Osteoporosis

Common Name(s)

Osteoporosis

Osteoporosis is a condition that causes bones to become weak and brittle. Bone is living tissue that is constantly being broken down and replaced. When you are young, your body typically makes new bone faster than it breaks down old bone. This leads to dense bone mass (strong bones). When the creation of new bone is unable to keep up with the removal of old bone, they become weak and brittle. If osteoporosis is severe enough, a crack or break (fracture) within the bone can occur from something as minor as a fall or even from a normal action, like coughing. Symptoms of osteoporosis may include back pain, decrease in height, a hunched posture, and increased risk of bone fractures.

Most people reach their peak bone mass by their early 20s. Individuals with a high peak bone mass when they are young have a lower chance of developing osteoporosis as they age. Gender, age, and race are all risk factors for developing osteoporosis. Women, individuals who are white or of Asian descent, and the elderly have an increased risk of developing osteoporosis. Low calcium intake, eating disorders, and gastrointestinal surgery can also cause a greater risk for osteoporosis. Certain medications, especially steroids, as well as tobacco use, excessive alcohol consumption and a sedentary lifestyle all increase the risk for osteoporosis.

Specific types of X-ray images, called DXA scans, may be used to determine your bone density and diagnose osteoporosis. There are many forms of treatment, depending on the severity. It is important to talk to your doctor, if you or someone you know has been diagnosed with osteoporosis, to review the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoporosis" returned 2588 free, full-text research articles on human participants. First 3 results:

Liuwei Dihuang pill cures postmenopausal osteoporosis with kidney-Yin deficiency: Potential therapeutic targets identified based on gene expression profiling.
 

Author(s): Feng Xu, Feng Gao

Journal: Medicine (Baltimore). 2018 Aug;97(31):e11659.

 

This study aimed to investigate the potential therapeutic targets of Liuwei Dihuang pill (LDP) in the treatment of postmenopausal osteoporosis with kidney-Yin deficiency (PMO-KY).Gene expression data were downloaded from the GEO database, including 4 PMO-KY samples and 3 healthy postmenopausal ...

Last Updated: 31 Dec 1969

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Effect of improved medication adherence on health care costs in osteoporosis patients.
 

Author(s): Hyemin Cho, Ji-Hye Byun, Inmyung Song, Ha Y Kim, Yong-Chan Ha, Tae-Young Kim, Young-Kyun Lee, Sunmee Jang

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11470.

 

Osteoporosis is a chronic disease that requires continuous health care spending for pharmacotherapy and examinations. Osteoporotic fractures are a major economic burden. However, little is known about the economic effects of osteoporosis and osteoporotic fractures in Korea.The purpose ...

Last Updated: 31 Dec 1969

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Factors related with osteoporosis treatment in postmenopausal women.
 

Author(s): Lia Mara Montagner Rossi, Rafaela Martinez Copes, Leo Canterle Dal Osto, Clovis Flores, F√°bio Vasconcellos Comim, Melissa Orlandin Premaor

Journal: Medicine (Baltimore). 2018 Jul;97(28):e11524.

 

Although fractures had high mortality and morbidity, many studies proved that fracture risk might be decreased by pharmacological therapy, although a low treatment adherence rate is observed. The aim of this study was to identify factors associated with osteoporosis treatment in postmenopausal ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoporosis" returned 702 free, full-text review articles on human participants. First 3 results:

Effect of balance training on falls in patients with osteoporosis: A systematic review and meta-analysis.
 

Author(s): Xin Zhou, Hui Deng, Xiaoping Shen, Qingliang Lei

Journal: J Rehabil Med. 2018 Jul;50(7):577-581.

 

Balance training may be beneficial for patients with osteoporosis, although current results are inconclusive. The aim of this systematic review and meta-analysis was to explore the effect of balance training on falls in patients with osteoporosis.

Last Updated: 31 Dec 1969

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Prevention and Treatment of Osteoporosis Using Chinese Medicinal Plants: Special Emphasis on Mechanisms of Immune Modulation.
 

Author(s): Hongyan Zhao, Ning Zhao, Peng Zheng, Xiaohong Xu, Meijie Liu, Dan Luo, Huihui Xu, Dahong Ju

Journal:

 

Numerous studies have examined the pathogenesis of osteoporosis. The causes of osteoporosis include endocrine factors, nutritional status, genetic factors, physical factors, and immune factors. Recent osteoimmunology studies demonstrated that the immune system and immune factors play ...

Last Updated: 31 Dec 1969

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Animal versus plant protein and adult bone health: A systematic review and meta-analysis from the National Osteoporosis Foundation.
 

Author(s): Marissa M Shams-White, Mei Chung, Zhuxuan Fu, Karl L Insogna, Micaela C Karlsen, Meryl S LeBoff, Sue A Shapses, Joachim Sackey, Jian Shi, Taylor C Wallace, Connie M Weaver

Journal:

 

Protein may have both beneficial and detrimental effects on bone health depending on a variety of factors, including protein source.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Apr 2018

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Jogging in the Change of Osteoporosis
 

Status: Not yet recruiting

Condition Summary: Osteoporosis

 

Last Updated: 29 Nov 2017

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Multicenter Cohort Study on Osteoporosis
 

Status: Recruiting

Condition Summary: Osteoporosis

 

Last Updated: 16 Apr 2018

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