Anemona, Pierre Loulergue, Caroline L Bodinham, Annelies Aerssens, Nicola Groth, Allan Saul, Audino Podda

Journal:

 

In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported. It is therefore important to evaluate how these trials should be planned not to miss potentially important safety ...

Last Updated: 5 Aug 2016

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Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction.
 

Author(s): Lise J Estcourt, Simon J Stanworth, Sally Hopewell, Carolyn Doree, Marialena Trivella, Edwin Massey

Journal:

 

Despite modern antimicrobials and supportive therapy bacterial and fungal infections are still major complications in people with prolonged disease-related or treatment-related neutropenia. Transfusions of granulocytes have a long history of usage in clinical practice to support and ...

Last Updated: 2 May 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer
 

Status: Recruiting

Condition Summary: Febrile Neutropenia

 

Last Updated: 19 Oct 2017

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Last Updated: 24 Feb 2017

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