Optic neuritis

Common Name(s)

Optic neuritis

Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.  The condition may cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis, drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Optic neuritis" returned 325 free, full-text research articles on human participants. First 3 results:

Typical optic neuritis?
 

Author(s): Jyoti Matalia, Shoruba Dinakaran, Hemant Anaspure

Journal: Indian J Ophthalmol. 2018 07;66(7):895.

 

Last Updated: 31 Dec 1969

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Possible Combined Central and Peripheral Demyelination Presenting as Optic Neuritis, Cervical Myelitis, and Demyelinating Polyneuropathy with Marked Nerve Hypertrophy.
 

Author(s): Yasutaka Tajima, Mariko Matsumura, Hiroaki Yaguchi, Yasunori Mito

Journal: Intern. Med.. 2018 ;57(6):867-871.

 

A 27-year-old woman with optic neuritis and cervical myelitis developed hypertrophic demyelinating polyneuropathy. It was hypothesized that the diagnosis was combined central and peripheral demyelination. A hypertrophic nerve was observed subcutaneously, and magnetic resonance imaging ...

Last Updated: 31 Dec 1969

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Retinal nerve fiber layer and ganglion cell layer changes on optical coherence tomography in early multiple sclerosis and optic neuritis cases.
 

Author(s): Ganesh Pillay, Anita Ganger, Digvijay Singh, Rohit Bhatia, Pradeep Sharma, Vimla Menon, Rohit Saxena

Journal: Indian J Ophthalmol. 2018 01;66(1):114-119.

 

To study the retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) changes on optical coherence tomography in early multiple sclerosis (MS) patients.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Optic neuritis" returned 30 free, full-text review articles on human participants. First 3 results:

Neuromyelitis Optica: Review and Utility of Testing Aquaporin-4 Antibody in Typical Optic Neuritis.
 

Author(s): Meagan Seay, Janet C Rucker

Journal: Asia Pac J Ophthalmol (Phila). ;7(4):229-234.

 

Neuromyelitis optica (NMO) is an autoimmune, inflammatory demyelinating disorder often leading to severe vision impairment and disability. The discovery of a diagnostic biomarker, the aquaporin-4 antibody (AQP4-IgG), transformed the clinical diagnosis and treatment of NMO and broadened ...

Last Updated: 31 Dec 1969

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Updates and Controversies in the Management of Acute Optic Neuritis.
 

Author(s): Ethan Meltzer, Sashank Prasad

Journal: Asia Pac J Ophthalmol (Phila). ;7(4):251-256.

 

Optic neuritis remains a common diagnosis with controversial management. Although typical optic neuritis is often associated with "good" recovery of visual acuity, patients are often left with persistent impairments of contrast sensitivity, color vision, and visual field. These permanent ...

Last Updated: 31 Dec 1969

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Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis.
 

Author(s): Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Takahiko Noro, Chikako Harada, Takayuki Harada

Journal: Oxid Med Cell Longev. 2017 ;2017():2817252.

 

Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells (RGCs) and their axons, namely, the optic nerve, usually associated with elevated intraocular pressure ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

High-Dose Vitamin D Induction in Optic Neuritis
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 30 Nov 2017

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Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic Neuritis
 

Status: Not yet recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 2 Jul 2018

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