Obesity

Common Name(s)

Obesity

Obesity is a condition characterized by the build up of excessive body fat. Obesity is defined differently depending on the country, but in Western countries, such as the U.S. and many European countries, obesity is defined as a body mass index (BMI) of 30 kg/m^2.

A BMI is calculated by taking a person's weight (in kilograms) and dividing it by the square of their height (in meters). Using the BMI, doctors may classify someone as underweight, normal weight, overweight, or obese. Obesity is further broken down into three categories. First, obesity I is measured as a BMI of 30-34.99 kg/m^2, obesity II is 35-39.99 kg/m^2, and obesity III is a BMI greater than 40 kg/m^2. It is important to note that these values are only recognized for adults (18+ years old). In adolescents, different scales are used based on a number of factors.

There are many potential causes for obesity such as environmental, genetic, or both. Contributing factors that may lead to obesity include a poor diet, little or no exercise, infections, and certain genetic conditions. Other contributing factors may include some social determinants such as socioeconomic class and geographic location. In any case, obesity can lead to serious health problems, including a lower life expectancy. On average, obesity can reduce an individual's life expectancy by six to seven years. Obesity may also lead to an increased risk for many conditions including type II diabetes, heart diseases, stroke, many cancers, gastrointestinal conditions, abnormal or poor breathing, depression, and more.

Generally, obesity is treated with certain lifestyle changes such as diet plans and making exercise routines. Medications and surgeries may also be an option depending on the cause of the obesity, its severity, and the individual's choices. If you or someone you know has been diagnosed with obesity, contact your doctor to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obesity" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

Last Updated: 14 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obesity" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

http://www.bardetbiedl.org/

Last Updated: 14 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Obesity" returned 12729 free, full-text research articles on human participants. First 3 results:

Association between obesity with disease-free survival and overall survival in triple-negative breast cancer: A meta-analysis.
 

Author(s): Lin Mei, Lin He, Yuhua Song, Yang Lv, Lijiu Zhang, Fengxi Hao, Mengmeng Xu

Journal: Medicine (Baltimore). 2018 May;97(19):e0719.

 

To investigate the relationship between obesity and disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer.

Last Updated: 31 Dec 1969

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Health Care Provider Counseling for Weight Loss Among Adults with Arthritis and Overweight or Obesity - United States, 2002-2014.
 

Author(s): Dana Guglielmo, Jennifer M Hootman, Louise B Murphy, Michael A Boring, Kristina A Theis, Brook Belay, Kamil E Barbour, Miriam G Cisternas, Charles G Helmick

Journal:

 

In the United States, 54.4 million adults report having doctor-diagnosed arthritis (1). Among adults with arthritis, 32.7% and 38.1% also have overweight and obesity, respectively (1), with obesity being more prevalent among persons with arthritis than among those who do not have ...

Last Updated: 31 Dec 1969

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COMPARISON OF THE LEVELS OF C-REACTIVE PROTEIN, GLP-1 AND GLP-2 AMONG INDIVIDUALS WITH DIABETES, MORBID OBESITY AND HEALTHY CONTROLS: AN EXPLORATORY STUDY.
 

Author(s): Everton Cazzo, José Carlos Pareja, Elinton Adami Chaim, Cláudio Saddy Rodrigues Coy, Daniéla Oliveira Magro

Journal: Arq Gastroenterol. ;55(1):72-77.

 

The glucagon-like peptides 1 and 2 (GLP-1/GLP-2) are gut hormones that may directly affect the glucose homeostasis and their activity seems to be significantly affected by chronic inflammation.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Obesity" returned 2667 free, full-text review articles on human participants. First 3 results:

Effectiveness of testosterone therapy in obese men with low testosterone levels, for losing weight, controlling obesity complications, and preventing cardiovascular events: Protocol of a systematic review of randomized controlled trials.
 

Author(s): Amanda S Mangolim, Leonardo A R Brito, Vania S Nunes-Nogueira

Journal: Medicine (Baltimore). 2018 Apr;97(17):e0482.

 

The use of testosterone replacement therapy in obese men with low testosterone levels has been controversial. This review aims to analyze the effectiveness of testosterone therapy for weight loss and preventing cardiovascular complications in obese men with low testosterone levels.

Last Updated: 31 Dec 1969

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Efficacy, safety, and mechanisms of herbal medicines used in the treatment of obesity: A protocol for systematic review.
 

Author(s): Moloud Payab, Shirin Hasani-Ranjbar, Azadeh Aletaha, Nasrin Ghasemi, Mostafa Qorbani, Rasha Atlasi, Mohammad Abdollahi, Bagher Larijani

Journal: Medicine (Baltimore). 2018 Jan;97(1):e8825.

 

This systematic review protocol aims to perform a protocol for assessing the effectiveness, safety, and mechanism of herbal medicines for the treatment of obesity and metabolic syndrome. Some systematic reviews conducted earlier have evaluated the efficacy of herbal medicine to treat ...

Last Updated: 31 Dec 1969

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[Pharmacological Mechanisms of Boiogito and Bofutsushosan in Diabetes and Obesity Models].
 

Author(s): Shinjiro Kobayashi

Journal: Yakugaku Zasshi. 2018 ;138(3):389-403.

 

 The antihyperglycemic activities of extracts of boiogito (BOT) and bofutsushosan (BTS) were investigated in streptozotocin-induced (STZ)-diabetic mice. BOT extract containing Stephania tetrandra S. MOORE root (stephania), has more potent antihyperglycemic activity than BOT extract ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Individualized Obesity Pharmacotherapy
 

Status: Recruiting

Condition Summary: Obesity

 

Last Updated: 11 Dec 2017

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Last Updated: 9 Mar 2017

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