Osteopoikilosis

Common Name(s)

Osteopoikilosis

Osteopoikilosis is a condition in which many small, roundish spots are found in the bones, particularly near the joints.  These spots are areas of bone tissue that did not develop properly and are exceptionally dense.  They usually do not cause symptoms and do not change over time.  Osteopoikilosis can be diagnosed at any age and is often detected by chance when an otherwise healthy individual has x-rays for an unrelated reason, such as injury.  This condition may occur randomly with no other features (sporadic), or may be inherited from a parent as a part of Buschke Ollendorff syndrome.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteopoikilosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteopoikilosis" returned 22 free, full-text research articles on human participants. First 3 results:

Osteopoikilosis found incidentally in a 17-year-old adolescent with femoral shaft fracture: A case report.
 

Author(s): Conglin Ye, Qi Lai, Shengtao Zhang, Tian Gao, Jin Zeng, Min Dai

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8650.

 

Osteopoikilosis is a rare and asymptomatic disease of the bone, which is often discovered occasionally on radiography for irrelevant complaints. Characterized by multiple, small, circular, or oval-shaped radiodense lesions, it may be confused with bony metastatic tumors.

Last Updated: 31 Dec 1969

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Novel 4-bp Intronic Deletion (c.1560+3_1560+6del) in LEMD3 in a Korean Patient With Osteopoikilosis.
 

Author(s): In Young Yoo, Ju Sun Song, Chang Seok Ki, Jong Won Kim, Hoon Suk Cha, Yong Ki Min

Journal: Ann Lab Med. 2017 Nov;37(6):540-543.

 

Osteopoikilosis is an autosomal dominant bone disorder characterized by symmetric multiple osteosclerotic lesions throughout the axial and appendicular skeleton. Pathogenic variants in the LEMD3 have been identified as the cause of osteopoikilosis. LEMD3 encodes an inner nuclear membrane ...

Last Updated: 31 Dec 1969

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Gastric cancer bone metastases together with osteopoikilosis diagnosed using bone scintigraphy and F-FDG PET/CT.
 

Author(s): S Prado Wohlwend, R Sánchez Vaño, P Sopena Novales, E Uruburu García, F Aparisi Rodríguez, C Martínez Carsí

Journal: Rev Esp Med Nucl Imagen Mol. ;36(3):189-193.

 

The coexistence of different bone diseases in the same patient involves a complex differential diagnosis. A patient is presented who was studied due to a renal mass that showed many sclerotic lesions in spine and limbs in conventional radiology and CT. These lesions were evaluated ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteopoikilosis" returned 2 free, full-text review articles on human participants. First 3 results:

Benign incidental findings of osteopoikilosis on Tc-99m MDP bone SPECT/CT: A case report and literature review.
 

Author(s): Szu-Ying Tsai, Shan-Ying Wang, Yu-Chien Shiau, Yen-Wen Wu

Journal: Medicine (Baltimore). 2016 Jun;95(23):e3868.

 

Osteopoikilosis is a benign but rare condition characterized by bone islands throughout the osseous tissue, which could be easily confused with bone metastasis. We present a case of a 37-year-old man presented to orthopedic outpatient clinic with right hip pain for 2 weeks. There ...

Last Updated: 31 Dec 1969

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LEMD3: the gene responsible for bone density disorders (osteopoikilosis).
 

Author(s): Edna Ben-Asher, Elazar Zelzer, Doron Lancet

Journal: Isr. Med. Assoc. J.. 2005 Apr;7(4):273-4.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.