Periodic Limb Movement Disorder

Common Name(s)

Periodic Limb Movement Disorder

Period limb movement disorder (PLMD) is characterized by rhythmic limb movement that occurs while you are asleep. Movements vary in severity, and typically affect the legs but can affect the arms as well. They can last from a few minutes to several hours. Many people with PLMD experience no symptoms, but some experience restless leg syndrome, or an uncomfortable sensation in the limbs. This condition can also contribute to insomnia or fatigue. The cause of PLMD is unknown, but it may be caused by abnormalities in the nervous system, certain diseases including Parkinson’s disease or narcolepsy, or some medications including antidepressants. PLMD is most often diagnosed by friends or family as they usually notice the disorder before you do, but can also be diagnosed with a sleep test. The is no known cure for PLMD, but it can be treated with drugs including Parkinson’s disease drugs, anticonvulsants, narcotics, and benzodiazepines. Antidepressants, caffeine, and low iron levels can worsen PLMD.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Periodic Limb Movement Disorder" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Periodic Limb Movement Disorder" returned 8 free, full-text research articles on human participants. First 3 results:

Bilateral globus pallidus internus deep brain stimulation in Parkinson's disease with periodic limb movement disorder.
 

Author(s): Bryan T Klassen, Mark K Lyons, Virgilio Gerald H Evidente

Journal: Turk Neurosurg. 2013 ;23(1):104-6.

 

Deep brain stimulation for Parkinson's disease is a well-established therapeutic intervention for refractory disease. The main nuclear targets are the subthalamic nucleus and the globus pallidus internus. Periodic limb movements are often an associated condition in patients with Parkinson's ...

Last Updated: 31 Dec 1969

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Update to the AASM Clinical Practice Guideline: "The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses".
 

Author(s): R Nisha Aurora, David A Kristo, Sabin R Bista, James A Rowley, Rochelle S Zak, Kenneth R Casey, Carin I Lamm, Sharon L Tracy, Richard S Rosenberg

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Last Updated: 31 Dec 1969

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Pediatric periodic limb movement disorder: sleep symptom and polysomnographic correlates compared to obstructive sleep apnea.
 

Author(s): Jeannine L Gingras, Jane F Gaultney, Daniel L Picchietti

Journal: J Clin Sleep Med. 2011 Dec;7(6):603-9A.

 

Although periodic limb movements in sleep (PLMS) have been described in multiple pediatric publications, periodic limb movement disorder (PLMD) has not. The aims of this study were to describe the prevalence, sleep-related correlates, and polysomnographic correlates of PLMD in a large ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Periodic Limb Movement Disorder" returned 1 free, full-text review articles on human participants. First 3 results:

The treatment of restless legs syndrome and periodic limb movement disorder in adults--an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline.
 

Author(s): R Nisha Aurora, David A Kristo, Sabin R Bista, James A Rowley, Rochelle S Zak, Kenneth R Casey, Carin I Lamm, Sharon L Tracy, Richard S Rosenberg,

Journal:

 

A systematic literature review and meta-analyses (where appropriate) were performed to update the previous AASM practice parameters on the treatments, both dopaminergic and other, of RLS and PLMD. A considerable amount of literature has been published since these previous reviews ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Link Between Clinical and Physiological Sleep Data and Health-related Outcomes
 

Status: Recruiting

Condition Summary: Sleep Apnea Syndromes; Cardiovascular Diseases; Sleep Initiation and Maintenance Disorders; Nocturnal Myoclonus Syndrome; Hospitalizations; Mortality; Cancer

 

Last Updated: 4 Jan 2018

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Infra-slow Oscillations During Sleep
 

Status: Recruiting

Condition Summary: Healthy Subjects; Restless Legs Syndrome; Periodic Limb Movements During Sleep

 

Last Updated: 12 Sep 2017

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