Ollier disease

Common Name(s)

Ollier disease, Enchondromatosis

Ollier disease, also known as enchondromatosis, is a disorder that leads to the growth of non-cancerous tumors in cartilage. Cartilage is a type of tissue that is found inside of bones and is involved in bone growth. The most common location where Ollier disease develops is the long bones of the body, specifically in the arms and legs. Although less common, tumors can also grow in the pelvic bone, ribs, breastbone, and skull. Tumors form when a change (mutation) in DNA causes certain cells to grow out of control, resulting in the formation of a mass or a lump.

Ollier disease is present from the time of birth, and symptoms usually first appear between the ages of 1 and 10. The most common signs of Ollier disease include short limbs and bowing, or bending, of long bones which may cause difficulty walking. This disorder may cause problems with bone growth, which may result in pain and frequent fractures in the affected areas. Diagnosis may involve a physical exam, imaging studies, and other laboratory studies such as bone scans.

Treatment for Ollier disease depends on many factors such as how large the tumors are and their locations in the body. If you or a family member has been diagnosed with Ollier disease, talk to your doctor about the most current treatment options. Support groups are also available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ollier disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ollier disease" returned 13 free, full-text research articles on human participants. First 3 results:

The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease).
 

Author(s): Andrea Burgetova, Zdenek Matejovsky, Michal Zikan, Jiri Slama, Pavel Dundr, Petr Skapa, Kamila Benkova, David Cibula, Daniela Fischerova

Journal: Taiwan J Obstet Gynecol. 2017 Apr;56(2):253-257.

 

Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these conditions. Besides the association with ...

Last Updated: 31 Dec 1969

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Ollier disease in a 6-year-old child.
 

Author(s): Conor Gouk, Luca Daniele, Craig Buchan

Journal:

 

Last Updated: 31 Dec 1969

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Clinical images: enchondromatosis (Ollier disease).
 

Author(s): Milena Cerny, Hannes A Rudiger, Berengere Aubry-Rozier, Eric Dugert, Fabio Becce

Journal: Arthritis Rheum.. 2013 Nov;65(11):2886.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ollier disease" returned 1 free, full-text review articles on human participants. First 3 results:

Ollier disease.
 

Author(s): Caroline Silve, Harald J├╝ppner

Journal:

 

Enchondromas are common intraosseous, usually benign cartilaginous tumors, that develop in close proximity to growth plate cartilage. When multiple enchondromas are present, the condition is called enchondromatosis also known as Ollier disease (WHO terminology). The estimated prevalence ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

An Efficacy and Safety Study of Palovarotene for the Treatment of MO
 

Status: Recruiting

Condition Summary: Exostoses, Multiple Hereditary

 

Last Updated: 25 Apr 2018

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