Peeling skin syndrome

Common Name(s)

Peeling skin syndrome

Peeling skin syndrome is a genetic disorder characterized by continual peeling of the skin. Affected individuals may also experience itching and reddening of the skin. The signs and symptoms of peeling skin syndrome usually appear soon after birth, but they may also develop later in life. There are two main subtypes of this condition, called noninflammatory type A and inflammatory type B. In some families, an acral form of peeling skin syndrome has been reported, in which skin peeling is strictly limited to the hands and feet. Peeling skin syndrome has an autosomal recessive pattern of inheritance. Mutations in the TGM5 gene have been identified in several patients with the acral form of peeling skin syndrome.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Peeling skin syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Peeling skin syndrome" returned 16 free, full-text research articles on human participants. First 3 results:

Enhanced Proteolytic Activities in Acral Peeling Skin Syndrome: A Role of Transglutaminase 5 in Epidermal Homeostasis.
 

Author(s): Georgios Pampalakis, Dimitra Kiritsi, Eleni Zingkou, Claus-Werner Franzke, Manthoula Valari, Georgia Sotiropoulou

Journal: J. Invest. Dermatol.. 2017 08;137(8):1808-1811.

 

Last Updated: 31 Dec 1969

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The glycan-specific sulfotransferase (R77W)GalNAc-4-ST1 putatively responsible for peeling skin syndrome has normal properties consistent with a simple sequence polymorphisim.
 

Author(s): Dorothy Fiete, Yiling Mi, Mary Beranek, Nancy L Baenziger, Jacques U Baenziger

Journal: Glycobiology. 2017 05;27(5):450-456.

 

Expanded access to DNA sequencing now fosters ready detection of site-specific human genome alterations whose actual significance requires in-depth functional study to rule in or out disease-causing mutations. This is a particular concern for genomic sequence differences in glycosyltransferases, ...

Last Updated: 31 Dec 1969

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Peeling skin syndrome.
 

Author(s): Manish Bansal, Soniya Mahajan, Saumya Sankhwar, Alka Bansal

Journal:

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Peeling skin syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 13 Aug 2018

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Monitoring of the IOP After SLT Using iCare Home
 

Status: Recruiting

Condition Summary: Glaucoma Open-Angle Primary; Pseudo Exfoliation Syndrome

 

Last Updated: 10 Oct 2017

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IOP Monitoring After Trabeculectomy Using iCare Home
 

Status: Recruiting

Condition Summary: Glaucoma, Open-Angle; Pseudo Exfoliation Syndrome

 

Last Updated: 2 Oct 2018

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