Poliomyelitis

Common Name(s)

Poliomyelitis, Polio

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Poliomyelitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Poliomyelitis" returned 965 free, full-text research articles on human participants. First 3 results:

Introduction of Inactivated Poliovirus Vaccine and Impact on Vaccine-Associated Paralytic Poliomyelitis - Beijing, China, 2014-2016.
 

Author(s): Dan Zhao, Rui Ma, Tao Zhou, Fan Yang, Jin Wu, Hao Sun, Fang Liu, Li Lu, Xiaomei Li, Shuyan Zuo, Wei Yao, Jian Yin

Journal:

 

When included in a sequential polio vaccination schedule, inactivated polio vaccine (IPV) reduces the risk for vaccine-associated paralytic poliomyelitis (VAPP), a rare adverse event associated with receipt of oral poliovirus vaccine (OPV). During January 2014, the World Health Organization ...

Last Updated: 31 Dec 1969

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Progress Toward Poliomyelitis Eradication - Pakistan, January 2016-September 2017.
 

Author(s): Youness Elhamidi, Abdirahman Mahamud, Muhammad Safdar, Wasan Al Tamimi, Jaume Jorba, Chukwuma Mbaeyi, Christopher H Hsu, Zubair Wadood, Salmaan Sharif, Derek Ehrhardt

Journal:

 

In 1988, the World Health Assembly launched the Global Polio Eradication Initiative. Among the three wild poliovirus serotypes, only wild poliovirus (WPV) type 1 (WPV1) has been detected since 2012. Since 2014, Pakistan, Afghanistan, and Nigeria remain the only countries with continuing ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Poliomyelitis" returned 27 free, full-text review articles on human participants. First 3 results:

Poliomyelitis: residual hurdles to global eradication. Commentary.
 

Author(s): Paola Stefanelli, Gabriele Buttinelli, Giovanni Rezza

Journal: Ann. Ist. Super. Sanita. ;52(4):469-471.

 

The global eradication of polio is close to achieving success. However, transmission of wild poliovirus persists in countries where the disease is endemic, and outbreaks may also occur in previously polio-free countries where population immunity is not maintained. To achieve polio ...

Last Updated: 31 Dec 1969

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Eradication and Current Status of Poliomyelitis in Pakistan: Ground Realities.
 

Author(s): Shazia Ghafoor, Nadeem Sheikh

Journal: J Immunol Res. 2016 ;2016():6837824.

 

Pakistan is among the last three countries along with Afghanistan and Nigeria, where polio virus is still endemic. More or less, with some fluctuations, numbers of reported cases in the past few years have shown a rising trend. Year 2014 pushed the country into the deep sea of difficulties, ...

Last Updated: 31 Dec 1969

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Comparison and Contrast of the Elimination Campaigns for Poliomyelitis and Leprosy: Which is More Feasible?
 

Author(s): Luís Malheiro, Sofia Correia Pinto, Antonio Sarmento, Lurdes Santos

Journal: Acta Med Port. 2016 Apr;29(4):279-83.

 

As we approach the third decade since the WHO started addressing the eradication of poliomyelitis and leprosy, a reflection of the previous campaigns efficacy and an evaluation of further elimination feasibility is important to adapt and intensify the next steps. We performed a critical ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Jul 2017

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Characterization of the Immunological Profile Patients With Post-polio Syndrome
 

Status: Recruiting

Condition Summary: Poliomyelitis Sequelae

 

Last Updated: 10 Jan 2018

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Last Updated: 21 Nov 2017

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