Polymyositis

Common Name(s)

Polymyositis

Polymyositis is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness.  Polymyositis affects skeletal muscles (those involved with making movement) on both sides of the body.  It is rarely seen in persons under age 18; most cases are seen in adults between the ages of 31 and 60. The cause of polymyositis is not fully understood.  Although there's no cure for polymyositis, treatment can improve muscle strength and function.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Polymyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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General Resources

Polymyositis

Learn more about Polymyositis, rare, autoimmune muscle disease.

Updated 3 Mar 2018

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Polymyositis" returned 387 free, full-text research articles on human participants. First 3 results:

Hyaluronic acid in dermatomyositis and polymyositis: relationship with disease and cutaneous lesions.
 

Author(s): Marilda Guimarães Silva, Samuel Katsuyuki Shinjo

Journal: An Bras Dermatol. ;93(1):72-75.

 

There are scarce studies in the literature about hyaluronic acid in systemic autoimmune myopathies.

Last Updated: 31 Dec 1969

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Hospitalization mortality and associated risk factors in patients with polymyositis and dermatomyositis: A retrospective case-control study.
 

Author(s): Chanyuan Wu, Qian Wang, Linrong He, Enhao Yang, Xiaofeng Zeng

Journal:

 

Polymyositis and dermatomyositis (PM/DM) are systemic autoimmune diseases with multiple organ involvements that manifest as muscular and cutaneous disorders, interstitial lung disease (ILD) and malignancies. However, information concerning the outcomes and associated factors for PM/DM ...

Last Updated: 31 Dec 1969

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[A case of anti-PL-7 antibody positive polymyositis with thrombotic microangiopathy].
 

Author(s): Masao Tamura, Masayasu Kitano, Kouta Azuma, Kazuyuki Tsuboi, Takeo Abe, Chie Ogita, Yuichi Yokoyama, Tetsuya Furukawa, Takahiro Yoshikawa, Atsushi Saito, Aki Nishioka, Masahiro Sekiguchi, Naoto Azuma, Shinichiro Tsunoda, Yuji Hosono, Ran Nakashima, Koichiro Ohmura, Kiyoshi Matsui, Tsuneyo Mimori, Hajime Sano

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2017 ;40(6):450-455.

 

  A 65-year-old woman with a 17-year history of polymyositis and 8-year history of rheumatoid arthritis who was treated with a low dose of prednisolone and tacrolimus (Tac) was admitted to our hospital because of general malaise and hypertension. Blood tests showed thrombocytopenia, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Polymyositis" returned 44 free, full-text review articles on human participants. First 3 results:

Limb-girdle muscular dystrophy type 2B misdiagnosed as polymyositis at the early stage: Case report and literature review.
 

Author(s): Chuan Xu, Jiajun Chen, Yingyu Zhang, Jia Li

Journal: Medicine (Baltimore). 2018 May;97(21):e10539.

 

Dysferlin myopathy is an autosomal recessive hereditary muscular dystrophy due to deficiency of dysferlin caused by alteration of the DYSF gene; Limb-girdle muscular dystrophy type 2B (LGMD2B) is the most common in Its clinical phenotypes. However, LGMD2B is rarely seen in clinical ...

Last Updated: 31 Dec 1969

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Sarcoid Myopathy Mimicking Polymyositis: A Case Report and Pool Analysis of the Literature Reviews.
 

Author(s): Syahrul Sazliyana Shaharir, Adawiyah Jamil, Sumitro Kosasih, Low Soo Fin, Radhika Sridharan, Suria Hayati Md Pauzi

Journal: Acta Med Iran. 2017 Dec;55(12):800-806.

 

A 59-year-old man presented with proximal myopathy, myalgia, and weight loss, with the initial markedly elevated serum creatine kinase at 11,000 U/L. Due to his refusal for muscle biopsy, he was initially treated as inflammatory myositis and responded well with the corticosteroids. ...

Last Updated: 31 Dec 1969

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Polymyositis with elevated serum IgG4 levels and abundant IgG4+ plasma cell infiltration: A case report and literature review.
 

Author(s): Ryusuke Anan, Mitsuhiro Akiyama, Yuko Kaneko, Jun Kikuchi, Kazuko Suzuki, Shiro Matsubara, Tsutomu Takeuchi

Journal: Medicine (Baltimore). 2017 Dec;96(48):e8710.

 

Polymyositis (PM) is a type of autoimmune, inflammatory myopathy. IgG4-related disease (IgG4-RD) is a recently recognized disease entity characterized by elevated serum IgG4 levels and IgG4 plasma-cell infiltration of various organs. However, several reports have described cases of ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Polymyositis

 

Last Updated: 30 Oct 2017

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Effects of High-intensity Interval Training (HIIT) in Recent Onset Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Polymyositis; Dermatomyositis

 

Last Updated: 20 Apr 2018

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Lipid-lowering Agents in Patients With Dermatomyositis and Polymyositis
 

Status: Recruiting

Condition Summary: Treatment Side Effects

 

Last Updated: 9 May 2018

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