Pleomorphic Undifferentiated Sarcoma

Common Name(s)

Pleomorphic Undifferentiated Sarcoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pleomorphic Undifferentiated Sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pleomorphic Undifferentiated Sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pleomorphic Undifferentiated Sarcoma" returned 30 free, full-text research articles on human participants. First 3 results:

Synovium as a widespread pathway to the adjacent joint in undifferentiated high-grade pleomorphic sarcoma of the tibia: A case report.
 

Author(s): Xiaona Li, Zekun Zhang, Mahrukh Latif, Wei Chen, Jianling Cui, Zhigang Peng

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9870.

 

Undifferentiated high-grade pleomorphic sarcoma (UPS), originated from bone, is a rare tumor, accounting for 2% to 5% of all primary maligment bone neoplasms. Skip lesion can be found in undifferentiated high-grade pleomorphic sarcoma of bone (UPS-B). However, the direct invasion ...

Last Updated: 31 Dec 1969

Go To URL
Primary Culture of Undifferentiated Pleomorphic Sarcoma: Molecular Characterization and Response to Anticancer Agents.
 

Author(s): Alessandro De Vita, Federica Recine, Laura Mercatali, Giacomo Miserocchi, Chiara Spadazzi, Chiara Liverani, Alberto Bongiovanni, Federica Pieri, Roberto Casadei, Nada Riva, Valentina Fausti, Dino Amadori, Toni Ibrahim

Journal:

 

Undifferentiated pleomorphic sarcoma (UPS) is an aggressive mesenchymal neoplasm with no specific line of differentiation. Eribulin, a novel synthetic microtubule inhibitor, has shown anticancer activity in several tumors, including soft tissue sarcomas (STS). We investigated the ...

Last Updated: 31 Dec 1969

Go To URL
Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma.
 

Author(s): Caitlin D May, Sharon M Landers, Svetlana Bolshakov, XiaoYan Ma, Davis R Ingram, Christine M Kivlin, Kelsey L Watson, Ghadah A Al Sannaa, Angela D Bhalla, Wei-Lien Wang, Alexander J Lazar, Keila E Torres

Journal: Cancer Biol. Ther.. 2017 Oct;18(10):816-826.

 

Undifferentiated pleomorphic sarcomas (UPSs) are aggressive mesenchymal malignancies with no definitive cell of origin or specific recurrent genetic hallmarks. These tumors are largely chemoresistant; thus, identification of potential therapeutic targets is necessary to improve patient ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pleomorphic Undifferentiated Sarcoma" returned 5 free, full-text review articles on human participants. First 3 results:

Primary undifferentiated pleomorphic sarcoma of the thyroid: A case report and review of the literature.
 

Author(s): Qiang Chen, Qing Huang, Jia-Xin Yan, Chao Li, Jin-Yi Lang

Journal: Medicine (Baltimore). 2018 Feb;97(7):e9927.

 

Primary undifferentiated pleomorphic sarcoma is extremely rare in the thyroid, and can be easily misdiagnosed as anaplastic thyroid cancer.

Last Updated: 31 Dec 1969

Go To URL
Undifferentiated high-grade pleomorphic sarcoma of ethmoid sinus: a case report and literature review.
 

Author(s): Yupeng Zhu, Dapeng Hao, Xiaoyan Tang, Lei Sun

Journal: Braz J Otorhinolaryngol. ;84(3):389-392.

 

Last Updated: 31 Dec 1969

Go To URL
Aggressively progressing primary undifferentiated pleomorphic sarcoma in the eyelid: A case report and review of the literature.
 

Author(s): Won Choi, Jae Ha Hwang, Ga Eon Kim, Kyung Chul Yoon

Journal: Medicine (Baltimore). 2017 May;96(18):e6616.

 

Undifferentiated pleomorphic sarcoma is extremely rare in the head and neck area, and the aggressive nature of this tumor has not been previously described.

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Dec 2017

Go to URL

Last Updated: 2 Jul 2018

Go to URL
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma
 

Status: Recruiting

Condition Summary: Undifferentiated Pleomorphic Sarcoma; Liposarcoma; Chondrosarcoma; Osteosarcoma; Ewing Sarcoma

 

Last Updated: 24 Aug 2017

Go to URL