Pericardial effusion

Common Name(s)

Pericardial effusion

Pericardial effusion occurs when too much fluid builds up between the heart and the pericardium, which is the thin sac that covers the heart. Most pericardial effusions are not harmful, but large pericardial effusions can restrict heart function. Most pericardial effusions are caused by pericarditis, which is the inflammation of the pericardium and caused most commonly by infection. Pericardial effusions may also be caused by certain cancers, kidney failure, and tuberculosis. Pericardial effusion symptoms include shortness of breath, discomfort in breathing, chest pain, cough, low-grade fever and rapid heart rate. Imaging tests, like x-rays, can be used to diagnose pericardial effusion. Pericardiocentesis is a procedure that can be used to diagnose the cause of a pericardial effusion as well as to treat the condition. This is a procedure that uses a needle to remove pericardial fluid from around the heart, which can then be examined. Treating the underlying cause of pericardial effusion will correct the problem in most cases though. Anti-inflammatory medications can help control pericarditis contributing to a pericardial effusion. Otherwise, more invasive procedures may be necessary to drain or prevent fluids from accumulating.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pericardial effusion" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pericardial effusion" returned 374 free, full-text research articles on human participants. First 3 results:

Treatable massive pericardial effusion and hypertrophic cardiomyopathy in an infant with a novel homozygous ACADVL mutation: A case report.
 

Author(s): Yoo-Mi Kim, Geena Kim, Hoon Ko, Han-Wook Yoo, Hyoung Doo Lee

Journal: Medicine (Baltimore). 2018 May;97(20):e10813.

 

Infantile-onset hypertrophic cardiomyopathy (HCMP) should be considered a largely genetic condition, although its onset is most often triggered by infection. Very long chain acyl-CoA dehydrogenase (VLCAD) deficiency is a rare autosomal recessive inborn error of mitochondrial fatty ...

Last Updated: 31 Dec 1969

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Case report of refractory pericardial effusion associated with lymphatic fistula due to surgical injury during sternotomy.
 

Author(s): Lijun Jiang, Tingting Tao, Junnan Zheng, Zhen Jia, Hongfei Xu, Yiming Ni

Journal: Medicine (Baltimore). 2018 Mar;97(9):e9892.

 

A 35-year old Chinese female was admitted to hospital with refractory pericardial effusions 10 days post mitral valve replacement via median sternotomy. We performed an exploratory resternotomy and found lymphatic leakage on the surface of the diaphragm which was continuously emitting ...

Last Updated: 31 Dec 1969

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Hemorrhagic pericardial effusion as the debut of acquired hemophilia in a chronic lymphocytic leukemia patient: A case report, and a review of acquired hemophilia A-related hematological malignancies.
 

Author(s): José María Bastida, María Teresa Cano-Mozo, Felix Lopez-Cadenas, Victor Eduardo Vallejo, Soraya Merchán, Cecilia Santos-Montón, David González-Calle, Javier Carrillo, Ana Africa Martín, Jose Angel Torres-Hernández, Marcos González, Francisco Martín-Herrero, Pedro Pabón, Jose Ramon González-Porras

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8669.

 

Acquired hemophilia A (AHA) is a rare bleeding disease caused by autoantibodies against factor VIII. Spontaneous bleeding symptoms usually affect the skin and muscle, while pericardial effusion is an extremely rare manifestation. In the elderly, anticoagulant treatment is frequent ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pericardial effusion" returned 19 free, full-text review articles on human participants. First 3 results:

A systematic review of the efficacy and safety of intrapericardial fibrinolysis in patients with pericardial effusion.
 

Author(s): Alison B Wiyeh, Eleanor A Ochodo, Charles S Wiysonge, Aloysious Kakia, Abolade A Awotedu, Arsen Ristic, Bongani M Mayosi

Journal: Int. J. Cardiol.. 2018 Jan;250():223-228.

 

Pericardial effusion is the abnormal accumulation of fluid in the pericardial space. The complications of pericardial effusion can either be acute (e.g., cardiac tamponade) or chronic (e.g., constrictive pericarditis). We have conducted a systematic review of the scientific literature ...

Last Updated: 31 Dec 1969

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Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology.
 

Author(s): Karim Abdur Rehman, Jorge Betancor, Bo Xu, Arnav Kumar, Carlos Godoy Rivas, Kimi Sato, Leslie P Wong, Craig R Asher, Allan L Klein

Journal: Clin Cardiol. 2017 Oct;40(10):839-846.

 

A rising prevalence of end-stage renal disease (ESRD) has led to a rise in ESRD-related pericardial syndromes, calling for a better understanding of its pathophysiology, diagnoses, and management. Uremic pericarditis, the most common manifestation of uremic pericardial disease, is ...

Last Updated: 31 Dec 1969

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The efficacy and safety of complete pericardial drainage by means of intrapericardial fibrinolysis for the prevention of complications of pericardial effusion: a systematic review protocol.
 

Author(s): Aloysious Kakia, Charles S Wiysonge, Eleanor A Ochodo, Abolade A Awotedu, Arsen D Ristic, Bongani M Mayosi

Journal:

 

Intrapericardial fibrinolysis has been proposed as a means of preventing complications of pericardial effusion such as cardiac tamponade, persistent and recurrent pericardial effusion, and pericardial constriction. There is a need to understand the efficacy and safety of this procedure ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion
 

Status: Recruiting

Condition Summary: Pericardial Effusion

 

Last Updated: 30 Apr 2018

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Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
 

Status: Recruiting

Condition Summary: Pericardial Effusion

 

Last Updated: 3 Jun 2018

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Point-of-care Ultrasound in Finland
 

Status: Recruiting

Condition Summary: Deep Vein Thrombosis; Abdominal Aortic Aneurism; Pneumothorax; Gallbladder Diseases; Hydronephrosis; Pregnancy, Ectopic; Ascites; Pleural Effusion; Pericardial Effusion

 

Last Updated: 3 May 2018

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