Non-Hodgkin lymphoma

Common Name(s)

Non-Hodgkin lymphoma

Non-Hodgkin lymphoma (NHL) may refer to any lymphoma (cancer of the lymph system) that is not Hodgkin lymphoma. The lymph system is a network of lymph tissue connected by vessels. The lymph system is separate from the blood circulatory system. The main types of cells in lymph tissue are lymphocytes which are white blood cells that fight bacteria, viruses and other foreign cells. Lymph tissue includes lymph nodes as well as knots of lymphocytes found in the intestines, spleen and bone marrow. Lymphoma occurs when lymphocytes begin to multiply uncontrollably or become cancerous. These cancerous cells can invade other parts of the body or metastasize. Non-Hodgkin lymphoma is more common than Hodgkin lymphoma. There are different types of NHL depending on if the cancer began in B-cells or T-cells as well as other characteristics.

Symptoms of NHL may include a swelling of the lymph nodes, unexplained fever, night sweats, weight loss, fatigue, and itching. In general the cause of non-Hodgkin lymphomas is unknown. NHL is more common in males and Caucasians. The risk of developing NHL increases with age, certain viral and bacterial infections and exposure to environmental exposure to certain chemicals and pesticides. NHL more often occurs in persons with an autoimmune disease or weakened immune systems such as those with HIV/AIDS or those who have undergone a transplant.

Lymphomas are generally diagnosed through a biopsy of the lymph nodes and sometimes a biopsy of the bone marrow. Other tests may be performed to determine where the cancer is located and how far it has spread. Treatment is similar to that of other cancers and may include radiation, chemotherapy, targeted therapy or a stem cell transplant. Treatment and prognosis depend upon the type and stage of NHL. If you or a family member has been diagnosed with non-Hodgkin lymphoma, talk with your doctor and specialists about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Non-Hodgkin lymphoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

View Details
National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Non-Hodgkin lymphoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Non-Hodgkin lymphoma" returned 948 free, full-text research articles on human participants. First 3 results:

Weekly versus biweekly bortezomib given in patients with indolent non-Hodgkin lymphoma: A meta-analysis.
 

Author(s): Ting Yuan, Feng Zhang, Qing-Min Yao, Yan-Xia Liu, Xiao-Juan Zhu, Xin Wang

Journal:

 

Bortezomib is recently studied as a novel agent in indolent lymphoma. The optimal schedule of bortezomib used in indolent lymphoma is still uncertain.

Last Updated: 22 May 2017

Go To URL
Emergency admission and survival from aggressive non-Hodgkin lymphoma: A report from the UK's population-based Haematological Malignancy Research Network.
 

Author(s): Eleanor Kane, Debra Howell, Alexandra Smith, Simon Crouch, Cathy Burton, Eve Roman, Russell Patmore

Journal: Eur. J. Cancer. 2017 Jun;78():53-60.

 

Non-Hodgkin lymphoma (NHL) is often diagnosed after emergency presentation, a route associated with poor survival and an indicator of diagnostic delay. Accounting for around half of all NHLs, diffuse large B-cell lymphoma (DLBCL) is of particular interest since although it is potentially ...

Last Updated: 16 Apr 2017

Go To URL
Prognostic significance of latent membrane protein 1 expression in non-Hodgkin lymphoma: A meta-analysis.
 

Author(s): Xiao-Mei Li, Wen-Hua Xiao, Hui-Xia Zhao

Journal: Medicine (Baltimore). 2017 Apr;96(14):e6512.

 

The prognostic value of latent membrane protein 1 (LMP1) in non-Hodgkin lymphoma (NHL) has been evaluated in several studies. However, the conclusions remain controversial.

Last Updated: 6 Apr 2017

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Non-Hodgkin lymphoma" returned 83 free, full-text review articles on human participants. First 3 results:

Model-based meta-analysis of progression-free survival in non-Hodgkin lymphoma patients.
 

Author(s): Mengyao Li, Nimita Dave, Ahmed Hamed Salem, Kevin J Freise

Journal: Medicine (Baltimore). 2017 Sep;96(35):e7988.

 

Non-Hodgkin lymphoma (NHL) is a group of lymphoproliferative malignancies with varying treatment responses and progression-free survival (PFS) times. The objective of this study was to quantify the effect of treatment and patient-population characteristics on PFS in patients with NHL.

Last Updated: 31 Aug 2017

Go To URL
Primary adrenal non-Hodgkin lymphoma: a case report and review of the literature.
 

Author(s): Nanik Ram, Owais Rashid, Saad Farooq, Imran Ulhaq, Najmul Islam

Journal:

 

Lymphomas are cancers that arise from the white blood cells and have been traditionally divided into two large subtypes: Hodgkin and non-Hodgkin lymphoma. B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma; almost 85% of patients with lymphoma have this variant. Lymphomas ...

Last Updated: 15 Apr 2017

Go To URL
Clinical development of anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma.
 

Author(s): Shinichi Makita, Kiyoshi Yoshimura, Kensei Tobinai

Journal: Cancer Sci.. 2017 Jun;108(6):1109-1118.

 

B-cell non-Hodgkin lymphoma (B-NHL) is the most frequent hematological malignancy. Although refined chemotherapy regimens and several new therapeutics including rituximab, a chimeric anti-CD20 monoclonal antibody, have improved its prognosis in recent decades, there are still a substantial ...

Last Updated: 16 Mar 2017

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 13 Oct 2016

Go to URL
Study of Chiauranib in Relapsed/Refractory Non-Hodgkin's Lymphoma
 

Status: Recruiting

Condition Summary: Non-Hodgkin's Lymphoma

 

Last Updated: 23 May 2017

Go to URL
To Compare the Efficacy of a Prophylactic Use of Tenofovir by Duration for the Non-Hodgkin's Lymphoma
 

Status: Recruiting

Condition Summary: Non-Hodgkin's Lymphoma, Burkitt's

 

Last Updated: 20 Dec 2016

Go to URL