Neutropenia

Common Name(s)

Neutropenia

Neutropenia is a disorder in which individuals have an abnormally low count of neutrophils, a type of white blood cell that helps fight off infections. The low count can be caused by cancer, viral infections, autoimmune disorders or drugs that damage the function of bone marrow or neutrophil cells. The lower the neutrophil count, the more vulnerable an individual is to infection or sickness. Common symptoms of neutropenia include fevers and frequent infections, which can result in mouth ulcers, diarrhea, a burning sensation when urinating, unusual redness, pain, or a sore throat.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neutropenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neutropenia" returned 982 free, full-text research articles on human participants. First 3 results:

Long-Term Effects of G-CSF Therapy in Cyclic Neutropenia.
 

Author(s): David C Dale, AudreyAnna Bolyard, Tracy Marrero, Vahagn Makaryan, MaryAnn Bonilla, Daniel C Link, Peter Newburger, Akiko Shimamura, Laurence A Boxer, Charles Spiekerman

Journal: N. Engl. J. Med.. 2017 12;377(23):2290-2292.

 

Last Updated: 31 Dec 1969

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A Comparison of Brand and Biosimilar Granulocyte-Colony Stimulating Factors for Prophylaxis of Chemotherapy-Induced Febrile Neutropenia.
 

Author(s): Andrea G Douglas, Phil Schwab, Daniel Lane, Kenneth Kennedy, S Lane Slabaugh, Andy Bowe

Journal: J Manag Care Spec Pharm. 2017 Dec;23(12):1221-1226.

 

Filgrastim-sndz, a granulocyte-colony stimulating factor (G-CSF), was introduced as a biosimilar to filgrastim in 2015, but real-world comparative effectiveness for filgrastim versus filgrastim-sndz has not been reported to date.

Last Updated: 31 Dec 1969

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[Nasal phaeohyphomycosis by Curvularia spicifera in pediatric patient with neutropenia and acute myeloid leukemia].
 

Author(s): Constanza Bay, Tamara González, Gonzalo Munoz, Paulette Legarraga, Cecilia Vizcaya, Katia Abarca

Journal: Rev Chilena Infectol. 2017 Jun;34(3):280-286.

 

There are very few reports of pediatric patients with infections by dematiaceous filamentous fungi. In this publication we report a case of invasive fungal infection of the nasal septum by Curvularia spicifera in a pediatric patient with acute myeloid leukemia. The patient presented ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neutropenia" returned 93 free, full-text review articles on human participants. First 3 results:

Incidence of neutropenia and use of granulocyte colony-stimulating factors in multiple myeloma: is current clinical practice adequate?
 

Author(s): Xavier Leleu, Francesca Gay, Anne Flament, Kim Allcott, Michel Delforge

Journal: Ann. Hematol.. 2018 Mar;97(3):387-400.

 

Although immunomodulatory drugs, alkylating agents, corticosteroids, protease inhibitors, and therapeutic monoclonal antibodies improve multiple myeloma outcomes, treatment burden is still an issue. Neutropenia is a known complication of cytotoxic cancer therapy and is often associated ...

Last Updated: 31 Dec 1969

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The Effectiveness of Febrile Neutropenia Prophylaxis with Lipegfilgrastim in Routine Clinical Practice.
 

Author(s): Lubos Holubec, Jiri Polivka, Lenka Lisnerova, Tereza Kubikova, Martin Safanda

Journal: In Vivo. ;31(3):303-306.

 

Febrile neutropenia (FN) is a common and potentially fatal complication of anticancer treatment, particularly in patients receiving myelosuppressive chemotherapy. It has been shown that prophylaxis with granulocyte colony-stimulating factor (G-CSF), especially its pegylated forms, ...

Last Updated: 31 Dec 1969

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[Advances in research on childhood neutropenia].
 

Author(s): Jian-Hua Feng, Yan Qian

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):484-489.

 

Neutrophils, an important type of human immune cells, are involved in host defense against infections. Neutropenia refers to a group of diseases manifesting as a reduction in the absolute value of mature neutrophils and is often accompanied by an increased risk of bacterial infection. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer
 

Status: Recruiting

Condition Summary: Febrile Neutropenia

 

Last Updated: 19 Oct 2017

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Last Updated: 26 Dec 2017

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