Poliomyelitis

Common Name(s)

Poliomyelitis, Polio

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 973 free, full-text research articles on human participants. First 3 results:

Progress Toward Poliomyelitis Eradication - Afghanistan, January 2016-June 2017.
 

Author(s): Maureen Martinez, Hemant Shukla, Joanna Nikulin, Mufti Zubair Wadood, Stephen Hadler, Chukwuma Mbaeyi, Rudolph Tangermann, Jaume Jorba, Derek Ehrhardt

Journal:

 

Afghanistan, Pakistan, and Nigeria remain the only countries where the transmission of endemic wild poliovirus type 1 (WPV1) continues (1). This report describes polio eradication activities, progress, and challenges in Afghanistan during January 2016-June 2017 and updates previous ...

Last Updated: 17 Aug 2017

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Poliomyelitis eradication – the review of notifications from the years 2010-2016 sent to National IHR Focal Point
 

Author(s): Franciszek Radziszewski, Janusz Janiec, Łukasz Henszel, Radosław Izdebski, Piotr Polański

Journal: Przegl Epidemiol. ;71(1):25-32.

 

Polio eradication programme was launched after World Health Assembly in 1988. Despite considerable decrease in reported cases it still constitutes a significant public health threat. All WHO member state is bound to appoint National IHR Focal Point, which operates based on International ...

Last Updated: 27 Jun 2017

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Risk factors and short-term projections for serotype-1 poliomyelitis incidence in Pakistan: A spatiotemporal analysis.
 

Author(s): Natalie A Molodecky, Isobel M Blake, Kathleen M O'Reilly, Mufti Zubair Wadood, Rana M Safdar, Amy Wesolowski, Caroline O Buckee, Ananda S Bandyopadhyay, Hiromasa Okayasu, Nicholas C Grassly

Journal:

 

Pakistan currently provides a substantial challenge to global polio eradication, having contributed to 73% of reported poliomyelitis in 2015 and 54% in 2016. A better understanding of the risk factors and movement patterns that contribute to poliovirus transmission across Pakistan ...

Last Updated: 12 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 27 free, full-text review articles on human participants. First 3 results:

Poliomyelitis: residual hurdles to global eradication. Commentary.
 

Author(s): Paola Stefanelli, Gabriele Buttinelli, Giovanni Rezza

Journal: Ann. Ist. Super. Sanita. ;52(4):469-471.

 

The global eradication of polio is close to achieving success. However, transmission of wild poliovirus persists in countries where the disease is endemic, and outbreaks may also occur in previously polio-free countries where population immunity is not maintained. To achieve polio ...

Last Updated: 21 Dec 2016

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Eradication and Current Status of Poliomyelitis in Pakistan: Ground Realities.
 

Author(s): Shazia Ghafoor, Nadeem Sheikh

Journal: J Immunol Res. 2016 ;2016():6837824.

 

Pakistan is among the last three countries along with Afghanistan and Nigeria, where polio virus is still endemic. More or less, with some fluctuations, numbers of reported cases in the past few years have shown a rising trend. Year 2014 pushed the country into the deep sea of difficulties, ...

Last Updated: 12 Aug 2016

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Comparison and Contrast of the Elimination Campaigns for Poliomyelitis and Leprosy: Which is More Feasible?
 

Author(s): Luís Malheiro, Sofia Correia Pinto, Antonio Sarmento, Lurdes Santos

Journal: Acta Med Port. 2016 Apr;29(4):279-83.

 

As we approach the third decade since the WHO started addressing the eradication of poliomyelitis and leprosy, a reflection of the previous campaigns efficacy and an evaluation of further elimination feasibility is important to adapt and intensify the next steps. We performed a critical ...

Last Updated: 28 Jun 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Jul 2017

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Last Updated: 23 Oct 2017

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