Oral candidiasis

Common Name(s)

Oral candidiasis, Oral thrush

Oral thrush, or oral candidiasis, is an infection of the mouth that is caused by a fungus called Candida albicans, a type of yeast. Yeast is normally present in our mouths, but if there is too much it may cause problems. Yeast infections are also seen in other parts of the body and may cause vaginal infections or diaper rash.

The major symptom of oral thrush is white cottage cheese like lesions on the inside of the mouth. These lesions can be anywhere in the mouth, but are often found on the tongue or inside of the cheeks. The lesions may be very painful. The redness and soreness may make it difficult to eat or swallow. The lesions may also bleed if rubbed too hard. Oral thrush can lead to loss of taste. The infection may spread to the esophagus, the tube which takes food from your mouth to your stomach.

Anyone can have thrush, but it is most often found in babies, the elderly and anyone with a weakened immune system. Babies may transfer the infection to their mother during breastfeeding. Wearing dentures which do not fit well, smoking or having a condition that causes a dry mouth can increase your chance of developing thrush. Other risk factors include taking antibiotics, oral birth control, or using an inhaler for asthma. Certain medical issues such as HIV/AIDS, cancer, or diabetes not only increase your risk of developing thrush but also increases the risk of developing a systemic candida infection and make thrush more difficult to treat.

Diagnosis is usually made by examining the lesions in the mouth. Blood tests may be performed to determine why thrush occurred. Treatment depends on the age and health of the individual but usually includes antifungal medication. Different medications may be needed if the person has a weakened immune system. Changes in diet may also be recommended. If you or a family member has thrush, talk to a doctor about the most current treatment options.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral candidiasis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oral candidiasis" returned 100 free, full-text research articles on human participants. First 3 results:

Clinical and laboratorial features of oral candidiasis in HIV-positive patients.
 

Author(s): Regiane Nogueira Spalanzani, Karine Mattos, Luiza Inahe Marques, Pedro Fernando Diniz Barros, Pamela Iruama Peres Pereira, Anamaria Mello Miranda Paniago, Rinaldo Poncio Mendes, Marilene Rodrigues Chang

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):352-356.

 

We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients.

Last Updated: 31 Dec 1969

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Antifungal activity of linalool in cases of Candida spp. isolated from individuals with oral candidiasis.
 

Author(s): I J Dias, E R I S Trajano, R D Castro, G L S Ferreira, H C M Medeiros, D Q C Gomes

Journal: Braz J Biol. 2018 May;78(2):368-374.

 

This study analyzed the antifungal activity of phytoconstituents from linalool on Candida spp. strains, in vitro, isolated from patients with clinical diagnoses of oral candidiasis associated with the use of a dental prosthesis. Biological samples were collected from 12 patients using ...

Last Updated: 31 Dec 1969

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Quantity of Candida Colonies in Saliva: 
A Diagnostic Evaluation for Oral Candidiasis.
 

Author(s): Pei Ru Zhou, Hong Hua, Xiao Song Liu

Journal: Chin J Dent Res. ;20(1):27-32.

 

To investigate the relationship between the quantity of Candida colonies in saliva and oral candidiasis (OC), as well as to identify the threshold for distinguishing oral candidiasis from healthy carriage.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oral candidiasis" returned 8 free, full-text review articles on human participants. First 3 results:

Treatment and Prevention of Oral Candidiasis in Elderly Patients.
 

Author(s): Hideo Sakaguchi

Journal: Med Mycol J. 2017 ;58(2):J43-J49.

 

The incidence of oral candidiasis has increased in the elderly in recent years. Although the increase of the elderly population plays a big role in this rise of oral candidiasis, the broader recognition that elderly people have higher infection rates for oral candidiasis is considered ...

Last Updated: 31 Dec 1969

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Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis.
 

Author(s): Xin Lyu, Chen Zhao, Zhi-Min Yan, Hong Hua

Journal:

 

To systematically review and assess the efficacy, different treatment protocols (formulation, dosage, and duration), and safety of nystatin for treating oral candidiasis.

Last Updated: 31 Dec 1969

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Recent mouse and rat methods for the study of experimental oral candidiasis.
 

Author(s): Anna C B P Costa, Cristiane A Pereira, Juliana C Junqueira, Antonio O C Jorge

Journal: Virulence. 2013 Jul;4(5):391-9.

 

The Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida and the elucidation of the disease process have proven challenging. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Oral VT-1161 for the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
 

Status: Recruiting

Condition Summary: Recurrent Vulvovaginal Candidiasis

 

Last Updated: 16 Aug 2018

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A Study of Oral VT-1161 for the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
 

Status: Not yet recruiting

Condition Summary: Recurrent Vulvovaginal Candidiasis

 

Last Updated: 25 Jun 2018

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Efficacy and Safety of Oral Encochleated Amphotericin B (CAMB) in the Treatment of Fluconazole-Resistant Vulvovaginal Candidiasis
 

Status: Not yet recruiting

Condition Summary: Vulvovaginal Candidiases; Yeast Infection; Vulvovaginitis; Yeast Infection Vaginal; Candidiasis, Vulvovaginal

 

Last Updated: 11 Jun 2018

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