Occult macular dystrophy

Common Name(s)

Occult macular dystrophy

Occult macular dystrophy is characterized by progressive decline of visual acuity in both eyes, associated with a normal fundus and normal fluorescein angiography. Patients have normal full-field electroretinograms (ERGs) but severely reduced focal macular ERGs, as recorded by conventional techniques using small stimuli under background illumination. OCMD patients are believed to have localized retinal dysfunction distal to the ganglion cells in the central retina (summary by {9:Piao et al., 2000}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Occult macular dystrophy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Occult macular dystrophy" returned 7 free, full-text research articles on human participants. First 3 results:

Structure-functional correlation using adaptive optics, OCT, and microperimetry in a case of occult macular dystrophy.
 

Author(s): Karlos Ítalo Viana, André Messias, Rubens Camargo Siqueira, Murilo W Rodrigues, Rodrigo Jorge

Journal: Arq Bras Oftalmol. ;80(2):118-121.

 

We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive ...

Last Updated: 31 Dec 1969

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Characterizing the phenotype and genotype of a family with occult macular dystrophy.
 

Author(s): Connie J Chen, Hendrik P N Scholl, David G Birch, Takeshi Iwata, Neil R Miller, Morton F Goldberg

Journal: Arch. Ophthalmol.. 2012 Dec;130(12):1554-9.

 

To characterize the phenotype of a white patient with occult macular dystrophy (OMD) and her clinically unaffected family members and to determine whether similar mutations were present in the RP1L1 gene in this family. Occult macular dystrophy is a rare macular dystrophy with central ...

Last Updated: 31 Dec 1969

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A new mutation in the RP1L1 gene in a patient with occult macular dystrophy associated with a depolarizing pattern of focal macular electroretinograms.
 

Author(s): Takenori Kabuto, Hisatomo Takahashi, Yoko Goto-Fukuura, Tsutomu Igarashi, Masakazu Akahori, Shuhei Kameya, Takeshi Iwata, Atsushi Mizota, Kunihiko Yamaki, Yozo Miyake, Hiroshi Takahashi

Journal: Mol. Vis.. 2012 ;18():1031-9.

 

To determine whether a mutation in the RP1-like protein 1 (RP1L1) gene is present in a Japanese patient with sporadic occult macular dystrophy (OMD) and to examine the characteristics of focal macular electroretinograms (ERGs) of the patient with genetically identified OMD.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Occult macular dystrophy" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

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