Platelet Disorders

Common Name(s)

Platelet Disorders

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Platelet Disorders" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Platelet Disorders" returned 66 free, full-text research articles on human participants. First 3 results:

Association of Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorders with Mean Platelet Volume and Vitamin D.
 

Author(s): Mesut Garipardic, Murat Doğan, Keziban Asli Bala, Tuba Mutluer, Sultan Kaba, Oktay Aslan, Lokman Üstyol

Journal:

 

BACKGROUND The purpose of this study was to assess the values of the mean platelet volume (MPV) in children with attention deficit hyperactivity disorder (ADHD) and with autism spectrum disorders (ASDs) to determine the risk of cardiovascular disease in these 2 disorder groups. MATERIAL ...

Last Updated: 20 Mar 2017

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Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders.
 

Author(s): Veronique Latger-Cannard, Christophe Philippe, Alexandre Bouquet, Veronique Baccini, Marie-Christine Alessi, Annick Ankri, Anne Bauters, Sophie Bayart, Pascale Cornillet-Lefebvre, Sylvie Daliphard, Marie-Joelle Mozziconacci, Aline Renneville, Paola Ballerini, Guy Leverger, Hagay Sobol, Philippe Jonveaux, Claude Preudhomme, Paquita Nurden, Thomas Lecompte, Remi Favier

Journal:

 

Less than 50 patients with FPD/AML (OMIM 601309) have been reported as of today and there may an underestimation. The purpose of this study was to describe the natural history, the haematological features and the genotype-phenotype correlations of this entity in order to, first, screen ...

Last Updated: 26 Apr 2016

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A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.
 

Author(s): Ilenia Simeoni, Jonathan C Stephens, Fengyuan Hu, Sri V V Deevi, Karyn Megy, Tadbir K Bariana, Claire Lentaigne, Sol Schulman, Suthesh Sivapalaratnam, Minka J A Vries, Sarah K Westbury, Daniel Greene, Sofia Papadia, Marie-Christine Alessi, Antony P Attwood, Matthias Ballmaier, Gareth Baynam, Emilse Bermejo, Marta Bertoli, Paul F Bray, Loredana Bury, Marco Cattaneo, Peter Collins, Louise C Daugherty, Rémi Favier, Deborah L French, Bruce Furie, Michael Gattens, Manuela Germeshausen, Cedric Ghevaert, Anne C Goodeve, Jose A Guerrero, Daniel J Hampshire, Daniel P Hart, Johan W M Heemskerk, Yvonne M C Henskens, Marian Hill, Nancy Hogg, Jennifer D Jolley, Walter H Kahr, Anne M Kelly, Ron Kerr, Myrto Kostadima, Shinji Kunishima, Michele P Lambert, Ri Liesner, José A López, Rutendo P Mapeta, Mary Mathias, Carolyn M Millar, Amit Nathwani, Marguerite Neerman-Arbez, Alan T Nurden, Paquita Nurden, Maha Othman, Kathelijne Peerlinck, David J Perry, Pawan Poudel, Pieter Reitsma, Matthew T Rondina, Peter A Smethurst, William Stevenson, Artur Szkotak, Salih Tuna, Christel van Geet, Deborah Whitehorn, David A Wilcox, Bin Zhang, Shoshana Revel-Vilk, Paolo Gresele, Daniel B Bellissimo, Christopher J Penkett, Michael A Laffan, Andrew D Mumford, Augusto Rendon, Keith Gomez, Kathleen Freson, Willem H Ouwehand, Ernest Turro

Journal: Blood. 2016 Jun;127(23):2791-803.

 

Inherited bleeding, thrombotic, and platelet disorders (BPDs) are diseases that affect ∼300 individuals per million births. With the exception of hemophilia and von Willebrand disease patients, a molecular analysis for patients with a BPD is often unavailable. Many specialized tests ...

Last Updated: 10 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Platelet Disorders" returned 30 free, full-text review articles on human participants. First 3 results:

Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders.
 

Author(s): Anna Lecchi, Eti A Femia, Silvia Paoletta, Arnaud Dupuis, Philippe Ohlmann, Christian Gachet, Kenneth A Jacobson, Katharina Machura, Gian M Podda, Barbara Zieger, Marco Cattaneo

Journal: Hamostaseologie. 2016 Nov;36(4):279-283.

 

The platelet adenosine 5'-diphosphate (ADP) receptor P2Y12 (P2Y12R) plays a critical role in platelet aggregation. The present report illustrates an update of dysfunctional platelet P2Y12R mutations diagnosed with congenital lifelong bleeding problems. Described patients with heterozygous ...

Last Updated: 4 Aug 2016

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Inherited platelet disorders: Insight from platelet genomics using next-generation sequencing.
 

Author(s): Annabel Maclachlan, Steve P Watson, Neil V Morgan

Journal: Platelets. 2017 Jan;28(1):14-19.

 

Inherited platelet disorders (IPDs) are a heterogeneous group of disorders associated with normal or reduced platelet counts and bleeding diatheses of varying severities. The identification of the underlying cause of IPDs is clinically challenging due to the absence of a gold-standard ...

Last Updated: 27 Jun 2016

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Inherited platelet disorders: toward DNA-based diagnosis.
 

Author(s): Claire Lentaigne, Kathleen Freson, Michael A Laffan, Ernest Turro, Willem H Ouwehand,

Journal: Blood. 2016 Jun;127(23):2814-23.

 

Variations in platelet number, volume, and function are largely genetically controlled, and many loci associated with platelet traits have been identified by genome-wide association studies (GWASs).(1) The genome also contains a large number of rare variants, of which a tiny fraction ...

Last Updated: 10 Jun 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Thrombocytopathy in Gaucher Disease Patients
 

Status: Recruiting

Condition Summary: Gaucher Disease; Thrombocytopathy

 

Last Updated: 27 Oct 2016

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Use of Proteomics for the Diagnosis of a Platelet-related Bleeding Disorder
 

Status: Not yet recruiting

Condition Summary: Inherited Platelet Disorders

 

Last Updated: 23 Mar 2016

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Safety and Efficacy of Eltrombopag at Escalated Doses
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia; Platelet Disorder

 

Last Updated: 30 Jan 2017

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