Oxalate Stone Disease

Common Name(s)

Oxalate Stone Disease

Description for this condition is not yet available.
 

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Condition Specific Organizations

Following organizations serve the condition "Oxalate Stone Disease" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oxalate Stone Disease" returned 6 free, full-text research articles on human participants. First 3 results:

Analysis of altered microRNA expression profiles in proximal renal tubular cells in response to calcium oxalate monohydrate crystal adhesion: implications for kidney stone disease.
 

Author(s): Bohan Wang, Bolin Wu, Jun Liu, Weimin Yao, Ding Xia, Lu Li, Zhiqiang Chen, Zhangqun Ye, Xiao Yu

Journal:

 

Calcium oxalate monohydrate (COM) is the major crystalline component in kidney stones and its adhesion to renal tubular cells leads to tubular injury. However, COM-induced toxic effects in renal tubular cells remain ambiguous. MicroRNAs (miRNAs) play an important role in gene regulation ...

Last Updated: 2 Jul 2014

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The role of Oxalobacter formigenes colonization in calcium oxalate stone disease.
 

Author(s): Roswitha Siener, Ursula Bangen, Harmeet Sidhu, Ruth Hönow, Gerd von Unruh, Albrecht Hesse

Journal: Kidney Int.. 2013 Jun;83(6):1144-9.

 

About 75% of urinary stones contain oxalate. As Oxalobacter formigenes is a Gram-negative anaerobic bacterium that degrades oxalate in the intestinal tract, we assessed the role of O. formigenes in oxalate metabolism by evaluating its intestinal absorption, plasma concentration, and ...

Last Updated: 3 Jun 2013

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Renal histopathology and crystal deposits in patients with small bowel resection and calcium oxalate stone disease.
 

Author(s): Andrew P Evan, James E Lingeman, Elaine M Worcester, Sharon B Bledsoe, Andre J Sommer, James C Williams, Amy E Krambeck, Carrie L Philips, Fredric L Coe

Journal: Kidney Int.. 2010 Aug;78(3):310-7.

 

We present here the anatomy and histopathology of kidneys from 11 patients with renal stones following small bowel resection, including 10 with Crohn's disease and 1 resection in infancy for unknown cause. They presented predominantly with calcium oxalate stones. Risks of formation ...

Last Updated: 15 Jul 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oxalate Stone Disease" returned 3 free, full-text review articles on human participants. First 3 results:

Lowering urinary oxalate excretion to decrease calcium oxalate stone disease.
 

Author(s): Ross P Holmes, John Knight, Dean G Assimos

Journal: Urolithiasis. 2016 Feb;44(1):27-32.

 

Dietary modifications should be considered as a first line approach in the treatment of idiopathic calcium oxalate nephrolithiasis. The amounts of oxalate and calcium consumed in the diet are significant factors in the development of the disease due to their impact on urinary oxalate ...

Last Updated: 25 Jan 2016

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The genetic composition of Oxalobacter formigenes and its relationship to colonization and calcium oxalate stone disease.
 

Author(s): John Knight, Rajendar Deora, Dean G Assimos, Ross P Holmes

Journal: Urolithiasis. 2013 Jun;41(3):187-96.

 

Oxalobacter formigenes is a unique intestinal organism that relies on oxalate degradation to meet most of its energy and carbon needs. A lack of colonization is a risk factor for calcium oxalate stone disease. Protection against calcium oxalate stone disease appears to be due to the ...

Last Updated: 16 May 2013

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A critical analysis of the role of gut Oxalobacter formigenes in oxalate stone disease.
 

Author(s): Siddharth Siva, Evelyn R Barrack, G Prem Veer Reddy, Vijayalakshmi Thamilselvan, Sivagnanam Thamilselvan, Mani Menon, Mahendra Bhandari

Journal: BJU Int.. 2009 Jan;103(1):18-21.

 

Hyperoxaluria is a major risk factor for the formation of calcium oxalate stones, but dietary restriction of oxalate intake might not be a reliable approach to prevent recurrence of stones. Hence, other approaches to reduce urinary oxalate to manage stone disease have been explored. ...

Last Updated: 16 Dec 2008

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Rare Kidney Stone Consortium Patient Registry
 

Status: Recruiting

Condition Summary: Primary Hyperoxaluria; Dent Disease; Cystinuria; APRT Deficiency

 

Last Updated: 3 Aug 2017

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