Polycystic ovarian syndrome

Common Name(s)

Polycystic ovarian syndrome, Stein-Leventhal syndrome

Polycystic ovarian syndrome (PCOS) is a condition caused by the hormone levels in a woman being unbalanced. The ovaries of women with PCOS produce higher than normal levels of male hormones (androgens). Insulin levels (the hormone which helps our cells use sugar and starches for energy) are also higher and may be linked to PCOS. PCOS is the leading cause of infertility. Between 1 in 10 to 20 women of childbearing age are affected by PCOS. PCOS may develop in girls as young as 10 years old.

Symptoms of PCOS may include the growth of small ovarian cysts (fluid filled sacs), acne, excessive hair growth, weight gain and problems with ovulation. Other symptoms include infrequent or absent periods, infertility, male patterned baldness, pelvic pain, sleep apnea, anxiety or depression. Symptoms and severity vary. Having a female relative with diabetes or PCOS may increase your risk.

Diagnosis of PCOS is made through a medical history, physical exam, blood tests and a vaginal ultrasound. Ovarian cysts and enlarged ovaries may be seen in an ultrasound. The lining of the uterus (endometrium) may be thicker in women with PCOS.

The cause of PCOS is unknown. PCOS may lead to infertility and increased risk of miscarriage, premature labor, preeclampsia, and gestational diabetes. PCOS also increases a woman’s risk for uterine cancer and diabetes later in life. High blood pressure and cholesterol levels can also be a result of PCOS and may lead to heart problems. Treatment for PCOS may include dietary changes, birth control pills, diabetes medication, fertility medications, surgery and androgen-reducing medication. If you have been diagnosed with PCOS, talk to your obstetrician or midwife as well as endocrinologist (a doctor who specializes in treating hormonal conditions) about the most current treatment options. Support groups are a good source of information and can connect you with other women who are living with PCOS.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polycystic ovarian syndrome" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polycystic ovarian syndrome" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polycystic ovarian syndrome" returned 130 free, full-text research articles on human participants. First 3 results:

Clomiphene citrate is associated with favorable cycle characteristics but impaired outcomes of obese women with polycystic ovarian syndrome undergoing ovarian stimulation for in vitro fertilization.
 

Author(s): Shutian Jiang, Yanping Kuang

Journal: Medicine (Baltimore). 2017 Aug;96(32):e7540.

 

The aim of this study was to explore the effect of clomiphene citrate (CC) on the cycle characteristics and outcomes of obese women with polycystic ovarian syndrome (PCOS) undergoing ovarian stimulation for in vitro fertilization (IVF).This is a retrospective cohort study, and it ...

Last Updated: 10 Aug 2017

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Bisphenol A and Ovarian Reserve among Infertile Women with Polycystic Ovarian Syndrome.
 

Author(s): Wei Zhou, Fang Fang, Wenting Zhu, Zi-Jiang Chen, Yanzhi Du, Jun Zhang

Journal:

 

To better understand possible effects of bisphenol A (BPA) exposure on ovarian reserve in women with polycystic ovary syndrome (PCOS), we measured creatinine adjusted urinary BPA (BPA_Cre) concentrations and used regression models to evaluate the association between urinary BPA level ...

Last Updated: 30 Dec 2016

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Short and Long-Term Efficacy of Laparoscopic Ovarian Diathermy in Women with Polycystic Ovary Syndrome.
 

Author(s): Rita Luz, Joana Barros, Ana Aguiar, Cátia Rodrigues, Ana Paula Soares, Joaquim Nunes, Sandra Sousa, Carlos Calhaz-Jorge

Journal: Acta Med Port. 2016 Aug;29(7-8):441-448.

 

Polycystic ovary syndrome is the most frequent cause of anovulatory infertility and management involves a multistep approach. Laparoscopic ovarian diathermy is accepted as a second-line treatment of patients who failed to respond to clomiphene citrate. The aims of this study were ...

Last Updated: 3 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polycystic ovarian syndrome" returned 27 free, full-text review articles on human participants. First 3 results:

Acupuncture for polycystic ovarian syndrome: A systematic review and meta-analysis.
 

Author(s): Junyoung Jo, Yoon Jae Lee, Hyangsook Lee

Journal: Medicine (Baltimore). 2017 Jun;96(23):e7066.

 

This systematic review aimed at summarizing and evaluating the evidence from randomized controlled trials (RCTs) using acupuncture to treat polycystic ovarian syndrome (PCOS), specifically focusing on ovulation rate, menstrual rate, and related hormones.

Last Updated: 7 Jun 2017

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Animal models of hyperandrogenism and ovarian morphology changes as features of polycystic ovary syndrome: a systematic review.
 

Author(s): Larissa Paixão, Ramon B Ramos, Anita Lavarda, Debora M Morsh, Poli Mara Spritzer

Journal:

 

Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 9-18% of women in reproductive age that causes hyperandrogenism and infertility due to dysfunctional follicular maturation and anovulation. The etiology of PCOS is still poorly known, and information from experimental ...

Last Updated: 10 Feb 2017

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From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines.
 

Author(s): Chiara Sartori, Pietro Lazzeroni, Silvia Merli, Viviana Dora Patianna, Francesca Viaroli, Francesca Cirillo, Sergio Amarri, Maria Elisabeth Street

Journal: Mediators Inflamm.. 2016 ;2016():4981916.

 

Adipokines are cytokines produced mainly by adipose tissue, besides many other tissues such as placenta, ovaries, peripheral-blood mononuclear cells, liver, muscle, kidney, heart, and bone marrow. Adipokines play a significant role in the metabolic syndrome and in cardiovascular diseases, ...

Last Updated: 17 Oct 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Paleo Versus Healthy ADA Diets for Treatment of Polycystic Ovarian Syndrome (PCOS)
 

Status: Recruiting

Condition Summary: Polycystic Ovarian Syndrome

 

Last Updated: 24 Jul 2017

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Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome
 

Status: Recruiting

Condition Summary: Polycystic Ovarian Syndrome

 

Last Updated: 5 Oct 2017

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The Genetics of Polycystic Ovarian Syndrome
 

Status: Recruiting

Condition Summary: Polycystic Ovary Syndrome

 

Last Updated: 27 Mar 2017

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