Pericardial effusion

Common Name(s)

Pericardial effusion

Pericardial effusion occurs when too much fluid builds up between the heart and the pericardium, which is the thin sac that covers the heart. Most pericardial effusions are not harmful, but large pericardial effusions can restrict heart function. Most pericardial effusions are caused by pericarditis, which is the inflammation of the pericardium and caused most commonly by infection. Pericardial effusions may also be caused by certain cancers, kidney failure, and tuberculosis. Pericardial effusion symptoms include shortness of breath, discomfort in breathing, chest pain, cough, low-grade fever and rapid heart rate. Imaging tests, like x-rays, can be used to diagnose pericardial effusion. Pericardiocentesis is a procedure that can be used to diagnose the cause of a pericardial effusion as well as to treat the condition. This is a procedure that uses a needle to remove pericardial fluid from around the heart, which can then be examined. Treating the underlying cause of pericardial effusion will correct the problem in most cases though. Anti-inflammatory medications can help control pericarditis contributing to a pericardial effusion. Otherwise, more invasive procedures may be necessary to drain or prevent fluids from accumulating.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pericardial effusion" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pericardial effusion" returned 383 free, full-text research articles on human participants. First 3 results:

Hemorrhagic pericardial effusion as the debut of acquired hemophilia in a chronic lymphocytic leukemia patient: A case report, and a review of acquired hemophilia A-related hematological malignancies.
 

Author(s): José María Bastida, María Teresa Cano-Mozo, Felix Lopez-Cadenas, Victor Eduardo Vallejo, Soraya Merchán, Cecilia Santos-Montón, David González-Calle, Javier Carrillo, Ana Africa Martín, Jose Angel Torres-Hernández, Marcos González, Francisco Martín-Herrero, Pedro Pabón, Jose Ramon González-Porras

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8669.

 

Acquired hemophilia A (AHA) is a rare bleeding disease caused by autoantibodies against factor VIII. Spontaneous bleeding symptoms usually affect the skin and muscle, while pericardial effusion is an extremely rare manifestation. In the elderly, anticoagulant treatment is frequent ...

Last Updated: 31 Dec 1969

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Acute rhabdomyolysis and delayed pericardial effusion in an Italian patient with Ebola virus disease: a case report.
 

Author(s): Emanuele Nicastri, Antonio Brucato, Nicola Petrosillo, Gianluigi Biava, Timothy M Uyeki, Giuseppe Ippolito,

Journal:

 

During the 2013-2016 West Africa Ebola virus disease (EVD) epidemic, some EVD patients, mostly health care workers, were evacuated to Europe and the USA.

Last Updated: 31 Dec 1969

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Cytokine Profiles in Pericardial Effusion in a Down Syndrome Infant with Transient Abnormal Myelopoiesis.
 

Author(s): Yoshihiko Shitara, Naoto Takahashi, Yoshinori Aoki, Motohiro Kato, Riki Nishimura, Shinya Tsuchida, Akira Oka

Journal: Tohoku J. Exp. Med.. 2017 02;241(2):149-153.

 

Infants with Down Syndrome (DS) are at risk of developing a transient abnormal myelopoiesis (TAM). TAM is characterised by increased circulating blast cells but usually self-limiting. DS patients with TAM sometimes show fetal hydrops and effusion in body cavities, but the mechanism ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pericardial effusion" returned 18 free, full-text review articles on human participants. First 3 results:

The efficacy and safety of complete pericardial drainage by means of intrapericardial fibrinolysis for the prevention of complications of pericardial effusion: a systematic review protocol.
 

Author(s): Aloysious Kakia, Charles S Wiysonge, Eleanor A Ochodo, Abolade A Awotedu, Arsen D Ristic, Bongani M Mayosi

Journal:

 

Intrapericardial fibrinolysis has been proposed as a means of preventing complications of pericardial effusion such as cardiac tamponade, persistent and recurrent pericardial effusion, and pericardial constriction. There is a need to understand the efficacy and safety of this procedure ...

Last Updated: 31 Dec 1969

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[Pleuro-pericardial effusion revealing a lymphoblastic lymphoma].
 

Author(s): Yves N'da Kouakou N'goran, Kossa Esaïe Soya, Sylvanus Koui Beossin, Ines Angoran, Fatou Traore, Micesse Tano, Yaovi Afassinou, Arnaud Ekou, Florent Koffi, Hermann Yao, Euloge Kouadio Kramoh, Maurice Guikahue Kakou

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Last Updated: 31 Dec 1969

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Massive purulent pericardial effusion presenting as atrial fibrillation with rapid rate: case report and review of the literature.
 

Author(s): Amit Kathrotia, Mohan R Hindupur

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Although pericardial effusion with afib is not rare, the combination of purulent pericardial effusion presenting as afib is not a common occurrence particularly in the developing world.The more common symptoms associated with purulent pericardial effusion are fever, dyspenia, and ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion
 

Status: Recruiting

Condition Summary: Pericardial Effusion

 

Last Updated: 1 Feb 2016

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Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
 

Status: Recruiting

Condition Summary: Pericardial Effusion

 

Last Updated: 24 Apr 2017

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The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation
 

Status: Recruiting

Condition Summary: Atrial Fibrillation; Pericardial Effusion; Pleural Effusion; Hemothorax; Cardiac Tamponade

 

Last Updated: 17 Jun 2016

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