Poliomyelitis

Common Name(s)

Poliomyelitis, Polio

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 953 free, full-text research articles on human participants. First 3 results:

Progress Toward Poliomyelitis Eradication - Afghanistan, January 2017-May 2018.
 

Author(s): Maureen Martinez, Hemant Shukla, Maiwand Ahmadzai, Joanna Nikulin, Mufti Zubair Wadood, Jamal Ahmed, Chukwuma Mbaeyi, Jaume Jorba, Derek Ehrhardt

Journal:

 

Afghanistan, Pakistan, and Nigeria remain the only countries where transmission of endemic wild poliovirus type 1 (WPV1) continues (1). This report describes polio eradication activities, progress, and challenges to eradication in Afghanistan during January 2017-May 2018 and updates ...

Last Updated: 31 Dec 1969

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Progress Toward Poliomyelitis Eradication - Nigeria, January-December 2017.
 

Author(s): Omotayo Bolu, Chimeremma Nnadi, Eunice Damisa, Fiona Braka, Anisur Siddique, W Roodly Archer, Philip Bammeke, Richard Banda, Jeffrey Higgins, Aboyowa Edukugo, Gatei Wa Nganda, Joseph C Forbi, Hongmei Liu, Saheed Gidado, Mohammed Soghaier, Richard Franka, Ndadilnasiya Waziri, Cara C Burns, John Vertefeuille, Eric Wiesen, Usman Adamu

Journal:

 

Nearly three decades after the World Health Assembly launched the Global Polio Eradication Initiative in 1988, four of the six World Health Organization (WHO) regions have been certified polio-free (1). Nigeria is one of three countries, including Pakistan and Afghanistan, where wild ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 28 free, full-text review articles on human participants. First 3 results:

A systematic review of the worldwide prevalence of survivors of poliomyelitis reported in 31 studies.
 

Author(s): Kelly M Jones, Shivanthi Balalla, Alice Theadom, Gordon Jackman, Valery L Feigin

Journal:

 

Accurate prevalence figures estimating the number of survivors of poliomyelitis (disease causing acute flaccid paralysis) following poliovirus infection are not available. We aim to undertake a systematic review of all literature concerning the prevalence of survivors of poliomyelitis.

Last Updated: 31 Dec 1969

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Poliomyelitis: residual hurdles to global eradication. Commentary.
 

Author(s): Paola Stefanelli, Gabriele Buttinelli, Giovanni Rezza

Journal: Ann. Ist. Super. Sanita. ;52(4):469-471.

 

The global eradication of polio is close to achieving success. However, transmission of wild poliovirus persists in countries where the disease is endemic, and outbreaks may also occur in previously polio-free countries where population immunity is not maintained. To achieve polio ...

Last Updated: 31 Dec 1969

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Eradication and Current Status of Poliomyelitis in Pakistan: Ground Realities.
 

Author(s): Shazia Ghafoor, Nadeem Sheikh

Journal: J Immunol Res. 2016 ;2016():6837824.

 

Pakistan is among the last three countries along with Afghanistan and Nigeria, where polio virus is still endemic. More or less, with some fluctuations, numbers of reported cases in the past few years have shown a rising trend. Year 2014 pushed the country into the deep sea of difficulties, ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Jul 2017

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A Study to Evaluate the Safety and Immunogenicity of Novel Oral Polio Vaccine
 

Status: Not yet recruiting

Condition Summary: Poliomyelitis

 

Last Updated: 12 Jun 2018

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Characterization of the Immunological Profile Patients With Post-polio Syndrome
 

Status: Recruiting

Condition Summary: Poliomyelitis Sequelae

 

Last Updated: 10 Jan 2018

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