Oxalate Stone Disease

Common Name(s)

Oxalate Stone Disease

Description for this condition is not yet available.
 

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Condition Specific Organizations

Following organizations serve the condition "Oxalate Stone Disease" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oxalate Stone Disease" returned 7 free, full-text research articles on human participants. First 3 results:

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease.
 

Author(s): Abhishek Albert, Vidhi Tiwari, Eldho Paul, Divya Ganesan, Mahesh Ayyavu, Ritu Kujur, Sasikumar Ponnusamy, Kathiresan Shanmugam, Luciano Saso, Selvam Govindan Sadasivam

Journal: J Enzyme Inhib Med Chem. 2017 Dec;32(1):426-433.

 

Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO. The present work is aimed to clone the oxdC gene in a ...

Last Updated: 31 Dec 1969

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Analysis of altered microRNA expression profiles in proximal renal tubular cells in response to calcium oxalate monohydrate crystal adhesion: implications for kidney stone disease.
 

Author(s): Bohan Wang, Bolin Wu, Jun Liu, Weimin Yao, Ding Xia, Lu Li, Zhiqiang Chen, Zhangqun Ye, Xiao Yu

Journal:

 

Calcium oxalate monohydrate (COM) is the major crystalline component in kidney stones and its adhesion to renal tubular cells leads to tubular injury. However, COM-induced toxic effects in renal tubular cells remain ambiguous. MicroRNAs (miRNAs) play an important role in gene regulation ...

Last Updated: 31 Dec 1969

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The role of Oxalobacter formigenes colonization in calcium oxalate stone disease.
 

Author(s): Roswitha Siener, Ursula Bangen, Harmeet Sidhu, Ruth Hönow, Gerd von Unruh, Albrecht Hesse

Journal: Kidney Int.. 2013 Jun;83(6):1144-9.

 

About 75% of urinary stones contain oxalate. As Oxalobacter formigenes is a Gram-negative anaerobic bacterium that degrades oxalate in the intestinal tract, we assessed the role of O. formigenes in oxalate metabolism by evaluating its intestinal absorption, plasma concentration, and ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oxalate Stone Disease" returned 4 free, full-text review articles on human participants. First 3 results:

Pathogenesis of calcium oxalate urinary stone disease: species comparison of humans, dogs, and cats.
 

Author(s): Allison L O'Kell, David C Grant, Saeed R Khan

Journal: Urolithiasis. 2017 Aug;45(4):329-336.

 

Idiopathic calcium oxalate nephrolithiasis is a highly recurrent disease that is increasing in prevalence. Decades of research have not identified effective methods to consistently prevent the formation of nephroliths or induce medical dissolution. Idiopathic calcium oxalate nephroliths ...

Last Updated: 31 Dec 1969

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Lowering urinary oxalate excretion to decrease calcium oxalate stone disease.
 

Author(s): Ross P Holmes, John Knight, Dean G Assimos

Journal: Urolithiasis. 2016 Feb;44(1):27-32.

 

Dietary modifications should be considered as a first line approach in the treatment of idiopathic calcium oxalate nephrolithiasis. The amounts of oxalate and calcium consumed in the diet are significant factors in the development of the disease due to their impact on urinary oxalate ...

Last Updated: 31 Dec 1969

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The genetic composition of Oxalobacter formigenes and its relationship to colonization and calcium oxalate stone disease.
 

Author(s): John Knight, Rajendar Deora, Dean G Assimos, Ross P Holmes

Journal: Urolithiasis. 2013 Jun;41(3):187-96.

 

Oxalobacter formigenes is a unique intestinal organism that relies on oxalate degradation to meet most of its energy and carbon needs. A lack of colonization is a risk factor for calcium oxalate stone disease. Protection against calcium oxalate stone disease appears to be due to the ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Rare Kidney Stone Consortium Patient Registry
 

Status: Recruiting

Condition Summary: Primary Hyperoxaluria; Dent Disease; Cystinuria; APRT Deficiency

 

Last Updated: 3 Aug 2017

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