Osteoarthritis

Common Name(s)

Osteoarthritis

Osteoarthritis is one of the most common forms of arthritis. It is a chronic condition in which the material that cushions the joints, called cartilage, breaks down. This causes the bones to rub against each other, causing stiffness, pain and loss of joint movement. Common symptoms are sore or stiff joints, particularly the hips, knees, and lower back, but osteoarthritis may also affect the neck, small finger joints, the base of the thumb, ankle, and big toe. The pain may be moderate and come and go, without affecting the ability to perform daily tasks. Some people’s OA will never progress past this early stage. Others will have their OA get worse. The pain and stiffness of more severe osteoarthritis may make it difficult to walk, climb stairs, sleep, or perform other daily tasks.

About 27 million people in the United States have osteoarthritis. The cause is not fully understood and no cure exists but osteoarthritis treatments can slow the progression of the disease, relieve pain and improve joint function. Common risk factors include increasing age, obesity, previous joint injury, overuse of the joint, weak thigh muscles, and genetics.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoarthritis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoarthritis" returned 5141 free, full-text research articles on human participants. First 3 results:

Extracorporeal shock wave treatment can normalize painful bone marrow edema in knee osteoarthritis: A comparative historical cohort study.
 

Author(s): Shuhua Kang, Fuqiang Gao, Jun Han, Tianli Mao, Wei Sun, Bailiang Wang, Wanshou Guo, Liming Cheng, Zirong Li

Journal: Medicine (Baltimore). 2018 Feb;97(5):e9796.

 

Bone marrow edema (BME) represents a reversible but highly painful finding in magnetic resonance imaging (MRI) of patients with knee osteoarthritis. The aim of this retrospective study was to evaluate the efficacy of extracorporeal shock wave treatment (ESWT) on painful BME in osteoarthritis ...

Last Updated: 31 Dec 1969

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Genotype and clinical course in 2 Chinese Han siblings with Wilson disease presenting with isolated disabling premature osteoarthritis: A case report.
 

Author(s): Siyuan Ye, Tingjun Dai, Bingquan Leng, Lei Tang, Liang Jin, Lili Cao

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8641.

 

Premature osteoarthritis (POA) is a rare condition in Wilson disease (WD). Particularly, when POA is the only complaint of a WD patient for a long time, there would be misdiagnosis or missed diagnosis and then treatment delay.

Last Updated: 31 Dec 1969

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Prevalence of hand osteoarthritis and knee osteoarthritis in Kashin-Beck disease endemic areas and non Kashin-Beck disease endemic areas: A status survey.
 

Author(s): Wei Lian, Hui Liu, QuanQuan Song, Yun Qi Liu, Li Yan Sun, Qing Deng, Shao Ping Wang, Yan Hong Cao, Xue Ying Zhang, Yuan Yuan Jiang, Hong Yan Lv, Li Bin Duan, Jun Yu

Journal:

 

Osteoarthritis (OA) is a considerable health problem worldwide, and the prevalence of OA varies in different regions. In this study, the prevalence of OA in Kashin-Beck disease (KBD) and non-KBD endemic areas was examined, respectively. According to monitoring data, 4 types of regions ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoarthritis" returned 816 free, full-text review articles on human participants. First 3 results:

Traditional Chinese medicine for knee osteoarthritis: An overview of systematic review.
 

Author(s): Min Yang, Li Jiang, Qing Wang, Hao Chen, Guihua Xu

Journal:

 

Traditional Chinese medicine (TCM) has been accepted as a complementary therapy for knee osteoarthritis. However, the efficacy and safety of the intervention were still conflicting and uncertain. Meanwhile, the quality of methodology and evidence in the field was unknown.

Last Updated: 31 Dec 1969

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Association of BMP-14 rs143383 ploymorphism with its susceptibility to osteoarthritis: A meta-analysis and systematic review according to PRISMA guideline.
 

Author(s): Yi Yin, Yan Wang

Journal: Medicine (Baltimore). 2017 Oct;96(42):e7447.

 

Osteoarthritis (OA) is a complex disease which can be caused by both environmental and genetic factors. A functional locus rs143383 of bone morphogenetic protein-14 (BMP-14) has been pointed out to be associated with OA etiology, but conflicting conclusions have been reached. To provide ...

Last Updated: 31 Dec 1969

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A Fresh Perspective on a Familiar Problem: Examining Disparities in Knee Osteoarthritis Using a Markov Model.
 

Author(s): Taruja D Karmarkar, Anne Maurer, Michael L Parks, Thomas Mason, Ana Bejinez-Eastman, Melvyn Harrington, Randall Morgan, Mary I O'Connor, James E Wood, Darrell J Gaskin

Journal: Med Care. 2017 Dec;55(12):993-1000.

 

Disparities in the presentation of knee osteoarthritis (OA) and in the utilization of treatment across sex, racial, and ethnic groups in the United States are well documented.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Feasibility of High Intensity Interval Training in Knee Osteoarthritis
 

Status: Recruiting

Condition Summary: Knee Osteoarthritis

 

Last Updated: 11 Dec 2017

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The Study to Evaluate Efficacy and Safety of Celecoxib Capsule in Hand Osteoarthritis Patients
 

Status: Recruiting

Condition Summary: Osteoarthritis Hand

 

Last Updated: 24 Feb 2017

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Self-administered Acupressure for Knee Osteoarthritis: A Pilot Randomized Controlled Trial
 

Status: Recruiting

Condition Summary: Knee Osteoarthritis

 

Last Updated: 4 Aug 2017

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