Peripheral artery disease

Common Name(s)

Peripheral artery disease

Peripheral artery disease (PAD) is a condition where the legs and/or arms do not receive enough blood. This condition develops most commonly in the legs and is usually caused by a buildup of fatty deposits in the arteries leading to the legs. Eventually, these deposits may result in narrowing of the arteries (atherosclerosis) putting the affected individual at risk for a heart attack or stroke. Other less common causes of PAD include inflammation (including swelling) of the arteries, certain leg injuries, certain problems with ligaments or muscles in the legs, and radiation exposure.

Individuals with PAD often feel pain while walking (intermittent claudication). Other symptoms include leg cramping, leg numbness or weakness, one leg feeling colder than the other, sores that don’t heal quickly, hair loss on legs, slow growing toenails, and skin that can be shiny or a different color.

The largest risk factor is smoking. Diabetes, obesity, high blood pressure, high cholesterol, aging, a family history, and high levels of a protein called homocysteine also increase your risk for developing PAD.

A diagnosis can be made in several ways. Your doctor may conduct a physical exam, perform an ultrasound, look at your blood vessels by injecting dye into them (angiography), or run blood tests. An ankle-brachial index (ABI) test may also be used to compare the blood pressure levels in your arms and legs. Some people with PAD can be treated with simple lifestyle changes, such as quitting smoking, exercising regularly, and eating healthy. In more severe cases, your doctor may prescribe certain medications or recommend surgery to stop the atherosclerosis from getting worse. Research is ongoing, so if you have been diagnosed with PAD, talk with your doctor and specialists about the most current treatment options. Support groups are good sources of information and can help connect you with others living with PAD.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Peripheral artery disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Peripheral artery disease" returned 457 free, full-text research articles on human participants. First 3 results:

Epidemiology of lower extremity peripheral artery disease in veterans.
 

Author(s): James Willey, Amgad Mentias, Mary Vaughan-Sarrazin, Kimberly McCoy, Gary Rosenthal, Saket Girotra

Journal: J. Vasc. Surg.. 2018 08;68(2):527-535.e5.

 

The objective of this study was to describe the epidemiology, clinical features, outcomes, and predictors of mortality in veterans with peripheral artery disease (PAD).

Last Updated: 31 Dec 1969

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Comparison of the Revenue Situation in Interventional Radiology Based on the Example of Peripheral Artery Disease in the Case of a DRG Payment System and Various Internal Treatment Charges.
 

Author(s): Florian M Vogt, Peter Hunold, Julian Haegele, Erik Stahlberg, Jörg Barkhausen, Jan Peter Goltz

Journal: Rofo. 2018 Apr;190(4):348-358.

 

 Calculation of process-orientated costs for inpatient endovascular treatment of peripheral artery disease (PAD) from an interventional radiology (IR) perspective. Comparison of revenue situations in consideration of different ways to calculate internal treatment charges (ITCs) ...

Last Updated: 31 Dec 1969

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Gait pattern in patients with peripheral artery disease.
 

Author(s): Maria Szymczak, Paweł Krupa, Grzegorz Oszkinis, Marian Majchrzycki

Journal:

 

The aim of the present paper is to assess the gait pattern of patients with Peripheral Artery Disease (PAD). A more specific aim is to compare the gait pattern of PAD patients before and after the appearance of intermittent claudication symptoms.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Peripheral artery disease" returned 68 free, full-text review articles on human participants. First 3 results:

PCSK9 inhibition for LDL lowering and beyond - implications for patients with peripheral artery disease.
 

Author(s): Katrin Gebauer, Holger Reinecke

Journal: VASA. 2018 Apr;47(3):165-176.

 

Low-density lipoprotein cholesterol (LDL-C) has been proven to be a causal factor of atherosclerosis and, along with other triggers like inflammation, the most frequent reason for peripheral arterial disease. Moreover, a linear correlation between LDL-C concentration and cardiovascular ...

Last Updated: 31 Dec 1969

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Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies.
 

Author(s): Mislav Vrsalović, Ana Vrsalović Presečki

Journal: Clin Cardiol. 2017 Dec;40(12):1231-1235.

 

Atrial fibrillation (AF) is associated with adverse outcomes in terms of survival and morbidity. Peripheral artery disease (PAD) and AF share several common risk factors and often coexist. Whether AF has a prognostic role in patients with PAD has not been extensively studied.

Last Updated: 31 Dec 1969

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Transpedal Access for the Management of Complex Peripheral Artery Disease.
 

Author(s): Konstantinos Marmagkiolis, Partha Sardar, Jihad A Mustapha, Miguel Montero-Baker, Konstantinos Charitakis, Cezar Iliescu, Dmitriy N Feldman

Journal: J Invasive Cardiol. 2017 Dec;29(12):425-429.

 

To evaluate the safety and efficacy of transpedal access for the management of complex peripheral artery disease (PAD).

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

SHOWME-PAD (Peripheral Artery Disease)
 

Status: Not yet recruiting

Condition Summary: Peripheral Artery Disease

 

Last Updated: 14 Jun 2017

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Daily Step-based Exercise Using Fitness Monitors for Peripheral Artery Disease
 

Status: Recruiting

Condition Summary: Peripheral Artery Disease

 

Last Updated: 14 Nov 2017

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